Прати
William A Denny
William A Denny
Distinguished Professor, The University of Auckland
Верификована је имејл адреса на auckland.ac.nz
Наслов
Навело
Навело
Година
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality
DA Chan, PD Sutphin, P Nguyen, S Turcotte, EW Lai, A Banh, ...
Science translational medicine 3 (94), 94ra70-94ra70, 2011
6152011
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor
DW Fry, AJ Bridges, WA Denny, A Doherty, KD Greis, JL Hicks, KE Hook, ...
Proceedings of the National Academy of Sciences 95 (20), 12022-12027, 1998
5671998
Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via …
WA Denny, GW Rewcastle, BC Baguley
Journal of medicinal chemistry 33 (2), 814-819, 1990
4421990
Tyrosine kinase inhibitors. 8. An unusually steep structure− activity relationship for analogues of 4-(3-bromoanilino)-6, 7-dimethoxyquinazoline (PD 153035), a potent inhibitor …
AJ Bridges, H Zhou, DR Cody, GW Rewcastle, A McMichael, ...
Journal of medicinal chemistry 39 (1), 267-276, 1996
4381996
Prodrug strategies in cancer therapy
WA Denny
European journal of medicinal chemistry 36 (7-8), 577-595, 2001
4362001
Acridine derivatives as chemotherapeutic agents
WA Denny
Current Medicinal Chemistry 9 (18), 1655-1665, 2002
3992002
Interactions of antitumor drugs with natural DNA: proton NMR study of binding mode and kinetics
J Feigon, WA Denny, W Leupin, DR Kearns
Journal of medicinal chemistry 27 (4), 450-465, 1984
3891984
Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino) quinazoline-and 4-(phenylamino) pyrido [3, 2-d] pyrimidine-6 …
JB Smaill, GW Rewcastle, JA Loo, KD Greis, OH Chan, EL Reyner, ...
Journal of medicinal chemistry 43 (7), 1380-1397, 2000
3812000
Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl) amino]-and 4-(phenylamino) quinazolines as potent adenosine 5'-triphosphate …
GW Rewcastle, WA Denny, AJ Bridges, H Zhou, DR Cody, A McMichael, ...
Journal of medicinal chemistry 38 (18), 3482-3487, 1995
3541995
DNA-intercalating ligands as anti-cancer drugs: prospects for future design.
WA Denny
Anti-cancer drug design 4 (4), 241-263, 1989
3481989
RETRACTED: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation
J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ...
Cancer research 69 (10), 4277-4285, 2009
3122009
Genotoxicity of non-covalent interactions: DNA intercalators
LR Ferguson, WA Denny
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 623 (1 …, 2007
3082007
A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy
S Turcotte, DA Chan, PD Sutphin, MP Hay, WA Denny, AJ Giaccia
Cancer cell 14 (1), 90-102, 2008
2992008
Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides
S Dissanayake, WA Denny, S Gamage, V Sarojini
Journal of Controlled Release 250, 62-76, 2017
2982017
Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d (ATATCGATAT)
J Feigon, W Leupin, WA Denny, DR Kearns
Biochemistry 22 (25), 5943-5951, 1983
2831983
Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring
BC Baguley, WA Denny, GJ Atwell, BF Cain
Journal of medicinal chemistry 24 (2), 170-177, 1981
2821981
Potential antitumor agents. 50. In vivo solid-tumor activity of derivatives of N-[2-(dimethylamino) ethyl] acridine-4-carboxamide
GJ Atwell, GW Rewcastle, BC Baguley, WA Denny
Journal of medicinal chemistry 30 (4), 664-669, 1987
2761987
Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104
AV Patterson, DM Ferry, SJ Edmunds, Y Gu, RS Singleton, K Patel, ...
Clinical Cancer Research 13 (13), 3922-3932, 2007
2712007
Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids
GW Rewcastle, GJ Atwell, L Zhuang, BC Baguley, WA Denny
Journal of medicinal chemistry 34 (1), 217-222, 1991
2701991
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
C Chaussade, GW Rewcastle, JD Kendall, WA Denny, K Cho, ...
Biochemical Journal 404 (3), 449-458, 2007
2652007
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