Mapping human microbiome drug metabolism by gut bacteria and their genes M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman Nature 570 (7762), 462-467, 2019 | 986 | 2019 |
Separating host and microbiome contributions to drug pharmacokinetics and toxicity M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman Science 363 (6427), eaat9931, 2019 | 389 | 2019 |
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ... Cancer cell 39 (3), 288-293, 2021 | 118 | 2021 |
CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data R Wegmann, M Neri, S Schuierer, B Bilican, H Hartkopf, F Nigsch, F Mapa, ... Genome biology 20, 1-21, 2019 | 54 | 2019 |
Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma K Kropivsek, P Kachel, S Goetze, R Wegmann, Y Festl, Y Severin, ... Nature cancer 4 (5), 734-753, 2023 | 32 | 2023 |
A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs S Cherkaoui, S Durot, J Bradley, S Critchlow, S Dubuis, MM Masiero, ... Molecular Systems Biology 18 (11), e11033, 2022 | 21 | 2022 |
ROS induction targets persister cancer cells with low metabolic activity in NRAS-mutated melanoma OM Eichhoff, CI Stoffel, J Käsler, L Briker, P Turko, G Karsai, N Zila, ... Cancer Research 83 (7), 1128-1146, 2023 | 15 | 2023 |
Separating host and microbiome contributions to drug pharmacokinetics and toxicity. Science 363: eaat9931 M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman | 11 | 2019 |
High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity S Lee, T Weiss, M Bühler, J Mena, Z Lottenbach, R Wegmann, M Sun, ... Nature Medicine 30 (11), 3196-3208, 2024 | 8 | 2024 |
Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia R Wegmann, X Bonilla, R Casanova, S Chevrier, R Coelho, C Esposito, ... Nature Communications 15 (1), 9402, 2024 | 3 | 2024 |
Targeting tumour-intrinsic neural vulnerabilities of glioblastoma S Lee, T Weiss, M Bühler, J Mena, Z Lottenbach, R Wegmann, M Sun, ... bioRxiv, 2022.10. 07.511321, 2022 | 3 | 2022 |
Molecular and functional landscape of malignant serous effusions for precision oncology R Wegmann, L Bankel, Y Festl, K Lau, S Lee, F Arnold, V Cappelletti, ... Nature Communications 15 (1), 8544, 2024 | 1 | 2024 |
Epithelial-mesenchymal transition is the main driver of intrinsic metabolism in cancer cell lines S Cherkaoui, S Durot, J Bradley, S Critchlow, S Dubuis, MM Masiero, ... bioRxiv, 2021.11. 02.466992, 2021 | 1 | 2021 |
DDDR-05. SPATIALLY RESOLVED DRUG SENSITIVITY PROFILING IN GLIOBLASTOMA A Buck, S Lee, R Wegmann, J Mena, F Vasella, J Friesen, L Regli, ... Neuro-Oncology 26 (Supplement_8), viii126-viii126, 2024 | | 2024 |
P01. 13. B SPATIALLY RESOLVED FUNCTIONAL PROFILING FOR GLIOBLASTOMA A Buck, S Lee, R Wegmann, J Mena, F Vasella, J Friesen, L Regli, ... Neuro-Oncology 26 (Supplement_5), v33-v33, 2024 | | 2024 |
Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia.: Derived single-cell datasets: scRNA-seq, CyTOF B Snijder, R Wegmann ETH Zurich, 2024 | | 2024 |
The cellular hierarchy of acute myeloid leukemia informs personalized treatment Y Severin, Y Festl, TM Benoit, R Wegmann, BD Hale, M Roiss, ... medRxiv, 2024.07. 24.24310768, 2024 | | 2024 |
DDDR-24. SINGLE-CELL FUNCTIONAL TISSUE PROFILING IDENTIFIES PROMISING CANDIDATES FOR DRUG REPURPOSING AGAINST GLIOBLASTOMA T Weiss, S Lee, M Buehler, J Mena, Z Lottenbach, R Wegmann, M Bihl, ... Neuro-Oncology 25 (Suppl 5), v110, 2023 | | 2023 |
Long-term history dependence of growth rates of E. coli after nutrient shifts D Christodoulou, A Mukherjee, R Wegmann, A Pagano, V Sharma, ... bioRxiv, 2023 | | 2023 |
Functional and molecular tumor profiling for precision oncology R Wegmann ETH Zurich, 2023 | | 2023 |