Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1980 | 2019 |
Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci M Lemire, SHE Zaidi, M Ban, B Ge, D Aïssi, M Germain, I Kassam, ... Nature communications 6 (1), 6326, 2015 | 154 | 2015 |
Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease CL Vallerga, F Zhang, J Fowdar, AF McRae, T Qi, MF Nabais, Q Zhang, ... Nature communications 11 (1), 1238, 2020 | 133 | 2020 |
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability RH Reynolds, J Botía, MA Nalls, J Hardy, SA Gagliano Taliun, M Ryten npj Parkinson's Disease 5 (1), 6, 2019 | 100 | 2019 |
The effect of X-linked dosage compensation on complex trait variation J Sidorenko, I Kassam, KE Kemper, J Zeng, LR Lloyd-Jones, ... Nature communications 10 (1), 3009, 2019 | 65 | 2019 |
Genetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson’s disease H Leonard, C Blauwendraat, L Krohn, F Faghri, H Iwaki, G Ferguson, ... Journal of medical genetics 57 (5), 331-338, 2020 | 61 | 2020 |
Tissue-specific sex differences in human gene expression I Kassam, Y Wu, J Yang, PM Visscher, AF McRae Human molecular genetics 28 (17), 2976-2986, 2019 | 58 | 2019 |
Association of the APOE-ε4 allele with outcome of traumatic brain injury in children and youth: a meta-analysis and meta-regression I Kassam, F Gagnon, MD Cusimano Journal of Neurology, Neurosurgery & Psychiatry 87 (4), 433-440, 2016 | 56 | 2016 |
Blood triglyceride levels are associated with DNA methylation at the serine metabolism gene PHGDH V Truong, S Huang, J Dennis, M Lemire, N Zwingerman, D Aïssi, ... Scientific reports 7 (1), 11207, 2017 | 45 | 2017 |
Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals Y Chen, I Kassam, SH Lau, JS Kooner, R Wilson, A Peters, J Winkelmann, ... Clinical Epigenetics 13, 1-13, 2021 | 30 | 2021 |
Integrative profiling of T790M-negative EGFR-mutated NSCLC reveals pervasive lineage transition and therapeutic opportunities KP Chua, YHF Teng, AC Tan, A Takano, JJS Alvarez, R Nahar, N Rohatgi, ... Clin Cancer Res 27 (21), 5939-5950, 2021 | 29 | 2021 |
Autosomal genetic control of human gene expression does not differ across the sexes I Kassam, L Lloyd-Jones, A Holloway, KS Small, B Zeng, A Bakshi, ... Genome biology 17 (1), 1-10, 2016 | 18 | 2016 |
New Polygenic Risk Score to Predict High Myopia in Singapore Chinese Children C Lanca, I Kassam, K Patasova, LL Foo, J Li, M Ang, QV Hoang, YY Teo, ... Translational vision science & technology 10 (8), 26-26, 2021 | 16 | 2021 |
Genetic determinants of tissue factor pathway inhibitor plasma levels J Dennis, I Kassam, PE Morange, DA Tregouet, F Gagnon Thrombosis and haemostasis 114 (08), 245-257, 2015 | 15 | 2015 |
The Potential of Current Polygenic Risk Scores to Predict High Myopia and Myopic Macular Degeneration in Multiethnic Singapore Adults I Kassam, LL Foo, C Lanca, LQ Xu, QV Hoang, CY Cheng, P Hysi, ... Ophthalmology 129 (8), 890-902, 2022 | 14 | 2022 |
Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis N Zwingerman, A Medina-Rivera, I Kassam, MD Wilson, PE Morange, ... PloS one 12 (5), e0177768, 2017 | 11 | 2017 |
Genome-wide identification of cis DNA methylation quantitative trait loci in three Southeast Asian Populations I Kassam, S Tan, FF Gan, WY Saw, LWL Tan, DKN Moong, R Soong, ... Human Molecular Genetics 30 (7), 603-618, 2021 | 9 | 2021 |
Evidence for mitochondrial genetic control of autosomal gene expression I Kassam, T Qi, L Lloyd-Jones, A Holloway, M Jan Bonder, AK Henders, ... Human molecular genetics 25 (24), 5332-5338, 2016 | 8 | 2016 |
The autosomal genetic control of sexually dimorphic traits in humans is largely the same across the sexes I Kassam, AF McRae Genome biology 17 (1), 1-3, 2016 | 7 | 2016 |
Main existing datasets for open data research on humans B Couvy-Duchesne, S Bottani, E Camenen, F Fang, M Fikere, ... | 2 | 2022 |