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| Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression F Lan, RE Collins, R De Cegli, R Alpatov, JR Horton, X Shi, O Gozani, ... Nature 448 (7154), 718-722, 2007 | 506 | 2007 |
| The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix H Hashimoto, JR Horton, X Zhang, M Bostick, SE Jacobsen, X Cheng Nature 455 (7214), 826-829, 2008 | 496 | 2008 |
| Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases JR Horton, AK Upadhyay, HH Qi, X Zhang, Y Shi, X Cheng Nature structural & molecular biology 17 (1), 38-43, 2010 | 413 | 2010 |
| Structural basis for the product specificity of histone lysine methyltransferases X Zhang, Z Yang, SI Khan, JR Horton, H Tamaru, EU Selker, X Cheng Molecular cell 12 (1), 177-185, 2003 | 409 | 2003 |
| The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin FE Reyes-Turcu, JR Horton, JE Mullally, A Heroux, X Cheng, ... Cell 124 (6), 1197-1208, 2006 | 394 | 2006 |
| Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294 Y Chang, X Zhang, JR Horton, AK Upadhyay, A Spannhoff, J Liu, ... Nature structural & molecular biology 16 (3), 312-317, 2009 | 377 | 2009 |
| The ankyrin repeats of G9a and GLP histone methyltransferases are mono-and dimethyllysine binding modules RE Collins, JP Northrop, JR Horton, DY Lee, X Zhang, MR Stallcup, ... Nature structural & molecular biology 15 (3), 245-250, 2008 | 343 | 2008 |
| Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase X Zhang, H Tamaru, SI Khan, JR Horton, LJ Keefe, EU Selker, X Cheng Cell 111 (1), 117-127, 2002 | 334 | 2002 |
| Structural basis for the versatile and methylation-dependent binding of CTCF to DNA H Hashimoto, D Wang, JR Horton, X Zhang, VG Corces, X Cheng Molecular cell 66 (5), 711-720. e3, 2017 | 265 | 2017 |
| A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability PO Estève, Y Chang, M Samaranayake, AK Upadhyay, JR Horton, ... Nature structural & molecular biology 18 (1), 42-48, 2011 | 248 | 2011 |
| MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a Y Chang, L Sun, K Kokura, JR Horton, M Fukuda, A Espejo, V Izumi, ... Nature communications 2 (1), 533, 2011 | 187 | 2011 |
| Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia MB Pappalardi, K Keenan, M Cockerill, WA Kellner, A Stowell, C Sherk, ... Nature cancer 2 (10), 1002-1017, 2021 | 178 | 2021 |
| Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain SR Stowell, CM Arthur, KA Slanina, JR Horton, DF Smith, RD Cummings Journal of Biological Chemistry 283 (29), 20547-20559, 2008 | 176 | 2008 |
| UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications H Hashimoto, JR Horton, X Zhang, X Cheng Epigenetics 4 (1), 8-14, 2009 | 159 | 2009 |
| SETD3 is an actin histidine methyltransferase that prevents primary dystocia AW Wilkinson, J Diep, S Dai, S Liu, YS Ooi, D Song, TM Li, JR Horton, ... Nature 565 (7739), 372-376, 2019 | 156 | 2019 |
| Structures of Hha I methyltransferase complexed with substrates containing mismatches at the target base M O'Gara, JR Horton, RJ Roberts, X Cheng Nature structural biology 5 (10), 872-877, 1998 | 154 | 1998 |
| Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase JR Horton, K Liebert, M Bekes, A Jeltsch, X Cheng Journal of molecular biology 358 (2), 559-570, 2006 | 150 | 2006 |
| Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase K Sawada, Z Yang, JR Horton, RE Collins, X Zhang, X Cheng Journal of Biological Chemistry 279 (41), 43296-43306, 2004 | 142 | 2004 |
| KDM5 histone demethylases repress immune response via suppression of STING L Wu, J Cao, WL Cai, SM Lang, JR Horton, DJ Jansen, ZZ Liu, JF Chen, ... PLoS biology 16 (8), e2006134, 2018 | 141 | 2018 |
Or Gozani, M.D., Ph.D.Morris Herzstein Professor of Biology, Stanford UniversityВерификована је имејл адреса на stanford.edu
