Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution S López, EL Lim, S Horswell, K Haase, A Huebner, M Dietzen, ... Nature genetics 52 (3), 283-293, 2020 | 228 | 2020 |
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ... Cancer Cell 39 (11), 1497-1518. e11, 2021 | 198 | 2021 |
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA C Abbosh, AM Frankell, T Harrison, J Kisistok, A Garnett, L Johnson, ... Nature 616 (7957), 553-562, 2023 | 185 | 2023 |
The evolution of lung cancer and impact of subclonal selection in TRACERx AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ... Nature 616 (7957), 525-533, 2023 | 177 | 2023 |
Genomic–transcriptomic evolution in lung cancer and metastasis C Martínez-Ruiz, JRM Black, C Puttick, MS Hill, J Demeulemeester, ... Nature 616 (7957), 543-552, 2023 | 125 | 2023 |
The evolution of non-small cell lung cancer metastases in TRACERx M Al Bakir, A Huebner, C Martínez-Ruiz, K Grigoriadis, TBK Watkins, ... Nature 616 (7957), 534-542, 2023 | 123 | 2023 |
Representative sequencing: unbiased sampling of solid tumor tissue K Litchfield, S Stanislaw, L Spain, LL Gallegos, A Rowan, D Schnidrig, ... Cell reports 31 (5), 2020 | 71 | 2020 |
Abstract CT023: Phylogenetic tracking and minimal residual disease detection using ctDNA in early-stage NSCLC: A lung TRACERx study C Abbosh, A Frankell, A Garnett, T Harrison, M Weichert, A Licon, ... Cancer Research 80 (16_Supplement), CT023-CT023, 2020 | 57 | 2020 |
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx T Karasaki, DA Moore, S Veeriah, C Naceur-Lombardelli, A Toncheva, ... Nature medicine 29 (4), 833-845, 2023 | 55 | 2023 |
Body composition and lung cancer-associated cachexia in TRACERx O Al-Sawaf, J Weiss, M Skrzypski, JM Lam, T Karasaki, F Zambrana, ... Nature medicine 29 (4), 846-858, 2023 | 54 | 2023 |
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways L Spain, A Coulton, I Lobon, A Rowan, D Schnidrig, STC Shepherd, ... Cancer Discovery 13 (6), 1364-1385, 2023 | 33 | 2023 |
An economical, quantitative, and robust protocol for high-throughput T cell receptor sequencing from tumor or blood I Uddin, K Joshi, T Oakes, JM Heather, C Swanton, TRACERx consortium, ... Cancer Immunosurveillance: Methods and Protocols, 15-42, 2019 | 19 | 2019 |
CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction K Grigoriadis, A Huebner, A Bunkum, E Colliver, AM Frankell, MS Hill, ... Nature Protocols 19 (1), 159-183, 2024 | 18 | 2024 |
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling S Hobor, M Al Bakir, CT Hiley, M Skrzypski, AM Frankell, B Bakker, ... Nature Communications 15 (1), 4871, 2024 | 12 | 2024 |
ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA A Huebner, JRM Black, F Sarno, R Pazo, I Juez, L Medina, ... Genome Medicine 15 (1), 27, 2023 | 7 | 2023 |
Whole genome doubling mitigates muller’s ratchet in cancer evolution S López, E Lim, A Huebner, M Dietzen, T Mourikis, TBK Watkins, ... bioRxiv, 513457, 2019 | 7 | 2019 |
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models RE Hynds, A Huebner, DR Pearce, MS Hill, AU Akarca, DA Moore, ... Nature Communications 15 (1), 4653, 2024 | 6 | 2024 |
Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer DR Pearce, AU Akarca, RPH De Maeyer, E Kostina, A Huebner, ... Frontiers in Oncology 13, 1156743, 2023 | 5 | 2023 |
Genomic evolution of non-small cell lung cancer patient-derived xenograft models RE Hynds, A Huebner, DR Pearce, AU Akarca, DA Moore, S Ward, ... bioRxiv, 2023.01. 06.521078, 2023 | 5 | 2023 |
SnapShot: Tumor evolution A Huebner, M Dietzen, N McGranahan Cell 184 (6), 1650-1650. e1, 2021 | 5 | 2021 |