Catalytic meta-selective CH functionalization to construct quaternary carbon centres N Press, A Paterson, S John-Campbell, M Mahon, C Frost Chemical Communications 51 (64), 2015 | 174 | 2015 |
Catalytic meta-selective C–H functionalization to construct quaternary carbon centres AJ Paterson, S St John-Campbell, MF Mahon, NJ Press, CG Frost Chemical Communications 51 (64), 12807-12810, 2015 | 174 | 2015 |
An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model ER Jarman, VS Khambata, C Cope, P Jones, J Roger, LY Ye, N Duggan, ... American journal of respiratory cell and molecular biology 50 (1), 158-169, 2014 | 138 | 2014 |
Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease KH Banner, NJ Press British journal of pharmacology 157 (6), 892-906, 2009 | 130 | 2009 |
Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect CS Stevenson, K Coote, R Webster, H Johnston, HC Atherton, A Nicholls, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (3 …, 2005 | 108 | 2005 |
A common intracellular allosteric binding site for antagonists of the CXCR2 receptor K Salchow, ME Bond, SC Evans, NJ Press, SJ Charlton, PA Hunt, ... British journal of pharmacology 159 (7), 1429-1439, 2010 | 94 | 2010 |
Heparin-steroid conjugates: new angiogenesis inhibitors with antitumor activity in mice PE Thorpe, EJ Derbyshire, SP Andrade, N Press, PP Knowles, S King, ... Cancer research 53 (13), 3000-3007, 1993 | 81 | 1993 |
2 PDE4 inhibitors–a review of the current field NJ Press, KH Banner Progress in medicinal chemistry 47, 37-74, 2009 | 80 | 2009 |
Nitrone dipolar cycloaddition routes to piperidines and indolizidines. Part 9. Formal synthesis of (−)-pinidine and total synthesis of (−)-histrionicotoxin,(+)-histrionicotoxin … EC Davison, ME Fox, AB Holmes, SD Roughley, CJ Smith, GM Williams, ... Journal of the Chemical Society, Perkin Transactions 1, 1494-1514, 2002 | 64 | 2002 |
α-Halo carbonyls enable meta selective primary, secondary and tertiary C–H alkylations by ruthenium catalysis AJ Paterson, CJ Heron, CL McMullin, MF Mahon, NJ Press, CG Frost Organic & biomolecular chemistry 15 (28), 5993-6000, 2017 | 55 | 2017 |
The Crystalline Sponge Method: A Systematic Study of the Reproducibility of Simple Aromatic Molecule Encapsulation and Guest–Host Interactions LM Hayes, CE Knapp, KY Nathoo, NJ Press, DA Tocher, CJ Carmalt Crystal Growth & Design 16 (6), 3465-3472, 2016 | 48 | 2016 |
Synthesis of a Protected (±)-Calicheamicinone Derivative by Sequential Introduction of Functionality into the Bicyclo [7.3. 1] enediyne Core Structure P Magnus, GF Miknis, NJ Press, D Grandjean, GM Taylor, J Harling Journal of the American Chemical Society 119 (29), 6739-6748, 1997 | 44 | 1997 |
A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential NJ Press, RJ Taylor, JD Fullerton, P Tranter, C McCarthy, TH Keller, ... Bioorganic & medicinal chemistry letters 15 (12), 3081-3085, 2005 | 40 | 2005 |
Targeting the serotonin pathway for the treatment of pulmonary arterial hypertension M Thomas, L Ciuclan, MJ Hussey, NJ Press Pharmacology & therapeutics 138 (3), 409-417, 2013 | 38 | 2013 |
Aminothaizoles and their use as adenosine receptor antagonists NJ Press, RJ Taylor US Patent 7,109,202, 2006 | 38 | 2006 |
CGH2466, a combined adenosine receptor antagonist, p38 mitogen‐activated protein kinase and phosphodiesterase type 4 inhibitor with potent in vitro and in vivo anti … A Trifilieff, TH Keller, NJ Press, T Howe, P Gedeck, D Beer, C Walker British journal of pharmacology 144 (7), 1002-1010, 2005 | 35 | 2005 |
Solubility-driven optimization of phosphodiesterase-4 inhibitors leading to a clinical candidate NJ Press, RJ Taylor, JD Fullerton, P Tranter, C McCarthy, TH Keller, ... Journal of medicinal chemistry 55 (17), 7472-7479, 2012 | 34 | 2012 |
The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists DW Porter, M Bradley, Z Brown, R Canova, S Charlton, B Cox, P Hunt, ... Bioorganic & medicinal chemistry letters 24 (1), 72-76, 2014 | 31 | 2014 |
Therapeutic potential of adenosine receptor antagonists and agonists NJ Press, S Gessi, PA Borea, R Polosa Expert opinion on therapeutic patents 17 (8), 979-991, 2007 | 31 | 2007 |
The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists DW Porter, M Bradley, Z Brown, SJ Charlton, B Cox, P Hunt, D Janus, ... Bioorganic & medicinal chemistry letters 24 (15), 3285-3290, 2014 | 30 | 2014 |