Distinct fibroblast subsets drive inflammation and damage in arthritis AP Croft, J Campos, K Jansen, JD Turner, J Marshall, M Attar, L Savary, ... Nature 570 (7760), 246-251, 2019 | 788 | 2019 |
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases I Korsunsky, K Wei, M Pohin, EY Kim, F Barone, T Major, E Taylor, ... Med 3 (7), 481-518. e14, 2022 | 159 | 2022 |
Critical role of synovial tissue–resident macrophage and fibroblast subsets in the persistence of joint inflammation S Kemble, AP Croft Frontiers in immunology 12, 715894, 2021 | 98 | 2021 |
Human bone marrow organoids for disease modeling, discovery, and validation of therapeutic targets in hematologic malignancies AO Khan, A Rodriguez-Romera, JS Reyat, AA Olijnik, M Colombo, ... Cancer discovery 13 (2), 364-385, 2023 | 91 | 2023 |
Identification of a transitional fibroblast function in very early rheumatoid arthritis A Filer, LSC Ward, S Kemble, CS Davies, H Munir, R Rogers, K Raza, ... Annals of the rheumatic diseases 76 (12), 2105-2112, 2017 | 81 | 2017 |
Adipogenic differentiation of mesenchymal stem cells alters their immunomodulatory properties in a tissue-specific manner H Munir, LSC Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, ... Stem cells 35 (6), 1636-1646, 2017 | 66 | 2017 |
Fibroblast pathology in inflammatory joint disease LJ Marsh, S Kemble, P Reis Nisa, R Singh, AP Croft Immunological reviews 302 (1), 163-183, 2021 | 46 | 2021 |
Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry S Kemble, A Dalby, GC Lowe, PLR Nicolson, SP Watson, Y Senis, ... Blood advances 6 (9), 2932-2946, 2022 | 20 | 2022 |
CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis S Rauber, H Mohammadian, C Schmidkonz, A Atzinger, A Soare, ... Nature Immunology 25 (4), 682-692, 2024 | 18 | 2024 |
Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss JW Lewis, K Frost, G Neag, M Wahid, M Finlay, EH Northall, O Abudu, ... Cell Reports Medicine 5 (5), 2024 | 15 | 2024 |
Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis S Ahmed, CB Mahony, A Torres, J Murillo-Saich, S Kemble, M Cedeno, ... Arthritis Research & Therapy 25 (1), 176, 2023 | 9 | 2023 |
O014 Podoplanin (GP38), a marker of synovial inflammation, is an excellent therapeutic target in mouse collagen-induced arthritis GE Desanti, AN Saghir, AJ Naylor, S Kemble, J Falconer, C Wehmeyer, ... Annals of the Rheumatic Diseases 77, A7-A8, 2018 | 8 | 2018 |
Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues JS Reyat, A di Maio, B Grygielska, J Pike, S Kemble, ... Frontiers in cardiovascular medicine 10, 1156759, 2023 | 6 | 2023 |
Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes A Torres, S Kang, CB Mahony, M Cedeño, PG Oliveira, ... Frontiers in immunology 14, 1103231, 2023 | 6 | 2023 |
Platelet counting S Kemble, C Briggs, P Harrison Platelets, 581-591, 2019 | 6 | 2019 |
O013 New therapeutic avenues in rheumatoid arthritis: exploring the role of the adiponectin-pepitem axis S Kemble, LE Harford, HM McGettrick Annals of the Rheumatic Diseases 77, A7, 2018 | 4 | 2018 |
Bench to Bedside: Modelling Inflammatory Arthritis CI Chidomere, M Wahid, S Kemble, C Chadwick, R Thomas, RS Hardy, ... Discovery Immunology 2 (1), kyac010, 2023 | 3 | 2023 |
Comprehensive functional characterization of a novel ANO6 variant in a new patient with Scott syndrome SJ Montague, J Price, K Pennycott, NJ Pavey, EM Martin, I Thirlwell, ... Journal of Thrombosis and Haemostasis 22 (8), 2281-2293, 2024 | 2 | 2024 |
Human bone marrow organoids enable the study of hematopoietic cell-stromal interactions and support the survival of malignant cells from patients A Khan, A Rodriguez-Romera, M Colombo, JS Reyat, G Wang, WX Wen, ... Blood 140 (Supplement 1), 1679-1681, 2022 | 2 | 2022 |
02.07 Prophylactic treatment with pepitem inhibits onset of collagen induced arthritis and pepitem therapy reduces disease severity S Kemble, AP Croft, G Desanti, A Saghir, CD Buckley, HM McGettrick Annals of the Rheumatic Diseases 76, A10-A11, 2017 | 2 | 2017 |