A predictive computational framework for direct reprogramming between human cell types OJL Rackham, J Firas, H Fang, ME Oates, ML Holmes, AS Knaupp, ... Nature genetics 48 (3), 331-335, 2016 | 320 | 2016 |
Reprogramming roadmap reveals route to human induced trophoblast stem cells X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ... Nature 586 (7827), 101-107, 2020 | 186 | 2020 |
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ... Nature Methods 14 (11), 1055-1062, 2017 | 170 | 2017 |
Transient and permanent reconfiguration of chromatin and transcription factor occupancy drive reprogramming AS Knaupp, S Buckberry, J Pflueger, SM Lim, E Ford, MR Larcombe, ... Cell stem cell 21 (6), 834-845. e6, 2017 | 127 | 2017 |
In vitro differentiation of human cord blood-derived unrestricted somatic stem cells towards an endodermal pathway S Sensken, S Waclawczyk, AS Knaupp, T Trapp, J Enczmann, P Wernet, ... Cytotherapy 9 (4), 362-378, 2007 | 65 | 2007 |
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program M Ratnadiwakara, SK Archer, CI Dent, I Ruiz De Los Mozos, TH Beilharz, ... Elife 7, e37419, 2018 | 61 | 2018 |
Cell type of origin dictates the route to pluripotency CM Nefzger, FJ Rossello, J Chen, X Liu, AS Knaupp, J Firas, JM Paynter, ... Cell reports 21 (10), 2649-2660, 2017 | 58 | 2017 |
Temporal changes in fibrinolysis following injury HB Moore, EE Moore Seminars in thrombosis and hemostasis 46 (02), 189-198, 2020 | 56 | 2020 |
Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin AL Samson, AS Knaupp, M Sashindranath, RJ Borg, AEL Au, EJ Cops, ... Cell Reports 2 (4), 889-901, 2012 | 54 | 2012 |
Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase AL Samson, AS Knaupp, I Kass, O Kleifeld, EM Marijanovic, VA Hughes, ... Journal of Biological Chemistry 289 (39), 26922-26936, 2014 | 52 | 2014 |
Kinetic instability of the serpin Z α1-antitrypsin promotes aggregation AS Knaupp, V Levina, AL Robertson, MC Pearce, SP Bottomley Journal of molecular biology 396 (2), 375-383, 2010 | 51 | 2010 |
A versatile strategy for isolating a highly enriched population of intestinal stem cells CM Nefzger, T Jardé, FJ Rossello, K Horvay, AS Knaupp, DR Powell, ... Stem Cell Reports 6 (3), 321-329, 2016 | 40 | 2016 |
Serpin polymerization and its role in disease—The molecular basis of α1‐antitrypsin deficiency AS Knaupp, SP Bottomley Iubmb Life 61 (1), 1-5, 2009 | 36 | 2009 |
Conformational properties of the disease-causing Z variant of α1-antitrypsin revealed by theory and experiment I Kass, AS Knaupp, SP Bottomley, AM Buckle Biophysical journal 102 (12), 2856-2865, 2012 | 30 | 2012 |
Expression, purification and characterization of recombinant Z α1-antitrypsin—the most common cause of α1-antitrypsin deficiency V Levina, W Dai, AS Knaupp, D Kaiserman, MC Pearce, LD Cabrita, ... Protein expression and purification 68 (2), 226-232, 2009 | 28 | 2009 |
3D-cardiomics: A spatial transcriptional atlas of the mammalian heart M Mohenska, NM Tan, A Tokolyi, MB Furtado, MW Costa, AJ Perry, ... Journal of molecular and cellular cardiology 163, 20-32, 2022 | 23 | 2022 |
Cell surface marker mediated purification of iPS cell intermediates from a reprogrammable mouse model CM Nefzger, S Alaei, AS Knaupp, ML Holmes, JM Polo Journal of Visualized Experiments: Jove, 51728, 2014 | 23 | 2014 |
Structural change in β-sheet A of Z α1-antitrypsin is responsible for accelerated polymerization and disease AS Knaupp, SP Bottomley Journal of molecular biology 413 (4), 888-898, 2011 | 20 | 2011 |
Fibrinolysis and the immune response in trauma RL Medcalf, CB Keragala, DF Draxler Seminars in thrombosis and hemostasis 46 (02), 176-182, 2020 | 19 | 2020 |
The Roles of Helix I and Strand 5A in the Folding, Function and Misfolding of α1-Antitrypsin AS Knaupp, S Keleher, L Yang, W Dai, SP Bottomley, MC Pearce PLoS One 8 (1), e54766, 2013 | 19 | 2013 |