m6A RNA modification controls cell fate transition in mammalian embryonic stem cells PJ Batista, B Molinie, J Wang, K Qu, J Zhang, L Li, DM Bouley, E Lujan, ... Cell stem cell 15 (6), 707-719, 2014 | 1244 | 2014 |
Reactive nitrogen species in the chemical biology of inflammation PC Dedon, SR Tannenbaum Archives of biochemistry and biophysics 423 (1), 12-22, 2004 | 743 | 2004 |
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice LB Meira, JM Bugni, SL Green, CW Lee, B Pang, D Borenshtein, ... The Journal of clinical investigation 118 (7), 2516-2525, 2008 | 693 | 2008 |
A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress CTY Chan, M Dyavaiah, MS DeMott, K Taghizadeh, PC Dedon, TJ Begley PLoS genetics 6 (12), e1001247, 2010 | 502 | 2010 |
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins CTY Chan, YLJ Pang, W Deng, IR Babu, M Dyavaiah, TJ Begley, ... Nature communications 3 (1), 937, 2012 | 477 | 2012 |
m6A-LAIC-seq reveals the census and complexity of the m6A epitranscriptome B Molinie, J Wang, KS Lim, R Hillebrand, Z Lu, N Van Wittenberghe, ... Nature methods 13 (8), 692-698, 2016 | 398 | 2016 |
N6-methyladenosine RNA modification regulates shoot stem cell fate in Arabidopsis L Shen, Z Liang, X Gu, Y Chen, ZWN Teo, X Hou, WM Cai, PC Dedon, ... Developmental cell 38 (2), 186-200, 2016 | 388 | 2016 |
Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates P Lonkar, PC Dedon International journal of cancer 128 (9), 1999-2009, 2011 | 350 | 2011 |
Characterization of the reactions of platinum antitumor agents with biologic and nonbiologic sulfur-containing nucleophiles PC Dedon, RF Borch Biochemical pharmacology 36 (12), 1955-1964, 1987 | 341 | 1987 |
Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin PC Dedon, IH Goldberg Chemical research in toxicology 5 (3), 311-332, 1992 | 324 | 1992 |
Phosphorothioation of DNA in bacteria by dnd genes L Wang, S Chen, T Xu, K Taghizadeh, JS Wishnok, X Zhou, D You, ... Nature chemical biology 3 (11), 709-710, 2007 | 315 | 2007 |
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry D Su, CTY Chan, C Gu, KS Lim, YH Chionh, ME McBee, BS Russell, ... Nature protocols 9 (4), 828-841, 2014 | 294 | 2014 |
Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens JG Fox, Y Feng, EJ Theve, AR Raczynski, JLA Fiala, AL Doernte, ... Gut 59 (01), 88-97, 2010 | 276 | 2010 |
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer A Mangerich, CG Knutson, NM Parry, S Muthupalani, W Ye, E Prestwich, ... Proceedings of the National Academy of Sciences 109 (27), E1820-E1829, 2012 | 275 | 2012 |
Effect of Diethyldithiocarbamate on cis-Diamminedichloroplatinum(II)-induced Cytotoxicity, DNA Cross-Linking, and γ-Glutamyl Transpeptidase Inhibition DL Bodenner, PC Dedon, PC Keng, RF Borch Cancer research 46 (6), 2745-2750, 1986 | 263 | 1986 |
The chemical toxicology of 2-deoxyribose oxidation in DNA PC Dedon Chemical research in toxicology 21 (1), 206-219, 2008 | 254 | 2008 |
Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal PC Dedon, JP Plastaras, CA Rouzer, LJ Marnett Proceedings of the National Academy of Sciences 95 (19), 11113-11116, 1998 | 253 | 1998 |
Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA B Pang, JL McFaline, NE Burgis, M Dong, K Taghizadeh, MR Sullivan, ... Proceedings of the National Academy of Sciences 109 (7), 2319-2324, 2012 | 236 | 2012 |
Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival D Fu, JAN Brophy, CTY Chan, KA Atmore, U Begley, RS Paules, ... Molecular and cellular biology 30 (10), 2449-2459, 2010 | 232 | 2010 |
Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence P Rai, TT Onder, JJ Young, JL McFaline, B Pang, PC Dedon, ... Proceedings of the National Academy of Sciences 106 (1), 169-174, 2009 | 226 | 2009 |