Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice Y Tao, M Mis, L Blazer, M Ustav, Z Steinhart, R Chidiac, E Kubarakos, ... Elife 8, e46134, 2019 | 92 | 2019 |
NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy K Miloudi, M Oubaha, C Ménard, A Dejda, V Guber, G Cagnone, ... Proceedings of the National Academy of Sciences 116 (10), 4538-4547, 2019 | 89 | 2019 |
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion A Abu-Thuraia, R Gauthier, R Chidiac, Y Fukui, RA Screaton, JP Gratton, ... Molecular and Cellular Biology, 2015 | 87 | 2015 |
AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network A Abu-Thuraia, MA Goyette, J Boulais, C Delliaux, C Apcher, C Schott, ... Nature communications 11 (1), 3586, 2020 | 70 | 2020 |
A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy R Chidiac, M Abedin, G Macleod, A Yang, PE Thibeault, LL Blazer, ... EMBO molecular medicine 13 (7), e13977, 2021 | 45 | 2021 |
eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity TL Smith, M Oubaha, G Cagnone, C Boscher, JS Kim, Y El Bakkouri, ... Cellular and Molecular Life Sciences 79 (1), 37, 2022 | 41 | 2022 |
Cell adhesion controlled by adhesion G protein–coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo–Dock MN Hernández-Vásquez, SR Adame-García, N Hamoud, R Chidiac, ... Journal of Biological Chemistry 292 (29), 12178-12191, 2017 | 38 | 2017 |
Comparative phosphoproteomics analysis of VEGF and angiopoietin-1 signaling reveals ZO-1 as a critical regulator of endothelial cell proliferation R Chidiac, Y Zhang, S Tessier, D Faubert, C Delisle, JP Gratton Molecular & Cellular Proteomics 15 (5), 1511-1525, 2016 | 31 | 2016 |
Hydrogels as a platform for stem cell delivery to the heart M Kurdi, R Chidiac, C Hoemann, F Zouein, C Zgheib, GW Booz Congestive heart failure 16 (3), 132-135, 2010 | 25 | 2010 |
Calyculin A reveals serine/threonine phosphatase protein phosphatase 1 as a regulatory nodal point in canonical signal transducer and activator of transcription 3 signaling of … C Zgheib, FA Zouein, R Chidiac, M Kurdi, GW Booz Journal of Interferon & Cytokine Research 32 (2), 87-94, 2012 | 21 | 2012 |
Modulation of Wnt–β-catenin signaling with antibodies: therapeutic opportunities and challenges S O'brien, R Chidiac, S Angers Trends in pharmacological sciences 44 (6), 354-365, 2023 | 16 | 2023 |
Endothelial NO Synthase-Dependent S-Nitrosylation of β-Catenin Prevents Its Association with TCF4 and Inhibits Proliferation of Endothelial Cells Stimulated by … Y Zhang, R Chidiac, C Delisle, JP Gratton Molecular and cellular biology 37 (12), e00089-17, 2017 | 16 | 2017 |
Wnt signaling in stem cells during development and cell lineage specification R Chidiac, S Angers Current Topics in Developmental Biology 153, 121-143, 2023 | 15 | 2023 |
CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein ABD Ouadda, Y He, V Calabrese, H Ishii, R Chidiac, JP Gratton, PP Roux, ... Oncotarget 9 (14), 11646, 2018 | 14 | 2018 |
Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice. Elife 8 Y Tao, M Mis, L Blazer, MJ Ustav, Z Steinhart, R Chidiac, E Kubarakos, ... | 5 | 2019 |
ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis Y El Bakkouri, R Chidiac, C Delisle, J Corriveau, G Cagnone, ... Nature Communications 15 (1), 4405, 2024 | 4 | 2024 |
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification A Yang, R Chidiac, E Russo, H Steenland, Q Pauli, R Bonin, LL Blazer, ... Development 151 (5), 2024 | 3 | 2024 |
A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans B Vanderperre, A Muraleedharan, MF Dorion, F Larroquette, ... bioRxiv, 2023.09. 29.560170, 2023 | 2 | 2023 |
Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation R Chidiac, A Yang, E Kubarakos, N Mikolajewicz, H Han, MP Almeida, ... Stem Cell Reports 20 (2), 2025 | | 2025 |
A GENOME-WIDE CRISPR/CAS9 SCREENING IDENTIFIES GENETIC MODIFIERS OF ΑLPHA SYNUCLEIN AGGREGATES UPTAKE B Vanderperre, A Muraleedharan, F Larroquette, R Chidiac, C Tardif, ... IBRO Neuroscience Reports 15, S459, 2023 | | 2023 |