The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes TP Gu, F Guo, H Yang, HP Wu, GF Xu, W Liu, ZG Xie, L Shi, X He, S Jin, ... Nature 477 (7366), 606-610, 2011 | 1345 | 2011 |
The DNA methylation landscape of human early embryos H Guo, P Zhu, L Yan, R Li, B Hu, Y Lian, J Yan, X Ren, S Lin, J Li, X Jin, ... Nature 511 (7511), 606-610, 2014 | 1027 | 2014 |
The transcriptome and DNA methylome landscapes of human primordial germ cells F Guo, L Yan, H Guo, L Li, B Hu, Y Zhao, J Yong, Y Hu, X Wang, Y Wei, ... Cell 161 (6), 1437-1452, 2015 | 627 | 2015 |
Single-cell RNA-seq analysis maps development of human germline cells and gonadal niche interactions L Li, J Dong, L Yan, J Yong, X Liu, Y Hu, X Fan, X Wu, H Guo, X Wang, ... Cell Stem Cell 20 (6), 858-873, 2017 | 545 | 2017 |
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis C Zhou, Y Sun, R Yan, Y Liu, E Zuo, C Gu, L Han, Y Wei, X Hu, R Zeng, ... Nature 571 (7764), 275-278, 2019 | 466 | 2019 |
Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote F Guo, X Li, D Liang, T Li, P Zhu, H Guo, X Wu, L Wen, TP Gu, B Hu, ... Cell Stem Cell 15 (4), 447-458, 2014 | 450 | 2014 |
Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming X Hu, L Zhang, SQ Mao, Z Li, J Chen, RR Zhang, HP Wu, J Gao, F Guo, ... Cell Stem Cell 14 (4), 512-522, 2014 | 375 | 2014 |
Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells F Guo, L Li, J Li, X Wu, B Hu, P Zhu, L Wen, F Tang Cell Research 27 (8), 967-988, 2017 | 351 | 2017 |
Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing H Guo, P Zhu, F Guo, X Li, X Wu, X Fan, L Wen, F Tang Nature Protocols 10 (5), 645-659, 2015 | 194 | 2015 |
Single-cell multi-omics sequencing of human early embryos L Li, F Guo, Y Gao, Y Ren, P Yuan, L Yan, R Li, Y Lian, J Li, B Hu, J Gao, ... Nature Cell Biology 20 (7), 847-858, 2018 | 176 | 2018 |
Integrative single-cell analysis of transcriptome, DNA methylome and chromatin accessibility in mouse oocytes C Gu, S Liu, Q Wu, L Zhang, F Guo Cell Research 29 (2), 110-123, 2019 | 148 | 2019 |
DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells H Guo, B Hu, L Yan, J Yong, Y Wu, Y Gao, F Guo, Y Hou, X Fan, J Dong, ... Cell Research 27 (2), 165-183, 2017 | 131 | 2017 |
Gadd45a promotes DNA demethylation through TDG Z Li, TP Gu, AR Weber, JZ Shen, BZ Li, ZG Xie, R Yin, F Guo, X Liu, ... Nucleic Acids Research 43 (8), 3986-3997, 2015 | 113 | 2015 |
Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing R Yan, C Gu, D You, Z Huang, J Qian, Q Yang, X Cheng, L Zhang, ... Cell Stem Cell 28 (9), 1641-1656, 2021 | 96 | 2021 |
Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development R Yan, X Cheng, C Gu, Y Xu, X Long, J Zhai, F Sun, J Qian, Y Du, H Wang, ... Nature Genetics 55 (1), 130–143, 2023 | 62 | 2023 |
Epigenomic landscape of human fetal brain, heart, and liver L Yan, H Guo, B Hu, R Li, J Yong, Y Zhao, X Zhi, X Fan, F Guo, X Wang, ... Journal of Biological Chemistry 291 (9), 4386-4398, 2016 | 59 | 2016 |
Primate gastrulation and early organogenesis at single-cell resolution J Zhai, J Guo, H Wan, L Qi, L Liu, Z Xiao, L Yan, DA Schmitz, Y Xu, D Yu, ... Nature 612 (7941), 732-738, 2022 | 55 | 2022 |
Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements CE Rutledge, HT Lau, H Mangan, LL Hardy, O Sunnotel, F Guo, ... PLoS ONE 9 (2), e88385, 2014 | 32 | 2014 |
The essential role of Mbd5 in the regulation of somatic growth and glucose homeostasis in mice Y Du, B Liu, F Guo, GF Xu, Y Ding, Y Liu, X Sun, GL Xu PLoS ONE 7 (10), e47358, 2012 | 32 | 2012 |
Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture J Zhai, Y Xu, H Wan, R Yan, J Guo, R Skory, L Yan, X Wu, F Sun, G Chen, ... Cell 186 (10), 2078-2091. e18, 2023 | 31 | 2023 |