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Amanda E. Hargrove
Amanda E. Hargrove
Professor of Chemistry, University of Toronto
Верификована је имејл адреса на utoronto.ca - Почетна страница
Наслов
Навело
Навело
Година
Artificial receptors for the recognition of phosphorylated molecules
AE Hargrove, S Nieto, T Zhang, JL Sessler, EV Anslyn
Chemical reviews 111 (11), 6603-6782, 2011
6912011
Targeting RNA with small molecules: from fundamental principles towards the clinic
JP Falese, A Donlic, AE Hargrove
Chemical Society Reviews 50 (4), 2224-2243, 2021
1762021
Algorithms for the determination of binding constants and enantiomeric excess in complex host: guest equilibria using optical measurements
AE Hargrove, Z Zhong, JL Sessler, EV Anslyn
New Journal of Chemistry 34 (2), 348-354, 2010
1642010
Targeting RNA in mammalian systems with small molecules
A Donlic, AE Hargrove
Wiley Interdisciplinary Reviews: RNA 9 (4), e1477, 2018
1362018
Probing Intramolecular B−N Interactions in Ortho-Aminomethyl Arylboronic Acids
BE Collins, S Sorey, AE Hargrove, SH Shabbir, VM Lynch, EV Anslyn
The Journal of organic chemistry 74 (11), 4055-4060, 2009
1232009
Discovery of small molecule ligands for MALAT1 by tuning an RNA‐binding scaffold
A Donlic, BS Morgan, JL Xu, A Liu, C Roble Jr, AE Hargrove
Angewandte Chemie International Edition 57 (40), 13242-13247, 2018
1172018
Discovery of key physicochemical, structural, and spatial properties of RNA‐targeted bioactive ligands
BS Morgan, JE Forte, RN Culver, Y Zhang, AE Hargrove
Angewandte Chemie International Edition 56 (43), 13498-13502, 2017
1162017
IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex
J Davila-Calderon, NN Patwardhan, LY Chiu, A Sugarman, Z Cai, ...
Nature communications 11 (1), 4775, 2020
922020
Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR
NN Patwardhan, LR Ganser, GJ Kapral, CS Eubanks, J Lee, ...
MedChemComm 8 (5), 1022-1036, 2017
922017
Fluorescent indicator displacement assays to identify and characterize small molecule interactions with RNA
SL Wicks, AE Hargrove
Methods 167, 3-14, 2019
902019
KDM1 class flavin‐dependent protein lysine demethylases
JM Burg, JE Link, BS Morgan, FJ Heller, AE Hargrove, DG McCafferty
Peptide Science 104 (4), 213-246, 2015
772015
R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes
BS Morgan, BG Sanaba, A Donlic, DB Karloff, JE Forte, Y Zhang, ...
ACS chemical biology 14 (12), 2691-2700, 2019
762019
Synthetic Receptors for Biomolecules: Design Principles and Applications
BD Smith
Royal Society of Chemistry, 2015
762015
Insights into the development of chemical probes for RNA
BS Morgan, JE Forte, AE Hargrove
Nucleic acids research 46 (16), 8025-8037, 2018
652018
Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide
JA Raskatov, NG Nickols, AE Hargrove, GK Marinov, B Wold, PB Dervan
Proceedings of the National Academy of Sciences 109 (40), 16041-16045, 2012
652012
Small molecule–RNA targeting: starting with the fundamentals
AE Hargrove
Chemical Communications 56 (94), 14744-14756, 2020
622020
Biochemical methods to investigate lncRNA and the influence of lncRNA: protein complexes on chromatin
EJ McFadden, AE Hargrove
Biochemistry 55 (11), 1615-1630, 2016
622016
Frameworks for targeting RNA with small molecules
AU Juru, AE Hargrove
Journal of Biological Chemistry 296, 2021
612021
Small molecule-based pattern recognition to classify RNA structure
CS Eubanks, JE Forte, GJ Kapral, AE Hargrove
Journal of the American Chemical Society 139 (1), 409-416, 2017
602017
Characterization and solubilization of pyrrole–imidazole polyamide aggregates
AE Hargrove, JA Raskatov, JL Meier, DC Montgomery, PB Dervan
Journal of medicinal chemistry 55 (11), 5425-5432, 2012
592012
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Чланци 1–20