Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4724 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2655 | 2019 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2316 | 2011 |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2254 | 2011 |
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease B Zhang, C Gaiteri, LG Bodea, Z Wang, J McElwee, AA Podtelezhnikov, ... Cell 153 (3), 707-720, 2013 | 1846 | 2013 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 1006 | 2017 |
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor KJ Ressler, KB Mercer, B Bradley, T Jovanovic, A Mahan, K Kerley, ... Nature 470 (7335), 492-497, 2011 | 917 | 2011 |
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease KD Coon, AJ Myers, DW Craig, JA Webster, JV Pearson, DH Lince, ... Journal of Clinical Psychiatry 68 (4), 613, 2007 | 739 | 2007 |
GAB2 alleles modify Alzheimer's risk in APOE ɛ4 carriers EM Reiman, JA Webster, AJ Myers, J Hardy, T Dunckley, VL Zismann, ... Neuron 54 (5), 713-720, 2007 | 586 | 2007 |
A survey of genetic human cortical gene expression AJ Myers, JR Gibbs, JA Webster, K Rohrer, A Zhao, L Marlowe, M Kaleem, ... Nature genetics 39 (12), 1494-1499, 2007 | 574 | 2007 |
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ... Archives of neurology 67 (12), 1473-1484, 2010 | 523 | 2010 |
Susceptibility locus for Alzheimer's disease on chromosome 10 A Myers, P Holmans, H Marshall, J Kwon, D Meyer, D Ramic, S Shears, ... Science 290 (5500), 2304-2305, 2000 | 498 | 2000 |
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013 | 423 | 2013 |
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias GW Beecham, K Hamilton, AC Naj, ER Martin, M Huentelman, AJ Myers, ... PLoS genetics 10 (9), e1004606, 2014 | 387 | 2014 |
Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study EM Reiman, JF Arboleda-Velasquez, YT Quiroz, MJ Huentelman, ... Nature communications 11 (1), 667, 2020 | 380 | 2020 |
Genetic control of human brain transcript expression in Alzheimer disease JA Webster, JR Gibbs, J Clarke, M Ray, W Zhang, P Holmans, K Rohrer, ... The American Journal of Human Genetics 84 (4), 445-458, 2009 | 370 | 2009 |
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration AM Pittman, AJ Myers, P Abou-Sleiman, HC Fung, M Kaleem, L Marlowe, ... Journal of medical genetics 42 (11), 837-846, 2005 | 325 | 2005 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 311 | 2016 |
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals JJ Corneveaux, AJ Myers, AN Allen, JJ Pruzin, M Ramirez, A Engel, ... Human molecular genetics 19 (16), 3295-3301, 2010 | 308 | 2010 |
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts AJ Myers, AM Pittman, AS Zhao, K Rohrer, M Kaleem, L Marlowe, A Lees, ... Neurobiology of disease 25 (3), 561-570, 2007 | 292 | 2007 |