Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons K Castillo, M Nassif, V Valenzuela, F Rojas, S Matus, G Mercado, ... Autophagy 9 (9), 1308-1320, 2013 | 380 | 2013 |
Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal B van Zundert, A Yoshii, M Constantine-Paton Trends in neurosciences 27 (7), 428-437, 2004 | 326 | 2004 |
Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis B van Zundert, MH Peuscher, M Hynynen, A Chen, RL Neve, RH Brown Jr, ... The Journal of Neuroscience 28 (43), 10864-10874, 2008 | 276 | 2008 |
Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice FJ Bustos, E Ampuero, N Jury, R Aguilar, F Falahi, J Toledo, J Ahumada, ... Brain 140 (12), 3252-3268, 2017 | 175 | 2017 |
Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress F Rojas, N Cortes, S Abarzua, A Dyrda, B van Zundert Frontiers in cellular neuroscience 8, 24, 2014 | 140 | 2014 |
Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability E Fritz, P Izaurieta, A Weiss, FR Mir, P Rojas, D Gonzalez, F Rojas, ... Journal of neurophysiology 109 (11), 2803-2814, 2013 | 136 | 2013 |
ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers D Gonzalez, O Contreras, DL Rebolledo, JP Espinoza, B Van Zundert, ... PloS one 12 (5), e0177649, 2017 | 134 | 2017 |
ALS‐linked protein disulfide isomerase variants cause motor dysfunction U Woehlbier, A Colombo, MJ Saaranen, V Pérez, J Ojeda, FJ Bustos, ... The EMBO journal 35 (8), 845-865, 2016 | 129 | 2016 |
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling F Rojas, D Gonzalez, N Cortes, E Ampuero, DE Hernández, E Fritz, ... Frontiers in cellular neuroscience 9, 203, 2015 | 105 | 2015 |
Early pathogenesis in the adult‐onset neurodegenerative disease amyotrophic lateral sclerosis B Van Zundert, P Izaurieta, E Fritz, FJ Alvarez Journal of cellular biochemistry 113 (11), 3301-3312, 2012 | 100 | 2012 |
Dissecting the role of redox signaling in neuronal development DA Bórquez, PJ Urrutia, C Wilson, B Van Zundert, MT Núñez, ... Journal of neurochemistry 137 (4), 506-517, 2016 | 96 | 2016 |
Differential roles of NMDA receptor subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1 FJ Sepulveda, FJ Bustos, E Inostroza, FA Zúñiga, RL Neve, M Montecino, ... Journal of neurophysiology 103 (4), 1758-1770, 2010 | 96 | 2010 |
Epigenetic control of the bone-master Runx2 gene during osteoblast-lineage commitment by the histone demethylase JARID1B/KDM5B A Rojas, R Aguilar, B Henriquez, JB Lian, JL Stein, GS Stein, ... Journal of biological chemistry 290 (47), 28329-28342, 2015 | 95 | 2015 |
Pathogenicity of Lupus Anti–Ribosomal P Antibodies: Role of Cross‐Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model F Segovia‐Miranda, F Serrano, A Dyrda, E Ampuero, C Retamal, ... Arthritis & rheumatology 67 (6), 1598-1610, 2015 | 92 | 2015 |
Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution L Calderón-Garcidueñas, A Herrera-Soto, N Jury, BA Maher, ... Environmental research 183, 109226, 2020 | 90 | 2020 |
PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors FJ Bustos, L Varela-Nallar, M Campos, B Henriquez, M Phillips, C Opazo, ... PLoS One 9 (4), e94037, 2014 | 90 | 2014 |
Silencing strategies for therapy of SOD1-mediated ALS B van Zundert, RH Brown Jr Neuroscience Letters 636, 32-39, 2017 | 89 | 2017 |
Changes on the properties of glycine receptors during neuronal development LG Aguayo, B Van Zundert, JC Tapia, MA Carrasco, FJ Alvarez Brain research reviews 47 (1-3), 33-45, 2004 | 86 | 2004 |
Alterations in the motor neuron–renshaw cell circuit in the Sod1G93A mouse model H Wootz, E FitzSimons‐Kantamneni, M Larhammar, TM Rotterman, ... Journal of Comparative Neurology 521 (7), 1449-1469, 2013 | 85 | 2013 |
Interactive and additive influences of Gender, BMI and Apolipoprotein 4 on cognition in children chronically exposed to high concentrations of PM2. 5 and ozone. APOE 4 females … L Calderón-Garcidueñas, V Jewells, C Galaz-Montoya, B van Zundert, ... Environmental research 150, 411-422, 2016 | 84 | 2016 |