Joanne (Hulett) Hildebrand

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	Све	Од 2020
Наводи	5084	3094
h-индекс	30	26
i10-индекс	41	37

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Коаутори

John SilkeProfessor, The Walter and Eliza Hall InstituteВерификована је имејл адреса на latrobe.edu.au
Andrew I. WebbAssociate Professor - The Walter and Eliza Hall InstituteВерификована је имејл адреса на wehi.edu.au
jeff babonwalter and eliza hall instituteВерификована је имејл адреса на wehi.edu.au
Najoua LalaouiGroup Leader, Peter MacCallum Cancer CenterВерификована је имејл адреса на petermac.org
Jian-Guo ZhangSenior Research Scientist, The Walter and Eliza Hall Institute of Medical Research, MelbourneВерификована је имејл адреса на wehi.edu.au
Renwick CJ DobsonProfessor of Chemical Biology, School of Biological Sciences, University of CanterburyВерификована је имејл адреса на canterbury.ac.nz
Paul GooleyUniversity of MelbourneВерификована је имејл адреса на unimelb.edu.au
Silvia Alvarez-DiazPostdoctoral Fellow at Walter and Eliza Hall Institute of Medical ResearchВерификована је имејл адреса на wehi.edu.au
Andreas StrasserThe Walter and Eliza Hall InstituteВерификована је имејл адреса на wehi.edu.au
Nicos A NicolaDivision Head, Walter and Eliza Hall InstituteВерификована је имејл адреса на wehi.edu.au
Andrew J. PerryMonash UniversityВерификована је имејл адреса на monash.edu
Vladimir LikicВерификована је имејл адреса на spin.net.au
Martin ScanlonProfessor of Medicinal Chemistry, Monash UniversityВерификована је имејл адреса на monash.edu
Wei-Hao LinCarnegie Mellon UniversityВерификована је имејл адреса на cs.cmu.edu
Zhenghua LuoThe Ohio State UniversityВерификована је имејл адреса на osumc.edu
Ryan ListerUniversity of Western Australia; Harry Perkins Institute of Medical ResearchВерификована је имејл адреса на uwa.edu.au
Nicolas (Nic) TaylorAssociate Professor, The University of Western AustraliaВерификована је имејл адреса на uwa.edu.au
A. Harvey MillarARC Laureate Fellow | ARC Centre of Excellence in Plant Energy Biology, The University of WesternВерификована је имејл адреса на uwa.edu.au
Ross F WallerUniversity of CambridgeВерификована је имејл адреса на cam.ac.uk
Dr Pooja SharmaHarvard Medical School, Amgen, Monash University, WEHI-Melbourne University

Прати

Joanne (Hulett) Hildebrand

Medical Science Liaison, Eli Lilly ANZ. Former Senior Research Scientist, WEHI

Нема верификоване имејл адресе - Почетна страница

Inflammation Necroptosis Cell death MLKL


Наслов Сортирај по наводима Сортирај по години Сортирај по наслову	Навело Навело	Година
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013	1263	2013
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014	608	2014
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ... Nature communications 11 (1), 3151, 2020	285	2020
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ... Nature communications 9 (1), 2422, 2018	195	2018
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation JS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ... Nature microbiology 2 (4), 1-10, 2017	192	2017
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death AV Jacobsen, KN Lowes, MC Tanzer, IS Lucet, JM Hildebrand, EJ Petrie, ... Cell death & disease 7 (1), e2051-e2051, 2016	170	2016
Convergent evolution of receptors for protein import into mitochondria AJ Perry, JM Hulett, VA Likić, T Lithgow, PR Gooley Current Biology 16 (3), 221-229, 2006	144	2006
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Nature communications 6 (1), 6442, 2015	139	2015
Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions JM Hildebrand, Z Yi, CM Buchta, J Poovassery, LL Stunz, GA Bishop Immunological reviews 244 (1), 55-74, 2011	123	2011
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling JM Hildebrand, Z Luo, MK Manske, T Price-Troska, SC Ziesmer, W Lin, ... Journal of Experimental Medicine 207 (12), 2569-2579, 2010	123	2010
The transmembrane segment of Tom20 is recognized by Mim1 for docking to the mitochondrial TOM complex JM Hulett, F Lueder, NC Chan, AJ Perry, P Wolynec, VA Likić, PR Gooley, ... Journal of molecular biology 376 (3), 694-704, 2008	122	2008
Evolutionary divergence of the necroptosis effector MLKL MC Tanzer, I Matti, JM Hildebrand, SN Young, A Wardak, A Tripaydonis, ... Cell Death & Differentiation 23 (7), 1185-1197, 2016	120	2016
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL JM Murphy, IS Lucet, JM Hildebrand, MC Tanzer, SN Young, P Sharma, ... Biochemical Journal 457 (3), 369-377, 2014	115	2014
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop MC Tanzer, A Tripaydonis, AI Webb, SN Young, LN Varghese, C Hall, ... Biochemical Journal 471 (2), 255-265, 2015	112	2015
Protein import into mitochondria: origins and functions today R Lister, JM Hulett, T Lithgow, J Whelan Molecular membrane biology 22 (1-2), 87-100, 2005	109	2005
Insane in the membrane: a structural perspective of MLKL function in necroptosis EJ Petrie, JM Hildebrand, JM Murphy Immunology and cell biology 95 (2), 152-159, 2017	86	2017
Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted MD Stutz, S Ojaimi, C Allison, S Preston, P Arandjelovic, JM Hildebrand, ... Cell Death & Differentiation 25 (5), 951-965, 2018	82	2018
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis SE Garnish, Y Meng, A Koide, JJ Sandow, E Denbaum, AV Jacobsen, ... Nature communications 12 (1), 2211, 2021	81	2021
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction JM Hildebrand, M Kauppi, IJ Majewski, Z Liu, AJ Cox, S Miyake, EJ Petrie, ... Nature communications 11 (1), 3150, 2020	79	2020
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs S Murai, Y Yamaguchi, Y Shirasaki, M Yamagishi, R Shindo, ... Nature communications 9 (1), 4457, 2018	76	2018

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