| Structure-based discovery of opioid analgesics with reduced side effects A Manglik, H Lin, DK Aryal, JD McCorvy, D Dengler, G Corder, A Levit, ... Nature 537 (7619), 185-190, 2016 | 1028 | 2016 |
| Ultra-large library docking for discovering new chemotypes J Lyu, S Wang, TE Balius, I Singh, A Levit, YS Moroz, MJ O’Meara, T Che, ... Nature 566 (7743), 224-229, 2019 | 880 | 2019 |
| Crystal structure of an LSD-bound human serotonin receptor D Wacker, S Wang, JD McCorvy, RM Betz, AJ Venkatakrishnan, A Levit, ... Cell 168 (3), 377-389. e12, 2017 | 506 | 2017 |
| Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone S Wang, T Che, A Levit, BK Shoichet, D Wacker, BL Roth Nature 555 (7695), 269-273, 2018 | 470 | 2018 |
| BitterDB: a database of bitter compounds A Wiener, M Shudler, A Levit, MY Niv Nucleic acids research 40 (D1), D413-D419, 2012 | 298 | 2012 |
| D4 dopamine receptor high-resolution structures enable the discovery of selective agonists S Wang, D Wacker, A Levit, T Che, RM Betz, JD McCorvy, ... Science 358 (6361), 381-386, 2017 | 242 | 2017 |
| Structural identification of a hotspot on CFTR for potentiation F Liu, Z Zhang, A Levit, J Levring, KK Touhara, BK Shoichet, J Chen Science 364 (6446), 1184-1188, 2019 | 236 | 2019 |
| Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity AL Kaplan, DN Confair, K Kim, X Barros-Álvarez, RM Rodriguiz, Y Yang, ... Nature 610 (7932), 582-591, 2022 | 178 | 2022 |
| The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14 A Levit, S Nowak, M Peters, A Wiener, W Meyerhof, M Behrens, MY Niv The FASEB Journal 28 (3), 1181-1197, 2014 | 133 | 2014 |
| The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands S Born, A Levit, MY Niv, W Meyerhof, M Behrens Journal of Neuroscience 33 (1), 201-213, 2013 | 116 | 2013 |
| Homology modeling of G-protein-coupled receptors with X-ray structures on the rise T Yarnitzky, A Levit, MY Niv Curr Opin Drug Discov Devel 13 (3), 317-325, 2010 | 110 | 2010 |
| Comparing Class A GPCRs to bitter taste receptors: Structural motifs, ligand interactions and agonist-to-antagonist ratios A Di Pizio, A Levit, M Slutzki, M Behrens, R Karaman, MY Niv Methods in cell biology 132, 401-427, 2016 | 99 | 2016 |
| Induction of endothelin-2 expression by luteinizing hormone and hypoxia: possible role in bovine corpus luteum formation E Klipper, A Levit, Y Mastich, B Berisha, D Schams, R Meidan Endocrinology 151 (4), 1914-1922, 2010 | 75 | 2010 |
| Stargazin involvement with bipolar disorder and response to lithium treatment G Silberberg, A Levit, D Collier, DS Clair, J Munro, RW Kerwin, L Tondo, ... Pharmacogenetics and genomics 18 (5), 403-412, 2008 | 71 | 2008 |
| Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14 S Nowak, A Di Pizio, A Levit, MY Niv, W Meyerhof, M Behrens Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (10), 2162-2173, 2018 | 66 | 2018 |
| Homology model-assisted elucidation of binding sites in GPCRs A Levit, D Barak, M Behrens, W Meyerhof, MY Niv Membrane protein structure and dynamics: Methods and protocols, 179-205, 2012 | 51 | 2012 |
| Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs A Levit, T Yarnitzky, A Wiener, R Meidan, MY Niv PloS one 6 (11), e27990, 2011 | 49 | 2011 |
| A complete genetic association scan of the 22q11 deletion region and functional evidence reveal an association between DGCR2 and schizophrenia S Shifman, A Levit, ML Chen, CH Chen, M Bronstein, A Weizman, B Yakir, ... Human genetics 120, 160-170, 2006 | 49 | 2006 |
| Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor A Levit Kaplan, RT Strachan, JM Braz, V Craik, S Slocum, T Mangano, ... Journal of medicinal chemistry 65 (5), 4201-4217, 2022 | 31 | 2022 |
| Predicting GPCR promiscuity using binding site features A Levit, T Beuming, G Krilov, W Sherman, MY Niv Journal of chemical information and modeling 54 (1), 184-194, 2014 | 28 | 2014 |
Brian ShoichetProfessor of Pharmaceutical Chemistry, University of California, San FranciscoВерификована је имејл адреса на cgl.ucsf.edu