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Patrick E. MacDonald
Patrick E. MacDonald
Preverjeni e-poštni naslov na ualberta.ca - Domača stran
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Leto
A pancreatic islet-specific microRNA regulates insulin secretion
MN Poy, L Eliasson, J Krutzfeldt, S Kuwajima, X Ma, PE Macdonald, ...
Nature 432 (7014), 226-230, 2004
27512004
The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion
PE MacDonald, W El-Kholy, MJ Riedel, AMF Salapatek, PE Light, ...
Diabetes 51 (suppl_3), S434-S442, 2002
7562002
The cell biology of systemic insulin function
VL Tokarz, PE MacDonald, A Klip
Journal of Cell Biology 217 (7), 2273-2289, 2018
5962018
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas
JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ...
Nature metabolism 3 (2), 149-165, 2021
5392021
Glucose-sensing mechanisms in pancreatic β-cells
PE MacDonald, JW Joseph, P Rorsman
Philosophical Transactions of the Royal Society B: Biological Sciences 360 …, 2005
4712005
MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation
Z Pang, Y Lu, G Zhou, F Hui, L Xu, C Viau, AF Spigelman, PE MacDonald, ...
Nucleic acids research 52 (W1), W398-W406, 2024
3622024
Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.
CB Chan, PE MacDonald, MC Saleh, DC Johns, E Marban, MB Wheeler
Diabetes 48 (7), 1482-1486, 1999
3371999
Voltage-dependent K+ channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets
PE MacDonald, MB Wheeler
Diabetologia 46, 1046-1062, 2003
3212003
A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans
PE MacDonald, YZD Marinis, R Ramracheya, A Salehi, X Ma, ...
PLoS biology 5 (6), e143, 2007
3182007
Patch-seq links single-cell transcriptomes to human islet dysfunction in diabetes
J Camunas-Soler, XQ Dai, Y Hang, A Bautista, J Lyon, K Suzuki, SK Kim, ...
Cell metabolism 31 (5), 1017-1031. e4, 2020
2572020
Members of the Kv1 and Kv2 Voltage-Dependent K+ Channel Families Regulate Insulin Secretion
PE MacDonald, XF Ha, J Wang, SR Smukler, AM Sun, HY Gaisano, ...
Molecular endocrinology 15 (8), 1423-1435, 2001
2442001
β Cell tone is defined by proglucagon peptides through cAMP signaling
ME Capozzi, B Svendsen, SE Encisco, SL Lewandowski, MD Martin, ...
JCI insight 4 (5), e126742, 2019
2372019
Converting adult pancreatic islet α cells into β cells by targeting both Dnmt1 and Arx
H Chakravarthy, X Gu, M Enge, X Dai, Y Wang, N Damond, C Downie, ...
Cell metabolism 25 (3), 622-634, 2017
2262017
Inhibition of Kv2. 1 voltage-dependent K+ channels in pancreatic β-cells enhances glucose-dependent insulin secretion
PE MacDonald, S Sewing, J Wang, JW Joseph, SR Smukler, ...
Journal of Biological Chemistry 277 (47), 44938-44945, 2002
2192002
Transcript expression data from human islets links regulatory signals from genome-wide association studies for type 2 diabetes and glycemic traits to their downstream effectors
M van de Bunt, JE Manning Fox, X Dai, A Barrett, C Grey, L Li, AJ Bennett, ...
PLoS genetics 11 (12), e1005694, 2015
1972015
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells
M Ferdaoussi, X Dai, MV Jensen, R Wang, BS Peterson, C Huang, ...
The Journal of clinical investigation 125 (10), 3847-3860, 2015
1922015
SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β-and α-cells
B Kailey, M van de Bunt, S Cheley, PR Johnson, PE MacDonald, ...
American journal of physiology-endocrinology and metabolism 303 (9), E1107-E1116, 2012
1902012
Cystic fibrosis–related diabetes is caused by islet loss and inflammation
NJ Hart, R Aramandla, G Poffenberger, C Fayolle, AH Thames, A Bautista, ...
JCI insight 3 (8), e98240, 2018
1872018
G protein-coupled receptor (GPR) 40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1
M Ferdaoussi, V Bergeron, B Zarrouki, J Kolic, J Cantley, J Fielitz, ...
Diabetologia 55, 2682-2692, 2012
1862012
Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells
PE MacDonald, M Braun, J Galvanovskis, P Rorsman
Cell metabolism 4 (4), 283-290, 2006
1702006
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