| Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2360 | 2020 |
| Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 541 | 2021 |
| Human genetic and immunological determinants of critical COVID-19 pneumonia Q Zhang, P Bastard, A Cobat, JL Casanova Nature 603 (7902), 587-598, 2022 | 287 | 2022 |
| Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi, R Pescarmona, ... Science 379 (6632), eabo3627, 2022 | 119 | 2022 |
| Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia Q Zhang, D Matuozzo, J Le Pen, D Lee, L Moens, T Asano, J Bohlen, ... Journal of Experimental Medicine 219 (8), 2022 | 112 | 2022 |
| Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria J Rosain, AL Neehus, J Manry, R Yang, J Le Pen, W Daher, Z Liu, ... Cell 186 (3), 621-645. e33, 2023 | 63 | 2023 |
| Distinct antibody repertoires against endemic human coronaviruses in children and adults T Khan, M Rahman, F Al Ali, SSY Huang, M Ata, Q Zhang, P Bastard, ... JCI insight 6 (4), 2021 | 60 | 2021 |
| NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages Z Liu, C Wu, Y Pan, H Liu, X Wang, Y Yang, M Gu, Y Zhang, X Wang Science advances 5 (2), eaav0163, 2019 | 51 | 2019 |
| Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency TM Campbell, Z Liu, Q Zhang, M Moncada-Velez, LE Covill, P Zhang, ... Journal of Experimental Medicine 219 (7), 2022 | 45 | 2022 |
| NDR1 protein kinase promotes IL‐17‐and TNF‐α‐mediated inflammation by competitively binding TRAF3 C Ma, W Lin, Z Liu, W Tang, R Gautam, H Li, Y Qian, H Huang, X Wang EMBO reports 18 (4), 586-602, 2017 | 42 | 2017 |
| Protein phosphatase PP1 negatively regulates the Toll-like receptor-and RIG-I-like receptor-triggered production of type I interferon by inhibiting IRF3 phosphorylation at … M Gu, T Zhang, Z Liu, R Lai, D Xia, H Huang, X Wang Cellular signalling 26 (12), 2930-2939, 2014 | 42 | 2014 |
| RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity M Gu, Z Liu, R Lai, S Liu, W Lin, C Ouyang, S Ye, H Huang, X Wang The EMBO journal 35 (23), 2553-2565, 2016 | 38 | 2016 |
| Encephalitis and poor neuronal death–mediated control of herpes simplex virus in human inherited RIPK3 deficiency Z Liu, EJ Garcia Reino, O Harschnitz, H Guo, YH Chan, NV Khobrekar, ... Science immunology 8 (82), eade2860, 2023 | 27 | 2023 |
| Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop Z Liu, Q Qin, C Wu, H Li, J Shou, Y Yang, M Gu, C Ma, W Lin, Y Zou, ... Nature communications 9 (1), 2789, 2018 | 26 | 2018 |
| Inborn errors of TLR3-or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis J Chen, H Jing, A Martin-Nalda, P Bastard, JG Rivière, Z Liu, R Colobran, ... Journal of Experimental Medicine 218 (12), 2021 | 24 | 2021 |
| Raf kinase inhibitor protein preferentially promotes TLR3-triggered signaling and inflammation R Lai, M Gu, W Jiang, W Lin, P Xu, Z Liu, H Huang, H An, X Wang The Journal of Immunology 198 (10), 4086-4095, 2017 | 20 | 2017 |
| E3 ubiquitin ligase NEDD4L negatively regulates keratinocyte hyperplasia by promoting GP130 degradation H Liu, W Lin, Z Liu, Y Song, H Cheng, H An, X Wang EMBO reports 22 (5), e52063, 2021 | 19 | 2021 |
| Silencing of human phosphatidylethanolamine-binding protein 4 enhances rituximab-induced death and chemosensitization in B-cell lymphoma K Wang, Y Jiang, W Zheng, Z Liu, H Li, J Lou, M Gu, X Wang PLoS One 8 (2), e56829, 2013 | 17 | 2013 |
| Human TMEFF1 is a restriction factor for herpes simplex virus in the brain YH Chan, Z Liu, P Bastard, N Khobrekar, KM Hutchison, Y Yamazaki, ... Nature 632 (8024), 390-400, 2024 | 6 | 2024 |
| Distinct antibody repertoires against endemic human coronaviruses in children and adults T Khan, M Rahman, FA Ali, SSY Huang, M Ata, Q Zhang, P Bastard, Z Liu, ... bioRxiv, 2020.06. 21.163394, 2020 | 1 | 2020 |