Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma M Krauthammer, Y Kong, BH Ha, P Evans, A Bacchiocchi, JP McCusker, ... Nature genetics 44 (9), 1006-1014, 2012 | 1377 | 2012 |
RAC1P29S is a spontaneously activating cancer-associated GTPase MJ Davis, BH Ha, EC Holman, R Halaban, J Schlessinger, TJ Boggon Proceedings of the National Academy of Sciences 110 (3), 912-917, 2013 | 200 | 2013 |
Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity C Chen, BH Ha, AF Thévenin, HJ Lou, R Zhang, KY Yip, JR Peterson, ... Molecular cell 53 (1), 140-147, 2014 | 113 | 2014 |
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate BH Ha, MJ Davis, C Chen, HJ Lou, J Gao, R Zhang, M Krauthammer, ... Proceedings of the National Academy of Sciences 109 (40), 16107-16112, 2012 | 108 | 2012 |
Signaling, regulation, and specificity of the type II p21-activated kinases BH Ha, EM Morse, BE Turk, TJ Boggon Journal of Biological Chemistry 290 (21), 12975-12983, 2015 | 64 | 2015 |
Structure of ubiquitin-fold modifier 1-specific protease UfSP2 BH Ha, YJ Jeon, SC Shin, K Tatsumi, M Komatsu, K Tanaka, CM Watson, ... Journal of Biological Chemistry 286 (12), 10248-10257, 2011 | 64 | 2011 |
Structural basis for Ufm1 processing by UfSP1 BH Ha, HC Ahn, SH Kang, K Tanaka, CH Chung, EEK Kim Journal of Biological Chemistry 283 (21), 14893-14900, 2008 | 59 | 2008 |
The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization BH Ha, TJ Boggon Journal of Biological Chemistry 293 (5), 1642-1650, 2018 | 58 | 2018 |
Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation GL Gonzalez-Del Pino, K Li, E Park, AM Schmoker, BH Ha, MJ Eck Proceedings of the National Academy of Sciences 118 (36), e2107207118, 2021 | 54 | 2021 |
Crystal structures of enoyl-ACP reductases I (FabI) and III (FabL) from B. subtilis KH Kim, BH Ha, SJ Kim, SK Hong, KY Hwang, EEK Kim Journal of molecular biology 406 (3), 403-415, 2011 | 51 | 2011 |
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output CJ Miller, HJ Lou, C Simpson, B van de Kooij, BH Ha, OS Fisher, ... PLoS biology 17 (3), e2006540, 2019 | 49 | 2019 |
Structures of proteases for ubiqutin and ubiquitin-like modifiers BH Ha, EEK Kim BMB reports 41 (6), 435-443, 2008 | 41 | 2008 |
Purification and characterization of a 28-kDa major protein from ginseng root JY Yoon, BH Ha, JS Woo, YH Lim, KH Kim Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2002 | 38 | 2002 |
CDC42 binds PAK4 via an extended GTPase-effector interface BH Ha, TJ Boggon Proceedings of the National Academy of Sciences 115 (3), 531-536, 2018 | 36 | 2018 |
PAK6 targets to cell–cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape EM Morse, X Sun, JR Olberding, BH Ha, TJ Boggon, DA Calderwood Journal of cell science 129 (2), 380-393, 2016 | 30 | 2016 |
Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors KJ Choi, KM Noh, DE Kim, BH Ha, EE Kim, MY Yoon Archives of biochemistry and biophysics 466 (1), 24-30, 2007 | 27 | 2007 |
Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6 J Gao, BH Ha, HJ Lou, EM Morse, R Zhang, DA Calderwood, BE Turk, ... PLoS One 8 (10), e77818, 2013 | 26 | 2013 |
Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib E Tkacik, K Li, G Gonzalez-Del Pino, BH Ha, J Vinals, E Park, TS Beyett, ... Journal of Biological Chemistry 299 (5), 2023 | 22 | 2023 |
Structure of the ABL2/ARG kinase in complex with dasatinib BH Ha, MA Simpson, AJ Koleske, TJ Boggon Structural Biology and Crystallization Communications 71 (4), 443-448, 2015 | 20 | 2015 |
Rho family GTPase signaling through type II p21-activated kinases AK Chetty, BH Ha, TJ Boggon Cellular and Molecular Life Sciences 79 (12), 598, 2022 | 17 | 2022 |