Прати
Matilda S. Newton
Matilda S. Newton
Post Doctoral Fellow, University of Colorado
Верификована је имејл адреса на colorado.edu
Наслов
Навело
Навело
Година
Enzyme evolution: innovation is easy, optimization is complicated
MS Newton, VL Arcus, ML Gerth, WM Patrick
Current opinion in structural biology 48, 110-116, 2018
982018
In Vitro Selection of Peptides and Proteins—Advantages of mRNA Display
MS Newton, Y Cabezas-Perusse, CL Tong, B Seelig
ACS Synthetic Biology 9 (2), 181-190, 2019
922019
Rapid bursts and slow declines: on the possible evolutionary trajectories of enzymes
MS Newton, VL Arcus, WM Patrick
Journal of The Royal Society Interface 12 (107), 20150036, 2015
352015
Structural and functional innovations in the real-time evolution of new (βα) 8 barrel enzymes
MS Newton, X Guo, A Söderholm, J Näsvall, P Lundström, DI Andersson, ...
Proceedings of the National Academy of Sciences 114 (18), 4727-4732, 2017
342017
How to recruit a promiscuous enzyme to serve a new function
SD Copley, MS Newton, KA Widney
Biochemistry 62 (2), 300-308, 2022
232022
Two-step ligand binding in a (βα) 8 barrel enzyme-substrate-bound structures shed new light on the catalytic cycle of HisA
A Söderholm, X Guo, MS Newton, GB Evans, J Näsvall, WM Patrick, ...
Journal of Biological Chemistry, jbc. M115. 678086, 2015
192015
Genetic Code Evolution Investigated through the Synthesis and Characterisation of Proteins from Reduced‐Alphabet Libraries
MS Newton, DJ Morrone, KH Lee, B Seelig
ChemBioChem 20 (6), 846-856, 2019
162019
A method for generating user-defined circular single-stranded DNA from plasmid DNA using Golden Gate intramolecular ligation
IK Strawn, PJ Steiner, MS Newton, ZT Baumer, TA Whitehead
Biotechnology and Bioengineering, 2023
62023
Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa: Decarboxylation is not essential for indole formation
A Söderholm, MS Newton, WM Patrick, M Selmer
Journal of Biological Chemistry 295 (47), 15948-15956, 2020
42020
On the Evolution of Catalysis: The changing kinetics of core metabolic enzymes
MS Newton
University of Otago, 2015
32015
Cell survival enabled by leakage of a labile metabolic intermediate
E Medina-Carmona, LI Gutierrez-Rus, F Manssour-Triedo, MS Newton, ...
Molecular Biology and Evolution 40 (3), msad032, 2023
22023
Engineered Stop and Go T7 RNA Polymerases
ZT Baumer, MS Newton, L Löfstrand, GN Carpio Paucar, NG Farny, ...
ACS Synthetic Biology, 2024
2024
Challenging a decades-old paradigm: ProB and ProA do not channel the unstable intermediate in proline synthesis after all
MS Newton, AL Azadeh, AB Morgenthaler, SD Copley
Proceedings of the National Academy of Sciences 121 (46), e2413673121, 2024
2024
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