| Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA AS Tan, JW Baty, LF Dong, A Bezawork-Geleta, B Endaya, J Goodwin, ... Cell metabolism 21 (1), 81-94, 2015 | 783 | 2015 |
| α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II LF Dong, P Low, JC Dyason, XF Wang, L Prochazka, PK Witting, ... Oncogene 27 (31), 4324-4335, 2008 | 342 | 2008 |
| Mitochondrial complex II: at the crossroads A Bezawork-Geleta, J Rohlena, L Dong, K Pacak, J Neuzil Trends in biochemical sciences 42 (4), 312-325, 2017 | 293 | 2017 |
| Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Bezawork-Geleta, D Svec, ... elife 6, e22187, 2017 | 288 | 2017 |
| Classification of mitocans, anti-cancer drugs acting on mitochondria J Neuzil, LF Dong, J Rohlena, J Truksa, SJ Ralph Mitochondrion 13 (3), 199-208, 2013 | 281 | 2013 |
| Tumour-initiating cells vs. cancer ‘stem’cells and CD133: what’s in the name? J Neuzil, M Stantic, R Zobalova, J Chladova, X Wang, L Prochazka, ... Biochemical and biophysical research communications 355 (4), 855-859, 2007 | 266 | 2007 |
| Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 254 | 2019 |
| Molecular mechanism of ‘mitocan’-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins J Neuzil, XF Wang, LF Dong, P Low, SJ Ralph FEBS letters 580 (22), 5125-5129, 2006 | 246 | 2006 |
| Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ... Journal of Biological Chemistry 286 (5), 3717-3728, 2011 | 244 | 2011 |
| Vitamin E analogs, a novel group of “mitocans,” as anticancer agents: the importance of being redox-silent J Neuzil, M Tomasetti, Y Zhao, LF Dong, M Birringer, XF Wang, P Low, ... Molecular pharmacology 71 (5), 1185-1199, 2007 | 178 | 2007 |
| Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II J Neuzil, JC Dyason, R Freeman, LF Dong, L Prochazka, XF Wang, ... Journal of bioenergetics and biomembranes 39, 65-72, 2007 | 158 | 2007 |
| Mitochondrially targeted anti-cancer agents L Biasutto, LF Dong, M Zoratti, J Neuzil Mitochondrion 10 (6), 670-681, 2010 | 156 | 2010 |
| Suppression of tumor growth in vivo by the mitocan α-tocopheryl succinate requires respiratory complex II LF Dong, R Freeman, J Liu, R Zobalova, A Marin-Hernandez, M Stantic, ... Clinical Cancer Research 15 (5), 1593-1600, 2009 | 149 | 2009 |
| Mitochondrial complex II, a novel target for anti-cancer agents K Kluckova, A Bezawork-Geleta, J Rohlena, L Dong, J Neuzil Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 552-564, 2013 | 143 | 2013 |
| Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria J Neuzil, LF Dong, L Ramanathapuram, T Hahn, M Chladova, XF Wang, ... Molecular aspects of medicine 28 (5-6), 607-645, 2007 | 135 | 2007 |
| Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer K Rohlenova, K Sachaphibulkij, J Stursa, A Bezawork-Geleta, J Blecha, ... Antioxidants & redox signaling 26 (2), 84-103, 2017 | 134 | 2017 |
| A peptide conjugate of vitamin E succinate targets breast cancer cells with high ErbB2 expression XF Wang, M Birringer, LF Dong, P Veprek, P Low, E Swettenham, ... Cancer Research 67 (7), 3337-3344, 2007 | 134 | 2007 |
| Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy LF Dong, VJA Jameson, D Tilly, L Prochazka, J Rohlena, K Valis, J Truksa, ... Free Radical Biology and Medicine 50 (11), 1546-1555, 2011 | 129 | 2011 |
| Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress LF Dong, E Swettenham, J Eliasson, XF Wang, M Gold, Y Medunic, ... Cancer research 67 (24), 11906-11913, 2007 | 126 | 2007 |
| Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress K Ito, SA Scott, S Cutler, LF Dong, J Neuzil, H Blanchard, SJ Ralph Angiogenesis 14, 293-307, 2011 | 122 | 2011 |
