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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling MA Daniels, E Teixeiro, J Gill, B Hausmann, D Roubaty, K Holmberg, ... Nature 444 (7120), 724-729, 2006 | 722 | 2006 |
Somatic recombination in a murine T-cell receptor gene Y Chien, NRJ Gascoigne, J Kavaler, NE Lee, MM Davis Nature 309 (5966), 322-326, 1984 | 595 | 1984 |
Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes NRJ Gascoigne, Y Chien, DM Becker, J Kavaler, MM Davis Nature 310 (5976), 387-391, 1984 | 474 | 1984 |
Photobleaching-corrected FRET efficiency imaging of live cells T Zal, NRJ Gascoigne Biophysical journal 86 (6), 3923-3939, 2004 | 470 | 2004 |
Hijacking and exploitation of IL-10 by intracellular pathogens S Redpath, P Ghazal, NRJ Gascoigne Trends in microbiology 9 (2), 86-92, 2001 | 405 | 2001 |
The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model C Rosette, G Werlen, MA Daniels, PO Holman, SM Alam, PJ Travers, ... Immunity 15 (1), 59-70, 2001 | 307 | 2001 |
Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands SM Alam, GM Davies, CM Lin, T Zal, W Nasholds, SC Jameson, ... Immunity 10 (2), 227-237, 1999 | 287 | 1999 |
Murine cytomegalovirus infection down-regulates MHC class II expression on macrophages by induction of IL-10 S Redpath, A Angulo, NRJ Gascoigne, P Ghazal The Journal of Immunology 162 (11), 6701-6707, 1999 | 216 | 1999 |
Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection T Nabekura, M Kanaya, A Shibuya, G Fu, NRJ Gascoigne, LL Lanier Immunity 40 (2), 225-234, 2014 | 210 | 2014 |
TCR signal strength and T cell development NRJ Gascoigne, V Rybakin, O Acuto, J Brzostek Annual review of cell and developmental biology 32 (1), 327-348, 2016 | 197 | 2016 |
Control of MHC restriction by TCR Vα CDR1 and CDR2 BC Sim, L Zerva, MI Greene, NRJ Gascoigne Science 273 (5277), 963-966, 1996 | 197 | 1996 |
CD28 plays a critical role in the segregation of PKCθ within the immunologic synapse J Huang, PF Lo, T Żal, NRJ Gascoigne, BA Smith, SD Levin, HM Grey Proceedings of the National Academy of Sciences 99 (14), 9369-9373, 2002 | 193 | 2002 |
Altered peptide ligands induce delayed CD8-T cell receptor interaction—a role for CD8 in distinguishing antigen quality PP Yachi, J Ampudia, T Zal, NRJ Gascoigne Immunity 25 (2), 203-211, 2006 | 191 | 2006 |
TCR affinity and negative regulation limit autoimmunity MA Gronski, JM Boulter, D Moskophidis, LT Nguyen, K Holmberg, ... Nature medicine 10 (11), 1234-1239, 2004 | 184 | 2004 |
Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy. M Dohlsten, L Abrahmsén, P Björk, PA Lando, G Hedlund, G Forsberg, ... Proceedings of the National Academy of Sciences 91 (19), 8945-8949, 1994 | 178 | 1994 |
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Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling G Fu, S Vallée, V Rybakin, MV McGuire, J Ampudia, C Brockmeyer, ... Nature immunology 10 (8), 848-856, 2009 | 172 | 2009 |
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