Прати
Lukas John
Lukas John
University Hospital Heidelberg
Верификована је имејл адреса на med.uni-heidelberg.de
Наслов
Навело
Навело
Година
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics
SM Tirier, JP Mallm, S Steiger, AM Poos, MHS Awwad, N Giesen, ...
Nature Communications 12 (1), 6960, 2021
1052021
Pathway-directed therapy in multiple myeloma
L John, MT Krauth, K Podar, MS Raab
Cancers 13 (7), 1668, 2021
442021
Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
C Schinke, AM Poos, M Bauer, L John, S Johnson, S Deshpande, ...
Blood Advances 6 (22), 5873-5883, 2022
342022
Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis
AM Poos, N Prokoph, MJ Przybilla, JP Mallm, S Steiger, I Seufert, L John, ...
Blood 142 (19), 1633-1646, 2023
302023
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level
L John, AM Poos, A Brobeil, C Schinke, S Huhn, N Prokoph, R Lutz, ...
Nature Communications 14 (1), 5011, 2023
212023
Application of an artificial intelligence-based tool in [18F]FDG PET/CT for the assessment of bone marrow involvement in multiple myeloma
C Sachpekidis, O Enqvist, J Ulén, A Kopp-Schneider, L Pan, A Jauch, ...
European Journal of Nuclear Medicine and Molecular Imaging 50 (12), 3697-3708, 2023
162023
The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma
AM Cirrincione, AM Poos, B Ziccheddu, M Kaddoura, MA Baertsch, ...
Blood Journal, blood. 2024024299, 2024
82024
Comprehensive comparison of early relapse and end-stage relapsed refractory multiple myeloma
AM Poos, N Giesen, C Catalano, N Paramasivam, D Huebschmann, ...
Blood 136, 1, 2020
72020
Idecabtagene Vicleucel Is Well Tolerated and Effective in Relapsed/Refractory Myeloma Patients with Prior Allogeneic Stem Cell Transplantation
L John, S Sauer, U Hegenbart, P Dreger, M Hundemer, C Müller-Tidow, ...
Transplantation and Cellular Therapy 29 (10), 609. e1-609. e6, 2023
52023
Daratumumab and antineoplastic therapy versus antineoplastic therapy only for adults with newly diagnosed multiple myeloma ineligible for transplant
P Langer, L John, I Monsef, C Scheid, V Piechotta, N Skoetz
Cochrane Database of Systematic Reviews, 2024
42024
Bone marrow immune signatures in multiple myeloma are linked to tumor heterogeneity and treatment outcome
S Steiger, R Lutz, N Prokoph, S Palit, SM Tirier, P Reichert, A Baumann, ...
Blood 140 (Supplement 1), 2083-2085, 2022
42022
Midkine promotes metastasis and therapeutic resistance via mTOR/RPS6 in uveal melanoma
MM Karg, L John, N Refaian, C Buettner, T Rottmar, J Sommer, B Bock, ...
Molecular Cancer Research 20 (8), 1320-1336, 2022
32022
The spatial heterogeneity in newly diagnosed multiple myeloma patients-from sub-clonal architecture to the immune microenvironment
L John, A Poos, SM Tirier, JP Mallm, N Prokoph, A Brobeil, R Lutz, ...
Blood 138, 729, 2021
32021
Efficacy and safety of daratumumab for the treatment of multiple myeloma: a series of Cochrane reviews
C Hirsch, V Piechotta, P Langer, C Scheid, L John, N Skoetz
Hematological Oncology 39, 2021
32021
A Comprehensive Analysis of Single-Cell Chromatin Accessibility and Gene Expression Identifies Intra-Tumor Heterogeneity and Molecular Treatment Responses in Relapsed …
AM Poos, JP Mallm, SM Tirier, N Casiraghi, H Susak, N Giesen, K Bauer, ...
Blood 134, 575, 2019
32019
Clinical and serological characterization of acute pleuropericarditis suggests an autoinflammatory pathogenesis and highlights risk factors for recurrent attacks
D Kaudewitz, L John, J Meis, N Frey, HM Lorenz, F Leuschner, N Blank
Clinical Research in Cardiology, 1-9, 2024
22024
Impact of novel agent therapies on immune cell subsets and infectious complications in patients with relapsed/refractory multiple myeloma
L John, K Miah, A Benner, EK Mai, K Kriegsmann, M Hundemer, ...
Frontiers in Oncology 13, 1078725, 2023
22023
Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma
AL Grab, PS Kim, L John, K Bisht, H Wang, A Baumann, H Van de Velde, ...
Cells 13 (10), 879, 2024
12024
Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma
F Maura, MA Kaddoura, A Poos, L Baughn, B Ziccheddu, MA Bartsch, ...
bioRxiv, 2024.08. 30.610457, 2024
12024
OA-23 Resolving therapy resistance mechanisms in multiple myeloma by multi-omics subclone analysis
A Poos, N Prokoph, M Przybilla, JP Mallm, S Steiger, I Seufert, L John, ...
Clinical Lymphoma Myeloma and Leukemia 23, S14-S15, 2023
12023
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