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STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors L Deng, H Liang, M Xu, X Yang, B Burnette, A Arina, XD Li, H Mauceri, ... Immunity 41 (5), 843-852, 2014 | 1914 | 2014 |
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The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity SG Park, Z Jiang, ED Mortenson, L Deng, O Radkevich-Brown, X Yang, ... Cancer cell 18 (2), 160-170, 2010 | 629 | 2010 |
Host STING-dependent MDSC mobilization drives extrinsic radiation resistance H Liang, L Deng, Y Hou, X Meng, X Huang, E Rao, W Zheng, H Mauceri, ... Nature communications 8 (1), 1736, 2017 | 432 | 2017 |
Dendritic cells but not macrophages sense tumor mitochondrial DNA for cross-priming through signal regulatory protein α signaling MM Xu, Y Pu, D Han, Y Shi, X Cao, H Liang, X Chen, XD Li, L Deng, ... Immunity 47 (2), 363-373. e5, 2017 | 292 | 2017 |
Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection X Guo, J Qiu, T Tu, X Yang, L Deng, RA Anders, L Zhou, YX Fu Immunity 40 (1), 25-39, 2014 | 279 | 2014 |
Non-canonical NF-κB antagonizes STING sensor-mediated DNA sensing in radiotherapy Y Hou, H Liang, E Rao, W Zheng, X Huang, L Deng, Y Zhang, X Yu, M Xu, ... Immunity 49 (3), 490-503. e4, 2018 | 220 | 2018 |
cGAS-STING–mediated DNA sensing maintains CD8+ T cell stemness and promotes antitumor T cell therapy W Li, L Lu, J Lu, X Wang, C Yang, J Jin, L Wu, X Hong, F Li, D Cao, ... Science translational medicine 12 (549), eaay9013, 2020 | 195 | 2020 |
Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell–mediated killing H Liang, L Deng, S Chmura, B Burnette, N Liadis, T Darga, MA Beckett, ... The Journal of Immunology 190 (11), 5874-5881, 2013 | 187 | 2013 |
Lymphotoxin regulates commensal responses to enable diet-induced obesity V Upadhyay, V Poroyko, T Kim, S Devkota, S Fu, D Liu, AV Tumanov, ... Nature immunology 13 (10), 947-953, 2012 | 160 | 2012 |
Accumulation of Foxp3+ T Regulatory Cells in Draining Lymph Nodes Correlates with Disease Progression and Immune Suppression in Colorectal Cancer Patients L Deng, H Zhang, Y Luan, J Zhang, Q Xing, S Dong, X Wu, M Liu, S Wang Clinical Cancer Research 16 (16), 4105-4112, 2010 | 160 | 2010 |
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation Y Yang, M Wu, D Cao, C Yang, J Jin, L Wu, X Hong, W Li, L Lu, J Li, ... Science advances 7 (41), eabf6290, 2021 | 135 | 2021 |
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Radiation and anti-PD-L1 antibody combinatorial therapy induces T cell-mediated depletion of myeloid-derived suppressor cells and tumor regression L Deng, H Liang, B Burnette, ralph weicheslbaum, YX Fu Oncoimmunology 3 (4), e28499, 2014 | 92 | 2014 |
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From DNA damage to nucleic acid sensing: a strategy to enhance radiation therapy L Deng, H Liang, S Fu, RR Weichselbaum, YX Fu Clinical Cancer Research 22 (1), 20-25, 2016 | 91 | 2016 |
Lister strain of vaccinia virus armed with endostatin–angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer JR Tysome, A Briat, G Alusi, F Cao, D Gao, J Yu, P Wang, S Yang, Z Dong, ... Gene therapy 16 (10), 1223-1233, 2009 | 84 | 2009 |
SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function Z Hu, XL Teng, T Zhang, X Yu, R Ding, J Yi, L Deng, Z Wang, Q Zou Molecular cell 81 (5), 940-952. e5, 2021 | 69 | 2021 |