| Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2 SF Zhou, LP Yang, ZW Zhou, YH Liu, E Chan The AAPS journal 11, 481-494, 2009 | 295 | 2009 |
| KRAS dimerization impacts MEK inhibitor sensitivity and oncogenic activity of mutant KRAS Ambrogio C, Köhler J, Zhou ZW, Wang H, Paranal R, Li J, Capelletti M ... Cell 172, 1-12, 2018 | 288* | 2018 |
| An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides Cheng J, Zhou ZW, Sheng HP, He LJ, Fan XW, He ZX, Sun T, Zhang X, Zhao RJ ... Drug Des Devel Ther. 17 (9), 33-78, 2014 | 288* | 2014 |
| Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development SF Zhou, ZW Zhou, LP Yang, JP Cai Current medicinal chemistry 16 (27), 3480-3675, 2009 | 253 | 2009 |
| Identification of drugs that interact with herbs in drug development SF Zhou, ZW Zhou, CG Li, X Chen, X Yu, CC Xue, A Herington Drug discovery today 12 (15-16), 664-673, 2007 | 219 | 2007 |
| Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in … Qin Y, Zhou ZW, Pan ST, He ZX, Zhang X, Qiu JX, Duan W, Yang T, Zhou SF Toxicology, 62-76, 2014 | 207* | 2014 |
| In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice) XQ Yu, CC Xue, ZW Zhou, CG Li, YM Du, J Liang, SF Zhou Life sciences 82 (1-2), 68-78, 2008 | 184 | 2008 |
| Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells YC Li, SM He, ZX He, M Li, Y Yang, JX Pang, X Zhang, K Chow, Q Zhou, ... Cancer Letters 344 (2), 239-259, 2014 | 178 | 2014 |
| Polymorphisms of human cytochrome P450 2C9 and the functional relevance SF Zhou, ZW Zhou, M Huang Toxicology 278 (2), 165-188, 2010 | 169 | 2010 |
| Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells. Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF Drug Des Devel Ther. 9, 1601-26, 2015 | 148* | 2015 |
| An update on the clinical pharmacology of the dipeptidyl peptidase 4 inhibitor alogliptin used for the treatment of type 2 diabetes mellitus. Chen XW, He ZX, Zhou ZW, Yang T, Zhang X, Yang YX, Duan W, Zhou SF Clin Exp Pharmacol Physiol., [Epub ahead of print], 2015 | 140 | 2015 |
| Clinical pharmacology of dipeptidyl peptidase 4 inhibitors indicated for the treatment of type 2 diabetes mellitus Chen XW, He ZX, Zhou ZW, Yang T, Zhang X, Yang YX, Duan W, Zhou SF Clin Exp Pharmacol Physiol., [Epub ahead of print], 2015 | 140* | 2015 |
| Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells. Zhou ZW, Li XX, He ZX, Pan ST, Yang Y, Zhang X, Chow K, Yang T, Qiu JX, Zhou ... Drug Des Devel Ther. 9, 1511-54., 2015 | 128* | 2015 |
| Human CYP2C8: structure, substrate specificity, inhibitor selectivity, inducers and polymorphisms XS Lai, LP Yang, XT Li, JP Liu, ZW Zhou, SF Zhou Current drug metabolism 10 (9), 1009-1047, 2009 | 124 | 2009 |
| Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge XY Yu, SG Lin, ZW Zhou, X Chen, J Liang, PQ Liu, W Duan, B Chowbay, ... Current drug metabolism 8 (4), 325-340, 2007 | 98 | 2007 |
| Pro-apoptotic and pro-autophagic effects of the AURKA inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated … Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX ... Drug Des Devel Ther 9, 1555-84, 2015 | 92* | 2015 |
| Overview of clinically approved oral antidiabetic agents for the treatment of type 2 diabetes mellitus ZX He, ZW Zhou, Y Yang, T Yang, SY Pan, JX Qiu, SF Zhou Clinical and experimental pharmacology and physiology 42 (2), 125-138, 2015 | 91 | 2015 |
| Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells. Ding YH, Zhou ZW, Ha CF, Zhang XY, Pan ST, He ZX, Edelman JL, Wang D, Yang ... Drug Des Devel Ther. 9 (9), 425-64, 2015 | 90* | 2015 |
| Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human … Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang ... Drug Des Devel Ther. 17 (9), 575-601, 2015 | 88* | 2015 |
| Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine. He ZX, Chen XW, Zhou ZW, Zhou SF Drug Metab Rev., 1-50 [Epub ahead of print], 2015 | 83* | 2015 |