| Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution AN Hosein, H Huang, Z Wang, K Parmar, W Du, J Huang, A Maitra, ... JCI insight 4 (16), e129212, 2019 | 277 | 2019 |
| Small-molecule inhibition of Axl targets tumor immune suppression and enhances chemotherapy in pancreatic cancer KF Ludwig, W Du, NB Sorrelle, K Wnuk-Lipinska, M Topalovski, ... Cancer research 78 (1), 246-255, 2018 | 150 | 2018 |
| Inhibition of discoidin domain receptor 1 reduces collagen-mediated tumorigenicity in pancreatic ductal adenocarcinoma KY Aguilera, H Huang, W Du, MM Hagopian, Z Wang, S Hinz, TH Hwang, ... Molecular cancer therapeutics 16 (11), 2473-2485, 2017 | 111 | 2017 |
| Sitravatinib potentiates immune checkpoint blockade in refractory cancer models W Du, H Huang, N Sorrelle, RA Brekken JCI insight 3 (21), e124184, 2018 | 108 | 2018 |
| Arginase 1 is a key driver of immune suppression in pancreatic cancer RE Menjivar, ZC Nwosu, W Du, KL Donahue, HS Hong, C Espinoza, ... Elife 12, e80721, 2023 | 78 | 2023 |
| Targeting TGF βR2‐mutant tumors exposes vulnerabilities to stromal TGF β blockade in pancreatic cancer H Huang, Y Zhang, V Gallegos, N Sorrelle, MM Zaid, J Toombs, W Du, ... EMBO molecular medicine 11 (11), e10515, 2019 | 78 | 2019 |
| Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming A Velez-Delgado, KL Donahue, KL Brown, W Du, V Irizarry-Negron, ... Cellular and molecular gastroenterology and hepatology 13 (6), 1673-1699, 2022 | 70 | 2022 |
| Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer X Li, X Wan, H Chen, S Yang, Y Liu, W Mo, D Meng, W Du, Y Huang, ... Clinical Cancer Research 20 (9), 2312-2325, 2014 | 67 | 2014 |
| Telomerase-mediated strategy for overcoming non–small cell lung cancer targeted therapy and chemotherapy resistance I Mender, R LaRanger, K Luitel, M Peyton, L Girard, TP Lai, K Batten, ... Neoplasia 20 (8), 826-837, 2018 | 66 | 2018 |
| Structure-based design of tetrahydroisoquinoline-7-carboxamides as selective discoidin domain receptor 1 (DDR1) inhibitors Z Wang, H Bian, SG Bartual, W Du, J Luo, H Zhao, S Zhang, C Mo, Y Zhou, ... Journal of medicinal chemistry 59 (12), 5911-5916, 2016 | 64 | 2016 |
| Analysis of donor pancreata defines the transcriptomic signature and microenvironment of early neoplastic lesions ES Carpenter, AM Elhossiny, P Kadiyala, J Li, J McGue, BD Griffith, ... Cancer discovery 13 (6), 1324-1345, 2023 | 62 | 2023 |
| Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer VH Cruz, EN Arner, W Du, AE Bremauntz, RA Brekken JCI insight 4 (9), e126117, 2019 | 47 | 2019 |
| WNT signaling in the tumor microenvironment promotes immunosuppression in murine pancreatic cancer W Du, RE Menjivar, KL Donahue, P Kadiyala, A Velez-Delgado, ... Journal of Experimental Medicine 220 (1), e20220503, 2022 | 42 | 2022 |
| Tetrahydroisoquinoline-7-carboxamide derivatives as new selective discoidin domain receptor 1 (DDR1) inhibitors Z Wang, Y Zhang, SG Bartual, J Luo, T Xu, W Du, Q Xun, Z Tu, ... ACS medicinal chemistry letters 8 (3), 327-332, 2017 | 42 | 2017 |
| Behind the wheel of epithelial plasticity in KRAS-driven cancers EN Arner, W Du, RA Brekken Frontiers in oncology 9, 1049, 2019 | 32 | 2019 |
| Extracellular matrix induction of intracellular reactive oxygen species H Huang, W Du, RA Brekken Antioxidants & Redox Signaling 27 (12), 774-784, 2017 | 30 | 2017 |
| AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer W Du, NZ Phinney, H Huang, Z Wang, J Westcott, JE Toombs, Y Zhang, ... Molecular Cancer Research 19 (8), 1412-1421, 2021 | 27 | 2021 |
| Does Axl have potential as a therapeutic target in pancreatic cancer? W Du, RA Brekken Expert opinion on therapeutic targets 22 (11), 955-966, 2018 | 27 | 2018 |
| Therapeutic potential of targeting stromal crosstalk-mediated immune suppression in pancreatic cancer W Du, M Pasca di Magliano, Y Zhang Frontiers in Oncology 11, 682217, 2021 | 18 | 2021 |
| Notch signaling regulates immunosuppressive tumor-associated macrophage function in pancreatic cancer W Yan, RE Menjivar, ME Bonilla, NG Steele, SB Kemp, W Du, ... Cancer immunology research 12 (1), 91-106, 2024 | 14 | 2024 |