The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b MP Müller, H Peters, J Blümer, W Blankenfeldt, RS Goody, A Itzen Science 329 (5994), 946-949, 2010 | 450 | 2010 |
RabGEFs are a major determinant for specific Rab membrane targeting J Blümer, J Rey, L Dehmelt, T Mazel, YW Wu, P Bastiaens, RS Goody, ... Journal of Cell Biology 200 (3), 287-300, 2013 | 237 | 2013 |
Rab GTPase–Myo5B complexes control membrane recycling and epithelial polarization JT Roland, DM Bryant, A Datta, A Itzen, KE Mostov, JR Goldenring Proceedings of the National Academy of Sciences 108 (7), 2789-2794, 2011 | 230 | 2011 |
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity S Schoebel, LK Oesterlin, W Blankenfeldt, RS Goody, A Itzen Molecular cell 36 (6), 1060-1072, 2009 | 205 | 2009 |
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1 YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ... The EMBO journal 34 (22), 2840-2861, 2015 | 193 | 2015 |
Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins PR Goody, K Heller, LK Oesterlin, MP Müller, A Itzen, RS Goody The EMBO journal 31 (7), 1774-1784, 2012 | 138 | 2012 |
Nucleotide exchange via local protein unfolding—structure of Rab8 in complex with MSS4 A Itzen, O Pylypenko, RS Goody, K Alexandrov, A Rak The EMBO journal 25 (7), 1445-1455, 2006 | 127 | 2006 |
GTPases involved in vesicular trafficking: structures and mechanisms A Itzen, RS Goody Seminars in cell & developmental biology 22 (1), 48-56, 2011 | 123 | 2011 |
Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection E Rothmeier, G Pfaffinger, C Hoffmann, CF Harrison, H Grabmayr, ... PLoS pathogens 9 (9), e1003598, 2013 | 122 | 2013 |
A structural basis for Lowe syndrome caused by mutations in the Rab‐binding domain of OCRL1 X Hou, N Hagemann, S Schoebel, W Blankenfeldt, RS Goody, ... The EMBO journal 30 (8), 1659-1670, 2011 | 118 | 2011 |
High‐affinity binding of phosphatidylinositol 4‐phosphate by Legionella pneumophila DrrA S Schoebel, W Blankenfeldt, RS Goody, A Itzen EMBO reports 11 (8), 598-604, 2010 | 110 | 2010 |
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner G Yin, TL Da Fonseca, SE Eisbach, AM Anduaga, C Breda, ML Orcellet, ... Neurobiology of disease 70, 149-161, 2014 | 106 | 2014 |
Direct Targeting of Rab‐GTPase–Effector Interactions J Spiegel, PM Cromm, A Itzen, RS Goody, TN Grossmann, H Waldmann Angewandte Chemie International Edition 53 (9), 2498-2503, 2014 | 106 | 2014 |
The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting F Li, L Yi, L Zhao, A Itzen, RS Goody, YW Wu Proceedings of the National Academy of Sciences 111 (7), 2572-2577, 2014 | 103 | 2014 |
Protein LidA from Legionella is a rab GTPase supereffector S Schoebel, AL Cichy, RS Goody, A Itzen Proceedings of the National Academy of Sciences 108 (44), 17945-17950, 2011 | 91 | 2011 |
Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor LK Oesterlin, RS Goody, A Itzen Proceedings of the National Academy of Sciences 109 (15), 5621-5626, 2012 | 81 | 2012 |
Proximity‐triggered covalent stabilization of low‐affinity protein complexes in vitro and in vivo M Cigler, TG Müller, D Horn‐Ghetko, MK von Wrisberg, M Fottner, ... Angewandte Chemie international edition 56 (49), 15737-15741, 2017 | 79 | 2017 |
Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation L Langemeyer, R Nunes Bastos, Y Cai, A Itzen, KM Reinisch, FA Barr Elife 3, e01623, 2014 | 79 | 2014 |
Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB E Mihai Gazdag, A Streller, I Haneburger, H Hilbi, IR Vetter, RS Goody, ... EMBO reports 14 (2), 199-205, 2013 | 77 | 2013 |
Catalytic mechanism of a mammalian Rab· RabGAP complex in atomic detail K Gavriljuk, EM Gazdag, A Itzen, C Kötting, RS Goody, K Gerwert Proceedings of the National Academy of Sciences 109 (52), 21348-21353, 2012 | 74 | 2012 |