A role for mitochondria in NLRP3 inflammasome activation R Zhou, AS Yazdi, P Menu, J Tschopp Nature 469 (7329), 221-225, 2011 | 5640 | 2011 |
Thioredoxin-interacting protein links oxidative stress to inflammasome activation R Zhou, A Tardivel, B Thorens, I Choi, J Tschopp Nature immunology 11 (2), 136-140, 2010 | 2947 | 2010 |
DAMP-sensing receptors in sterile inflammation and inflammatory diseases T Gong, L Liu, W Jiang, R Zhou Nature Reviews Immunology 20 (2), 95-112, 2020 | 1465 | 2020 |
The NLRP3 inflammasome: a sensor for metabolic danger? K Schroder, R Zhou, J Tschopp Science 327 (5963), 296-300, 2010 | 1288 | 2010 |
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome Y Yan, W Jiang, L Liu, X Wang, C Ding, Z Tian, R Zhou Cell 160 (1), 62-73, 2015 | 1016 | 2015 |
NLRP3 inflammasome activation and cell death Y Huang, W Xu, R Zhou Cellular & molecular immunology 18 (9), 2114-2127, 2021 | 935 | 2021 |
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation Y Yan, W Jiang, T Spinetti, A Tardivel, R Castillo, C Bourquin, G Guarda, ... Immunity 38 (6), 1154-1163, 2013 | 777 | 2013 |
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders H Jiang, H He, Y Chen, W Huang, J Cheng, J Ye, A Wang, J Tao, C Wang, ... Journal of Experimental Medicine 214 (11), 3219-3238, 2017 | 653 | 2017 |
Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity H He, H Jiang, Y Chen, J Ye, A Wang, C Wang, Q Liu, G Liang, X Deng, ... Nature communications 9 (1), 2550, 2018 | 619 | 2018 |
The lncRNA Neat1 promotes activation of inflammasomes in macrophages P Zhang, L Cao, R Zhou, X Yang, M Wu Nature communications 10 (1), 1495, 2019 | 433 | 2019 |
Tranilast directly targets NLRP 3 to treat inflammasome‐driven diseases Y Huang, H Jiang, Y Chen, X Wang, Y Yang, J Tao, X Deng, G Liang, ... EMBO molecular medicine 10 (4), e8689, 2018 | 433 | 2018 |
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway P Menu, A Mayor, R Zhou, A Tardivel, H Ichijo, K Mori, J Tschopp Cell death & disease 3 (1), e261-e261, 2012 | 383 | 2012 |
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway X Wang, W Jiang, Y Yan, T Gong, J Han, Z Tian, R Zhou Nature immunology 15 (12), 1126-1133, 2014 | 355 | 2014 |
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation T Tang, X Lang, C Xu, X Wang, T Gong, Y Yang, J Cui, L Bai, J Wang, ... Nature communications 8 (1), 202, 2017 | 332 | 2017 |
RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice Z Huang, SQ Wu, Y Liang, X Zhou, W Chen, L Li, J Wu, Q Zhuang, ... Cell host & microbe 17 (2), 229-242, 2015 | 286 | 2015 |
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity J Geng, X Sun, P Wang, S Zhang, X Wang, H Wu, L Hong, C Xie, X Li, ... Nature immunology 16 (11), 1142-1152, 2015 | 263 | 2015 |
Orchestration of NLRP3 inflammasome activation by ion fluxes T Gong, Y Yang, T Jin, W Jiang, R Zhou Trends in immunology 39 (5), 393-406, 2018 | 231 | 2018 |
Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis X Yao, C Zhang, Y Xing, G Xue, Q Zhang, F Pan, G Wu, Y Hu, Q Guo, A Lu, ... Nature communications 8 (1), 1896, 2017 | 181 | 2017 |
Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes W Jiang, X Wang, B Zeng, L Liu, A Tardivel, H Wei, J Han, HR MacDonald, ... Journal of Experimental Medicine 210 (11), 2465-2476, 2013 | 180 | 2013 |
TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity X Lang, T Tang, T Jin, C Ding, R Zhou, W Jiang Journal of experimental medicine 214 (2), 459-473, 2017 | 160 | 2017 |