| Crystal structure of the µ-opioid receptor bound to a morphinan antagonist A Manglik, AC Kruse, TS Kobilka, FS Thian, JM Mathiesen, RK Sunahara, ... Nature 485 (7398), 321-326, 2012 | 1637 | 2012 |
| Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor MP Bokoch, Y Zou, SGF Rasmussen, CW Liu, R Nygaard, ... Nature 463 (7277), 108-112, 2010 | 585 | 2010 |
| A molecular dissection of the glycoprotein hormone receptors G Vassart, L Pardo, S Costagliola Trends in biochemical sciences 29 (3), 119-126, 2004 | 411 | 2004 |
| Glycoprotein hormone receptors: determinants in leucine‐rich repeats responsible for ligand specificity G Smits, M Campillo, C Govaerts, V Janssens, C Richter, G Vassart, ... The EMBO journal, 2003 | 238 | 2003 |
| Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors X Viñals, E Moreno, L Lanfumey, A Cordomí, A Pastor, R de La Torre, ... PLoS biology 13 (7), e1002194, 2015 | 229 | 2015 |
| Ligand‐regulated oligomerization of β2‐adrenoceptors in a model lipid bilayer JJ Fung, X Deupi, L Pardo, XJ Yao, GA Velez‐Ruiz, BT DeVree, ... The EMBO journal 28 (21), 3315-3328, 2009 | 226 | 2009 |
| Pharmacogenomic and structural analysis of constitutive G protein–coupled receptor activity MJ Smit, HF Vischer, RA Bakker, A Jongejan, H Timmerman, L Pardo, ... Annu. Rev. Pharmacol. Toxicol. 47 (1), 53-87, 2007 | 220 | 2007 |
| Serine and threonine residues bend α-helices in the χ1= g− conformation JA Ballesteros, X Deupi, M Olivella, EEJ Haaksma, L Pardo Biophysical journal 79 (5), 2754-2760, 2000 | 212 | 2000 |
| Serotonin 5-HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease B Benhamú, M Martín-Fontecha, H Vázquez-Villa, L Pardo, ... Journal of medicinal chemistry 57 (17), 7160-7181, 2014 | 175 | 2014 |
| Membrane protein simulations using AMBER force field and Berger lipid parameters A Cordomi, G Caltabiano, L Pardo Journal of chemical theory and computation 8 (3), 948-958, 2012 | 170 | 2012 |
| The TXP motif in the second transmembrane helix of CCR5: a structural determinant of chemokine-induced activation C Govaerts, C Blanpain, X Deupi, S Ballet, JA Ballesteros, SJ Wodak, ... Journal of Biological Chemistry 276 (16), 13217-13225, 2001 | 169 | 2001 |
| Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line E Pérez-Sacau, RG Díaz-Peñate, A Estévez-Braun, AG Ravelo, ... Journal of medicinal chemistry 50 (4), 696-706, 2007 | 167 | 2007 |
| The role of internal water molecules in the structure and function of the rhodopsin family of G protein‐coupled receptors L Pardo, X Deupi, N Dölker, ML López‐Rodríguez, M Campillo ChemBioChem 8 (1), 19-24, 2007 | 144 | 2007 |
| Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers G Navarro, S Ferré, A Cordomi, E Moreno, J Mallol, V Casadó, A Cortés, ... Journal of Biological Chemistry 285 (35), 27346-27359, 2010 | 136 | 2010 |
| An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor E Urizar, S Claeysen, X Deupí, C Govaerts, S Costagliola, G Vassart, ... Journal of Biological Chemistry 280 (17), 17135-17141, 2005 | 136 | 2005 |
| Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs G Navarro, A Cordomí, M Zelman-Femiak, M Brugarolas, E Moreno, ... BMC biology 14, 1-12, 2016 | 135 | 2016 |
| Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase G Navarro, A Cordomí, V Casadó-Anguera, E Moreno, NS Cai, A Cortés, ... Nature communications 9 (1), 1242, 2018 | 130 | 2018 |
| A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor C Govaerts, A Lefort, S Costagliola, SJ Wodak, JA Ballesteros, ... Journal of Biological Chemistry 276 (25), 22991-22999, 2001 | 130 | 2001 |
| On the use of the transmembrane domain of bacteriorhodopsin as a template for modeling the three-dimensional structure of guanine nucleotide-binding regulatory protein-coupled … L Pardo, JA Ballesteros, R Osman, H Weinstein Proceedings of the National Academy of Sciences 89 (9), 4009-4012, 1992 | 127 | 1992 |
| A Three-Dimensional Pharmacophore Model for 5-Hydroxytryptamine6 (5-HT6) Receptor Antagonists ML López-Rodríguez, B Benhamú, T De La Fuente, A Sanz, L Pardo, ... Journal of medicinal chemistry 48 (13), 4216-4219, 2005 | 124 | 2005 |
