Antibody recognition of a unique tumor-specific glycopeptide antigen CL Brooks, A Schietinger, SN Borisova, P Kufer, M Okon, T Hirama, ... Proceedings of the National Academy of Sciences 107 (22), 10056-10061, 2010 | 112 | 2010 |
Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen M Movahedin, TM Brooks, NT Supekar, N Gokanapudi, GJ Boons, ... Glycobiology 27 (7), 677-687, 2017 | 78 | 2017 |
Epitope mapping of antibody-antigen interactions with X-ray crystallography M Toride King, CL Brooks Epitope Mapping Protocols, 13-27, 2018 | 63 | 2018 |
Analysis of cross-reactive and specific anti-carbohydrate antibodies against lipopolysaccharide from Chlamydophila psittaci S Gerstenbruch, CL Brooks, P Kosma, L Brade, CR MacKenzie, SV Evans, ... Glycobiology 20 (4), 461-472, 2010 | 47 | 2010 |
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS K Gomery, S Müller-Loennies, CL Brooks, L Brade, P Kosma, F Di Padova, ... Proceedings of the National Academy of Sciences 109 (51), 20877-20882, 2012 | 42 | 2012 |
Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes CL Brooks, S Müller-Loennies, L Brade, P Kosma, T Hirama, ... Journal of molecular biology 377 (2), 450-468, 2008 | 41 | 2008 |
Rapid expression screening of eukaryotic membrane proteins in Pichia pastoris CL Brooks, M Morrison, M Joanne Lemieux Protein Science 22 (4), 425-433, 2013 | 39 | 2013 |
Insights into substrate gating in H. influenzae rhomboid CL Brooks, C Lazareno-Saez, JS Lamoureux, MW Mak, MJ Lemieux Journal of molecular biology 407 (5), 687-697, 2011 | 38 | 2011 |
The structure of lactoferrin-binding protein B from Neisseria meningitidis suggests roles in iron acquisition and neutralization of host defences CL Brooks, E Arutyunova, MJ Lemieux Structural Biology and Crystallization Communications 70 (10), 1312-1317, 2014 | 36 | 2014 |
Protein kinase A affects Galleria mellonella (Insecta: Lepidoptera) larval haemocyte non‐self responses CL Brooks, GB Dunphy Immunology and Cell Biology 83 (2), 150-159, 2005 | 34 | 2005 |
Structural basis of VHH-mediated neutralization of the food-borne pathogen Listeria monocytogenes MT King, I Huh, A Shenai, TM Brooks, CL Brooks Journal of Biological Chemistry 293 (35), 13626-13635, 2018 | 33 | 2018 |
Untangling structure–function relationships in the rhomboid family of intramembrane proteases CL Brooks, MJ Lemieux Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (12), 2862-2872, 2013 | 32 | 2013 |
ImmunoPET of ovarian and pancreatic cancer with AR9. 6, a novel MUC16-targeted therapeutic antibody SK Sharma, KN Mack, A Piersigilli, J Pourat, KJ Edwards, O Keinänen, ... Clinical Cancer Research 28 (5), 948-959, 2022 | 30 | 2022 |
Role of a noncanonical disulfide bond in the stability, affinity, and flexibility of a VHH specific for the Listeria virulence factor InlB MN Mendoza, M Jian, MT King, CL Brooks Protein Science 29 (4), 990-1003, 2020 | 28 | 2020 |
Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition CL Brooks, S Müller-Loennies, SN Borisova, L Brade, P Kosma, ... Biochemistry 49 (3), 570-581, 2010 | 28 | 2010 |
Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia DW Evans, S Müller-Loennies, CL Brooks, L Brade, P Kosma, H Brade, ... Glycobiology 21 (8), 1049-1059, 2011 | 25 | 2011 |
Crystal structure of the N-lobe of lactoferrin binding protein B from Moraxella bovis1 E Arutyunova, CL Brooks, A Beddek, MW Mak, AB Schryvers, MJ Lemieux Biochemistry and cell biology 90 (3), 351-361, 2012 | 23 | 2012 |
Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker B White, M Patterson, S Karnwal, CL Brooks Proteins: Structure, Function, and Bioinformatics 90 (5), 1210-1218, 2022 | 21 | 2022 |
Immunological functions and evolutionary emergence of heavy-chain antibodies CL Brooks, MA Rossotti, KA Henry Trends in immunology 39 (12), 956-960, 2018 | 21 | 2018 |
Directed evolution of the Escherichia coli cAMP receptor protein at the cAMP pocket SM Gunasekara, MN Hicks, J Park, CL Brooks, J Serate, CV Saunders, ... Journal of Biological Chemistry 290 (44), 26587-26596, 2015 | 20 | 2015 |