Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo E Martinez, VB Palhan, A Tjernberg, ES Lymar, AM Gamper, TK Kundu, ... Molecular and cellular biology 21 (20), 6782-6795, 2001 | 499 | 2001 |
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration VB Palhan, S Chen, GH Peng, A Tjernberg, AM Gamper, Y Fan, BT Chait, ... Proceedings of the National Academy of Sciences 102 (24), 8472-8477, 2005 | 280 | 2005 |
Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis D Hu, M Gur, Z Zhou, A Gamper, MC Hung, N Fujita, L Lan, I Bahar, ... Nature communications 6 (1), 1-15, 2015 | 148 | 2015 |
Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis AB Bukhari, CW Lewis, JJ Pearce, D Luong, GK Chan, AM Gamper The Journal of clinical investigation 129 (3), 1329-1344, 2019 | 141 | 2019 |
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity X Qiao, L Zhang, AM Gamper, T Fujita, Y Wan Cell cycle 9 (19), 3904-3912, 2010 | 121 | 2010 |
Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage AM Gamper, RG Roeder Molecular and cellular biology 28 (8), 2517-2527, 2008 | 87 | 2008 |
Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis AM Gamper, X Qiao, J Kim, L Zhang, MC DeSimone, WK Rathmell, Y Wan Molecular cell 45 (2), 233-243, 2012 | 85 | 2012 |
ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage AM Gamper, R Rofougaran, SC Watkins, JS Greenberger, JH Beumer, ... Nucleic acids research 41 (22), 10334-10344, 2013 | 84 | 2013 |
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis AM Gamper, J Kim, RG Roeder Molecular and cellular biology 29 (1), 266-280, 2009 | 80 | 2009 |
Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen HJ Kwun, M Shuda, CJ Camacho, AM Gamper, M Thant, Y Chang, ... Journal of virology 89 (8), 4191-4200, 2015 | 79 | 2015 |
Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors S Choi, AM Gamper, JS White, CJ Bakkenist Cell cycle 9 (20), 4052-4057, 2010 | 72 | 2010 |
Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition CW Lewis, AB Bukhari, EJ Xiao, WS Choi, JD Smith, E Homola, ... Cancer research 79 (23), 5971-5985, 2019 | 59 | 2019 |
Targeting the DNA damage response for cancer therapy by inhibiting the kinase Wee1 AB Bukhari, GK Chan, AM Gamper Frontiers in Oncology 12, 828684, 2022 | 39 | 2022 |
ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis AM Gamper, S Choi, Y Matsumoto, D Banerjee, AE Tomkinson, ... Journal of Biological Chemistry 287 (15), 12445-12454, 2012 | 28 | 2012 |
Comparative molecular field analysis of haptens docked to the multispecific antibody IgE (Lb4) AM Gamper, RH Winger, KR Liedl, CA Sotriffer, JM Varga, RT Kroemer, ... Journal of medicinal chemistry 39 (20), 3882-3888, 1996 | 21 | 1996 |
Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19 TN Moiseeva, AM Gamper, BL Hood, TP Conrads, CJ Bakkenist DNA repair 43, 9-17, 2016 | 10 | 2016 |
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma J Zhou, YS Kong, KM Vincent, D Dieters‐Castator, AB Bukhari, ... Molecular Oncology 17 (9), 1763-1783, 2023 | 9 | 2023 |
Docosahexaenoic acid in the inhibition of tumor cell growth in preclinical models of ovarian cancer O Bilyk, B Hamedi, I Dutta, M Newell, AB Bukhari, AM Gamper, RC McVea, ... Nutrition and Cancer 74 (4), 1431-1445, 2022 | 9 | 2022 |
Heteroligation of a mouse monoclonal IgE antibody (La2) with small molecules, analysed by computer-aided automated docking CA Sotriffer, KR Liedl, RH Winger, AM Gamper, RT Kroemer, ... Molecular immunology 33 (2), 129-144, 1996 | 9 | 1996 |
Radiation combined with oncolytic vaccinia virus provides pronounced antitumor efficacy and induces immune protection in an aggressive glioblastoma model QT Storozynsky, KC Agopsowicz, RS Noyce, AB Bukhari, X Han, ... Cancer Letters 562, 216169, 2023 | 8 | 2023 |