| Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling PR Shepherd, DJ Withers, K Siddle Biochemical Journal 333 (3), 471-490, 1998 | 1269 | 1998 |
| Signalling by insulin and IGF receptors: supporting acts and new players K Siddle Journal of molecular endocrinology 47 (1), R1-R10, 2011 | 601 | 2011 |
| Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin-and antibody-stimulated glucose uptake and receptor kinase activity. Y Ebina, E Araki, M Taira, F Shimada, M Mori, CS Craik, K Siddle, ... Proceedings of the National Academy of Sciences 84 (3), 704-708, 1987 | 553 | 1987 |
| Tumor necrosis factor-α induces apoptosis of human adipose cells JB Prins, CU Niesler, CM Winterford, NA Bright, K Siddle, S O'Rahilly, ... Diabetes 46 (12), 1939-1944, 1997 | 488 | 1997 |
| Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins WJ Sobey, SF Beer, CA Carrington, PMS Clark, BH Frank, IP Gray, ... Biochemical Journal 260 (2), 535-541, 1989 | 423 | 1989 |
| Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and … EM BAILYES, BT NAVÉ, MA SOOS, SR ORR, AC HAYWARD, K SIDDLE Biochemical Journal 327 (1), 209-215, 1997 | 362 | 1997 |
| Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity MA Soos, CE Field, K Siddle Biochemical Journal 290 (2), 419-426, 1993 | 347 | 1993 |
| Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of … PR Shepherd, BT Nave, K Siddle Biochemical Journal 305 (1), 25-28, 1995 | 330 | 1995 |
| Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second … G Pandini, R Vigneri, A Costantino, F Frasca, A Ippolito, ... Clinical Cancer Research 5 (7), 1935-1944, 1999 | 325 | 1999 |
| Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and … S Benyoucef, KH Surinya, D Hadaschik, K Siddle Biochemical Journal 403 (3), 603-613, 2007 | 257 | 2007 |
| Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells MA Soos, J Whittaker, R Lammers, A Ullrich, K Siddle Biochemical Journal 270 (2), 383-390, 1990 | 257 | 1990 |
| Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors … MA Soos, K Siddle Biochemical Journal 263 (2), 553-563, 1989 | 249 | 1989 |
| Immunoassay of antigens GC Forrest, PRP Salacinski, K Siddle US Patent 4,659,678, 1987 | 235 | 1987 |
| Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor MA Soos, K Siddle, MD Baron, JM Heward, JP Luzio, J Bellatin, ... Biochemical Journal 235 (1), 199-208, 1986 | 235 | 1986 |
| Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors K Siddle, B Ursø, CA Niesler, DL Cope, L Molina, KH Surinya, MA Soos Biochemical Society Transactions 29 (4), 513-525, 2001 | 219 | 2001 |
| Grb10 and Grb14: enigmatic regulators of insulin action–and more? LJ Holt, K Siddle Biochemical Journal 388 (2), 393-406, 2005 | 214 | 2005 |
| Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances K Siddle Frontiers in endocrinology 3, 34, 2012 | 192 | 2012 |
| Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes D Ferland-McCollough, DS Fernandez-Twinn, IG Cannell, H David, ... Cell Death & Differentiation 19 (6), 1003-1012, 2012 | 181 | 2012 |
| The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies. PA Wilden, K Siddle, E Haring, JM Backer, MF White, CR Kahn Journal of Biological Chemistry 267 (19), 13719-13727, 1992 | 174 | 1992 |
| Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes BT NAVÉ, AC HAYWARD, K SIDDLE, PR SHEPHERD Biochemical Journal 318 (1), 55-60, 1996 | 166 | 1996 |
