| Two strategies to engineer flexible loops for improved enzyme thermostability H Yu, Y Yan, C Zhang, PA Dalby Scientific reports 7 (1), 1-15, 2017 | 203 | 2017 |
| Computational design to reduce conformational flexibility and aggregation rates of an antibody fab fragment C Zhang, M Samad, H Yu, N Chakroun, D Hilton, PA Dalby Molecular pharmaceutics 15 (8), 3079-3092, 2018 | 38 | 2018 |
| Identification of Protein–Excipient Interaction Hotspots Using Computational Approaches TS Barata, C Zhang, PA Dalby, S Brocchini, M Zloh International journal of molecular sciences 17 (6), 853, 2016 | 34 | 2016 |
| An Expanded Conformation of an Antibody Fab Region by X-Ray Scattering, Molecular Dynamics, and smFRET Identifies an Aggregation Mechanism N Codina, D Hilton, C Zhang, N Chakroun, SS Ahmad, SJ Perkins, ... Journal of molecular biology 431 (7), 1409-1425, 2019 | 29 | 2019 |
| Comparison of the pH-and thermally-induced fluctuations of a therapeutic antibody Fab fragment by molecular dynamics simulation C Zhang, N Codina, J Tang, H Yu, N Chakroun, F Kozielski, PA Dalby Computational and structural biotechnology journal 19, 2726-2741, 2021 | 12 | 2021 |
| Lyophilization to enable distribution of ChAdOx1 and ChAdOx2 adenovirus-vectored vaccines without refrigeration C Zhang, A Berg, C Joe, PA Dalby, A Douglas NPJ Vaccines, 2023 | 8 | 2023 |
| Machine learning reveals hidden stability code in protein native fluorescence H Zhang, Y Yang, C Zhang, SS Farid, PA Dalby Computational and structural biotechnology journal 19, 2750-2760, 2021 | 7 | 2021 |
| Enhanced Thermal Stability and Reduced Aggregation in an Antibody Fab Fragment at Elevated Concentrations C Zhang, JW Bye, LH Lui, H Zhang, J Hales, S Brocchini, RA Curtis, ... Molecular Pharmaceutics, 2023 | 6 | 2023 |
| Directed evolution for soluble and active periplasmic expression of bovine enterokinase in Escherichia coli W Lee, S Pradhan, C Zhang, N Venanzi, W Li, S Goldrick, PA Dalby | 4 | 2022 |
| Insights into the stability of a therapeutic antibody Fab fragment by molecular dynamics and its stabilization by computational design N Codina, C Zhang, N Chakroun, PA Dalby BioRxiv, 644369, 2019 | 4 | 2019 |
| Freeze-drying of engineered proteins using protein modelling tools and experimental validation C Zhang UCL (University College London), 2017 | 2 | 2017 |
| Crystal structures and molecular dynamics simulations of a humanised antibody fragment at acidic to basic pH J Tang, C Zhang, NC Castillo, CJ Lalaurie, X Gao, PA Dalby, F Kozielski Scientific Reports 13 (1), 16281, 2023 | 1 | 2023 |
| Assessing and Engineering Antibody Stability Using Experimental and Computational Methods C Zhang, PA Dalby Computer-Aided Antibody Design, 165-197, 2023 | 1 | 2023 |
| The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer J Tang, C Zhang, P Dalby, FG Kozielski bioRxiv, 2022 | 1 | 2022 |
| Molecular Dynamics Simulations Reveal How Competing Protein–Surface Interactions for Glycine, Citrate, and Water Modulate Stability in Antibody Fragment Formulations A Pandya, C Zhang, TS Barata, S Brocchini, MJ Howard, M Zloh, ... Molecular Pharmaceutics, 2024 | | 2024 |
| An Open Source In Silico Workflow to Assist in the Design of Fusion Proteins CJ Lalaurie, C Zhang, SM Liu, KA Bunting, PA Dalby Computational Biology and Chemistry, 108209, 2024 | | 2024 |
| An investigation into the effect of polysorbate 80 grade in biotherapeutic formulations SJ Gurgul, G Kollamaram, C Zhang, G Williams International Journal of Pharmaceutical Excipients 1 (1), 25-55, 2024 | | 2024 |
| PDB entry 7NFA F Tang, J., Zhang, C., Dalby, P., Kozielski https://www.rcsb.org/structure/7NFA, 2021 | | 2021 |
| PDB entry 7NC0 F Tang, J., Zhang, C., Dalby, P., Kozielski https://www.rcsb.org/structure/7NC0, 2021 | | 2021 |
| Elucidation of an Expanded Aggregation-Prone Conformation of Fab Using Saxs, Md Simulations and Smfret N Codina, P Dalby, S Perkins, D Hilton, C Zhang PROTEIN SCIENCE 27, 37-37, 2018 | | 2018 |
