| Dynamic imaging of LDH inhibition in tumors reveals rapid in vivo metabolic rewiring and vulnerability to combination therapy N Oshima, R Ishida, S Kishimoto, K Beebe, JR Brender, K Yamamoto, ... Cell reports 30 (6), 1798-1810. e4, 2020 | 111 | 2020 |
| Hydrogen sulfide inhibits hypoxia-but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau-and mitochondria-dependent manner S Kai, T Tanaka, H Daijo, H Harada, S Kishimoto, K Suzuki, S Takabuchi, ... Antioxidants & redox signaling 16 (3), 203-216, 2012 | 94 | 2012 |
| Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization JR Brender, S Kishimoto, H Merkle, G Reed, RE Hurd, AP Chen, ... Scientific reports 9 (1), 3410, 2019 | 89 | 2019 |
| Evaluation of oxygen dependence on in vitro and in vivo cytotoxicity of photoimmunotherapy using IR-700–antibody conjugates S Kishimoto, M Bernardo, K Saito, S Koyasu, JB Mitchell, PL Choyke, ... Free Radical Biology and Medicine 85, 24-32, 2015 | 57 | 2015 |
| Metabolic and physiologic imaging biomarkers of the tumor microenvironment predict treatment outcome with radiation or a hypoxia-activated prodrug in mice S Matsumoto, S Kishimoto, K Saito, Y Takakusagi, JP Munasinghe, ... Cancer research 78 (14), 3783-3792, 2018 | 49 | 2018 |
| Pulsed electron paramagnetic resonance imaging: applications in the studies of tumor physiology S Kishimoto, KI Matsumoto, K Saito, A Enomoto, S Matsumoto, JB Mitchell, ... Antioxidants & redox signaling 28 (15), 1378-1393, 2018 | 41 | 2018 |
| Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302 Y Takakusagi, S Matsumoto, K Saito, M Matsuo, S Kishimoto, ... PloS one 9 (9), e107995, 2014 | 41 | 2014 |
| Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13C MRSI HY Chen, AW Autry, JR Brender, S Kishimoto, MC Krishna, M Vareth, ... Magnetic resonance in medicine 84 (6), 3351-3365, 2020 | 38 | 2020 |
| In Vivo Application of Proton-Electron Double-Resonance Imaging S Kishimoto, MC Krishna, VV Khramtsov, H Utsumi, DJ Lurie Antioxidants & redox signaling 28 (15), 1345-1364, 2018 | 35 | 2018 |
| Hypoxia-activated prodrug evofosfamide treatment in pancreatic ductal adenocarcinoma xenografts alters the tumor redox status to potentiate radiotherapy S Kishimoto, JR Brender, GVR Chandramouli, Y Saida, K Yamamoto, ... Antioxidants & Redox Signaling 35 (11), 904-915, 2021 | 34 | 2021 |
| Molecular imaging of the tumor microenvironment reveals the relationship between tumor oxygenation, glucose uptake, and glycolysis in pancreatic ductal adenocarcinoma K Yamamoto, JR Brender, T Seki, S Kishimoto, N Oshima, R Choudhuri, ... Cancer research 80 (11), 2087-2093, 2020 | 29 | 2020 |
| Radiotherapy Synergizes with the Hypoxia-Activated Prodrug Evofosfamide: In Vitro and In Vivo Studies Y Takakusagi, S Kishimoto, S Naz, S Matsumoto, K Saito, CP Hart, ... Antioxidants & Redox Signaling 28 (2), 131-140, 2018 | 29 | 2018 |
| Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice S Kishimoto, JR Brender, DR Crooks, S Matsumoto, T Seki, N Oshima, ... Elife 8, e46312, 2019 | 28 | 2019 |
| Fentanyl activates hypoxia-inducible factor 1 in neuronal SH-SY5Y cells and mice under non-hypoxic conditions in a μ-opioid receptor-dependent manner H Daijo, S Kai, T Tanaka, T Wakamatsu, S Kishimoto, K Suzuki, H Harada, ... European journal of pharmacology 667 (1-3), 144-152, 2011 | 25 | 2011 |
| Hypoxia imaging as a guide for hypoxia-modulated and hypoxia-activated therapy JR Brender, Y Saida, N Devasahayam, MC Krishna, S Kishimoto Antioxidants & Redox Signaling 36 (1-3), 144-159, 2022 | 23 | 2022 |
| Molecular imaging of tumor photoimmunotherapy: Evidence of photosensitized tumor necrosis and hemodynamic changes S Kishimoto, N Oshima, K Yamamoto, J Munasinghe, ... Free Radical Biology and Medicine 116, 1-10, 2018 | 23 | 2018 |
| A multimodal molecular imaging study evaluates pharmacological alteration of the tumor microenvironment to improve radiation response Y Takakusagi, S Naz, K Takakusagi, M Ishima, H Murata, K Ohta, M Miura, ... Cancer research 78 (24), 6828-6837, 2018 | 22 | 2018 |
| Multimodal molecular imaging detects early responses to immune checkpoint blockade Y Saida, JR Brender, K Yamamoto, JB Mitchell, MC Krishna, S Kishimoto Cancer research 81 (13), 3693-3705, 2021 | 21 | 2021 |
| Trehalose as an alternative to glycerol as a glassing agent for in vivo DNP MRI JR Brender, S Kishimoto, GR Eaton, SS Eaton, Y Saida, J Mitchell, ... Magnetic resonance in medicine 85 (1), 42-48, 2021 | 18 | 2021 |
| Multimodality imaging identifies distinct metabolic profiles in vitro and in vivo MA Neveu, G De Preter, V Marchand, A Bol, JR Brender, K Saito, ... Neoplasia 18 (12), 742-752, 2016 | 17 | 2016 |
