A pancreatic islet-specific microRNA regulates insulin secretion MN Poy, L Eliasson, J Krutzfeldt, S Kuwajima, X Ma, PE Macdonald, ... Nature 432 (7014), 226-230, 2004 | 2751 | 2004 |
The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion PE MacDonald, W El-Kholy, MJ Riedel, AMF Salapatek, PE Light, ... Diabetes 51 (suppl_3), S434-S442, 2002 | 756 | 2002 |
The cell biology of systemic insulin function VL Tokarz, PE MacDonald, A Klip Journal of Cell Biology 217 (7), 2273-2289, 2018 | 596 | 2018 |
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ... Nature metabolism 3 (2), 149-165, 2021 | 539 | 2021 |
Glucose-sensing mechanisms in pancreatic β-cells PE MacDonald, JW Joseph, P Rorsman Philosophical Transactions of the Royal Society B: Biological Sciences 360 …, 2005 | 471 | 2005 |
MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation Z Pang, Y Lu, G Zhou, F Hui, L Xu, C Viau, AF Spigelman, PE MacDonald, ... Nucleic acids research 52 (W1), W398-W406, 2024 | 362 | 2024 |
Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets. CB Chan, PE MacDonald, MC Saleh, DC Johns, E Marban, MB Wheeler Diabetes 48 (7), 1482-1486, 1999 | 337 | 1999 |
Voltage-dependent K+ channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets PE MacDonald, MB Wheeler Diabetologia 46, 1046-1062, 2003 | 321 | 2003 |
A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans PE MacDonald, YZD Marinis, R Ramracheya, A Salehi, X Ma, ... PLoS biology 5 (6), e143, 2007 | 318 | 2007 |
Patch-seq links single-cell transcriptomes to human islet dysfunction in diabetes J Camunas-Soler, XQ Dai, Y Hang, A Bautista, J Lyon, K Suzuki, SK Kim, ... Cell metabolism 31 (5), 1017-1031. e4, 2020 | 257 | 2020 |
Members of the Kv1 and Kv2 Voltage-Dependent K+ Channel Families Regulate Insulin Secretion PE MacDonald, XF Ha, J Wang, SR Smukler, AM Sun, HY Gaisano, ... Molecular endocrinology 15 (8), 1423-1435, 2001 | 244 | 2001 |
β Cell tone is defined by proglucagon peptides through cAMP signaling ME Capozzi, B Svendsen, SE Encisco, SL Lewandowski, MD Martin, ... JCI insight 4 (5), e126742, 2019 | 237 | 2019 |
Converting adult pancreatic islet α cells into β cells by targeting both Dnmt1 and Arx H Chakravarthy, X Gu, M Enge, X Dai, Y Wang, N Damond, C Downie, ... Cell metabolism 25 (3), 622-634, 2017 | 226 | 2017 |
Inhibition of Kv2. 1 voltage-dependent K+ channels in pancreatic β-cells enhances glucose-dependent insulin secretion PE MacDonald, S Sewing, J Wang, JW Joseph, SR Smukler, ... Journal of Biological Chemistry 277 (47), 44938-44945, 2002 | 219 | 2002 |
Transcript expression data from human islets links regulatory signals from genome-wide association studies for type 2 diabetes and glycemic traits to their downstream effectors M van de Bunt, JE Manning Fox, X Dai, A Barrett, C Grey, L Li, AJ Bennett, ... PLoS genetics 11 (12), e1005694, 2015 | 197 | 2015 |
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells M Ferdaoussi, X Dai, MV Jensen, R Wang, BS Peterson, C Huang, ... The Journal of clinical investigation 125 (10), 3847-3860, 2015 | 192 | 2015 |
SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β-and α-cells B Kailey, M van de Bunt, S Cheley, PR Johnson, PE MacDonald, ... American journal of physiology-endocrinology and metabolism 303 (9), E1107-E1116, 2012 | 190 | 2012 |
Cystic fibrosis–related diabetes is caused by islet loss and inflammation NJ Hart, R Aramandla, G Poffenberger, C Fayolle, AH Thames, A Bautista, ... JCI insight 3 (8), e98240, 2018 | 187 | 2018 |
G protein-coupled receptor (GPR) 40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1 M Ferdaoussi, V Bergeron, B Zarrouki, J Kolic, J Cantley, J Fielitz, ... Diabetologia 55, 2682-2692, 2012 | 186 | 2012 |
Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells PE MacDonald, M Braun, J Galvanovskis, P Rorsman Cell metabolism 4 (4), 283-290, 2006 | 170 | 2006 |