| Addressing kinase-independent functions of Fak via PROTAC-mediated degradation PM Cromm, KTG Samarasinghe, J Hines, CM Crews Journal of the American Chemical Society 140 (49), 17019-17026, 2018 | 270 | 2018 |
| Reversible Spatiotemporal Control of Induced Protein Degradation by Bistable photoPROTACs EC Patrick Pfaff, Kusal T. G. Samarasinghe, Craig M. Crews ACS Central Science, 2019 | 259* | 2019 |
| Targeted protein degradation: A promise for undruggable proteins KTG Samarasinghe, CM Crews Cell chemical biology 28 (7), 934-951, 2021 | 193 | 2021 |
| Targeted degradation of transcription factors by TRAFTACs: transcription factor targeting chimeras KTG Samarasinghe, S Jaime-Figueroa, M Burgess, DA Nalawansha, ... Cell chemical biology 28 (5), 648-661. e5, 2021 | 140 | 2021 |
| Mutant-selective degradation by BRAF-targeting PROTACs S Alabi, S Jaime-Figueroa, Z Yao, Y Gao, J Hines, KTG Samarasinghe, ... Nature communications 12 (1), 920, 2021 | 118 | 2021 |
| Metabolic synthesis of clickable glutathione for chemoselective detection of glutathionylation KTG Samarasinghe, DNP Munkanatta Godage, GC VanHecke, YH Ahn Journal of the American Chemical Society 136 (33), 11566-11569, 2014 | 60 | 2014 |
| SMYD2 glutathionylation contributes to degradation of sarcomeric proteins DNP Munkanatta Godage, GC VanHecke, KTG Samarasinghe, HZ Feng, ... Nature communications 9 (1), 4341, 2018 | 39 | 2018 |
| A clickable glutathione approach for identification of protein glutathionylation in response to glucose metabolism KTG Samarasinghe, DNPM Godage, Y Zhou, FT Ndombera, ... Molecular BioSystems 12 (8), 2471-2480, 2016 | 39 | 2016 |
| OligoTRAFTACs: a generalizable method for transcription factor degradation KTG Samarasinghe, E An, MA Genuth, L Chu, SA Holley, CM Crews RSC Chemical Biology 3 (9), 1144-1153, 2022 | 33 | 2022 |
| Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation Y Zhang, S Dayalan Naidu, K Samarasinghe, GC Van Hecke, A Pheely, ... British journal of cancer 110 (1), 71-82, 2014 | 32 | 2014 |
| Double-barreled CRISPR technology as a novel treatment strategy for COVID-19 DA Nalawansha, KTG Samarasinghe ACS Pharmacology & Translational Science 3 (5), 790-800, 2020 | 28 | 2020 |
| Clickable glutathione using tetrazine-alkene bioorthogonal chemistry for detecting protein glutathionylation DN Kekulandara, KTG Samarasinghe, DNPM Godage, YH Ahn Organic & biomolecular chemistry 14 (46), 10886-10893, 2016 | 28 | 2016 |
| Synthesizing clickable glutathione by glutathione synthetase mutant for detecting protein glutathionylation KTG Samarasinghe, YH Ahn Synlett 26 (03), 285-293, 2015 | 14 | 2015 |
| Identification and quantification of glutathionylated cysteines under ischemic stress M Yapa Abeywardana, KTG Samarasinghe, D Munkanatta Godage, ... Journal of proteome research 20 (9), 4529-4542, 2021 | 10 | 2021 |
| Protein phosphatase PP2Cα S-glutathionylation regulates cell migration DSK Kukulage, KTG Samarasinghe, NNJM Don, MC Shivamadhu, ... Journal of Biological Chemistry 300 (10), 2024 | 1 | 2024 |
| Development Of Chemical Tools To Investigate Protein S-Glutathionylation In Response To Metabolic Alteration KTG Samarasinghe | | 2017 |
