Complex multi-enhancer contacts captured by genome architecture mapping RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ... Nature 543 (7646), 519-524, 2017 | 740 | 2017 |
Dynamics of the 4D genome during in vivo lineage specification and differentiation AM Oudelaar, RA Beagrie, M Gosden, S de Ornellas, E Georgiades, ... Nature Communications 11 (1), 1-12, 2020 | 102 | 2020 |
Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types A Miar, E Arnaiz, E Bridges, S Beedie, AP Cribbs, DJ Downes, ... Cancer Research 80 (23), 5245-5256, 2020 | 73 | 2020 |
Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription RA Beagrie, A Pombo BioEssays 38 (9), 881-893, 2016 | 55 | 2016 |
Research data preservation and access: The views of researchers N Beagrie, R Beagrie, I Rowlands Ariadne, 2009 | 50 | 2009 |
Enhancers predominantly regulate gene expression during differentiation via transcription initiation MSC Larke, R Schwessinger, T Nojima, J Telenius, RA Beagrie, ... Molecular Cell 81 (5), 983-997. e7, 2021 | 43 | 2021 |
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale DJ Downes, RA Beagrie, ME Gosden, J Telenius, SJ Carpenter, ... Nature communications 12 (1), 1-15, 2021 | 37 | 2021 |
Reactivation of a developmentally silenced embryonic globin gene AJ King, D Songdej, DJ Downes, RA Beagrie, S Liu, M Buckley, P Hua, ... Nature Communications 12 (1), 1-15, 2021 | 35 | 2021 |
The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization AM Oudelaar, RA Beagrie, MT Kassouf, DR Higgs Current Opinion in Genetics & Development 67, 18-24, 2021 | 29 | 2021 |
Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C RA Beagrie, CJ Thieme, C Annunziatella, C Baugher, Y Zhang, ... Nature Methods, 1-11, 2023 | 22 | 2023 |
Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities C Scott, DJ Downes, JM Brown, R Beagrie, AA Olijnik, M Gosden, ... Haematologica, 2020 | 15 | 2020 |
Cell cycle: continuous chromatin changes RA Beagrie, A Pombo Nature 547 (7661), 34-36, 2017 | 14 | 2017 |
Multiplex-GAM: genome-wide identification of chromatin contacts yields insights not captured by Hi-C RA Beagrie, CJ Thieme, C Annunziatella, C Baugher, Y Zhang, ... bioRxiv, 2020.07. 31.230284, 2021 | 13 | 2021 |
Scalable in vitro production of defined mouse erythroblasts HS Francis, CL Harold, RA Beagrie, AJ King, ME Gosden, JW Blayney, ... Plos one 17 (1), e0261950, 2022 | 11 | 2022 |
Making connections: enhancers in cellular differentiation JC Herrmann, RA Beagrie, JR Hughes Trends in Genetics, 2021 | 11 | 2021 |
Gene silencing dynamics are modulated by transiently active regulatory elements MW Vermunt, J Luan, Z Zhang, AJ Thrasher, A Huang, MS Saari, ... Molecular cell 83 (5), 715-730. e6, 2023 | 10 | 2023 |
Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks MM Jung, S Shen, GA Botten, T Olender, KR Katsumura, KD Johnson, ... The Journal of Clinical Investigation 133 (7), 2023 | 7 | 2023 |
Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation RJ Stolper, FH Tsang, E Georgiades, LLP Hanssen, DJ Downes, ... bioRxiv, 2023.09. 07.556660, 2023 | 4 | 2023 |
GAMtools: an automated pipeline for analysis of Genome Architecture Mapping data RA Beagrie, M Schueler bioRxiv, 114710, 2017 | 3 | 2017 |
Examining topological domain influence on enhancer function RA Beagrie, A Pombo Developmental Cell 39 (5), 523-524, 2016 | 2 | 2016 |