| TGF-β signaling in tumor suppression and cancer progression R Derynck, RJ Akhurst, A Balmain Nature genetics 29 (2), 117-129, 2001 | 3142 | 2001 |
| Targeting the TGFβ signalling pathway in disease RJ Akhurst, A Hata Nature reviews Drug discovery 11 (10), 790-811, 2012 | 1787 | 2012 |
| Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice MC Dickson, JS Martin, FM Cousins, AB Kulkarni, S Karlsson, RJ Akhurst Development 121 (6), 1845-1854, 1995 | 1364 | 1995 |
| TGF-β signaling in cancer–a double-edged sword RJ Akhurst, R Derynck Trends in cell biology 11 (11), S44-S51, 2001 | 1227 | 2001 |
| TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice W Cui, DJ Fowlis, S Bryson, E Duffie, H Ireland, A Balmain, RJ Akhurst Cell 86 (4), 531-542, 1996 | 833 | 1996 |
| TGFβ biology in cancer progression and immunotherapy R Derynck, SJ Turley, RJ Akhurst Nature reviews Clinical oncology 18 (1), 9-34, 2021 | 699 | 2021 |
| Embryonic gene expression patterns of TGF β1, β2 and β3 suggest different developmental functions in vivo FA Millan, F Denhez, P Kondaiah, RJ Akhurst Development 111 (1), 131-143, 1991 | 648 | 1991 |
| Differentiation plasticity regulated by TGF-β family proteins in development and disease R Derynck, RJ Akhurst Nature cell biology 9 (9), 1000-1004, 2007 | 547 | 2007 |
| Complexities of TGF-β targeted cancer therapy EC Connolly, J Freimuth, RJ Akhurst International journal of biological sciences 8 (7), 964, 2012 | 450 | 2012 |
| Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action SA Lehnert, RJ Akhurst Development 104 (2), 263-273, 1988 | 443 | 1988 |
| Metastasis is driven by sequential elevation of H-ras and Smad2 levels M Oft, RJ Akhurst, A Balmain Nature cell biology 4 (7), 487-494, 2002 | 424 | 2002 |
| TGF-β-induced activation of mTOR complex 2 drives epithelial–mesenchymal transition and cell invasion S Lamouille, E Connolly, JW Smyth, RJ Akhurst, R Derynck Journal of cell science 125 (5), 1259-1273, 2012 | 387 | 2012 |
| Differential expression of TGF beta isoforms in murine palatogenesis DR Fitzpatrick, F Denhez, P Kondaiah, RJ Akhurst Development 109 (3), 585-595, 1990 | 352 | 1990 |
| Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis RJ Akhurst, F Fee, A Balmaint Nature 331 (6154), 363-365, 1988 | 350 | 1988 |
| TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis RJ Akhurst, SA Lehnert, A Faissner, E Duffie Development 108 (4), 645-656, 1990 | 310 | 1990 |
| Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. G Portella, SA Cumming, J Liddell, W Cui, H Ireland, RJ Akhurst, ... Cell growth & differentiation: the molecular biology journal of the American …, 1998 | 280 | 1998 |
| Transforming growth factor-β in breast cancer: too much, too late MH Barcellos-Hoff, RJ Akhurst Breast cancer research 11, 1-6, 2009 | 262 | 2009 |
| TGFβ1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo F Bouquet, A Pal, KA Pilones, S Demaria, B Hann, RJ Akhurst, JS Babb, ... Clinical Cancer Research 17 (21), 6754-6765, 2011 | 261 | 2011 |
| Genetic events and the role of TGFβ in epithelial tumour progression RJ Akhurst, A Balmain The Journal of Pathology 187 (1), 82-90, 1999 | 231 | 1999 |
| Mapping of a major genetic modifier of embryonic lethality in TGFβ1 knockout mice M Bonyadi, SAB Rusholme, FM Cousins, HC Su, CA Biron, M Farrall, ... Nature genetics 15 (2), 207-211, 1997 | 227 | 1997 |
