Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer E Tran, S Turcotte, A Gros, PF Robbins, YC Lu, ME Dudley, ... Science 344 (6184), 641-645, 2014 | 2534 | 2014 |
T-cell transfer therapy targeting mutant KRAS in cancer E Tran, PF Robbins, YC Lu, TD Prickett, JJ Gartner, L Jia, A Pasetto, ... New England Journal of Medicine 375 (23), 2255-2262, 2016 | 1395 | 2016 |
PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors A Gros, PF Robbins, X Yao, YF Li, S Turcotte, E Tran, JR Wunderlich, ... The Journal of clinical investigation 124 (5), 2246-2259, 2014 | 1176 | 2014 |
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients A Gros, MR Parkhurst, E Tran, A Pasetto, PF Robbins, S Ilyas, TD Prickett, ... Nature medicine 22 (4), 433-438, 2016 | 906 | 2016 |
Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 897 | 2017 |
Immunogenicity of somatic mutations in human gastrointestinal cancers E Tran, M Ahmadzadeh, YC Lu, A Gros, S Turcotte, PF Robbins, ... Science 350 (6266), 1387-1390, 2015 | 804 | 2015 |
'Final common pathway'of human cancer immunotherapy: targeting random somatic mutations E Tran, PF Robbins, SA Rosenberg Nature immunology 18 (3), 255-262, 2017 | 471 | 2017 |
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia E Tran, D Chinnasamy, Z Yu, RA Morgan, CCR Lee, NP Restifo, ... Journal of Experimental Medicine 210 (6), 1125-1135, 2013 | 430 | 2013 |
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics JG Crompton, M Sukumar, R Roychoudhuri, D Clever, A Gros, RL Eil, ... Cancer research 75 (2), 296-305, 2015 | 385 | 2015 |
Neoantigen T-cell receptor gene therapy in pancreatic cancer R Leidner, N Sanjuan Silva, H Huang, D Sprott, C Zheng, YP Shih, ... New England Journal of Medicine 386 (22), 2112-2119, 2022 | 379 | 2022 |
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers P Malekzadeh, A Pasetto, PF Robbins, MR Parkhurst, BC Paria, L Jia, ... The Journal of clinical investigation 129 (3), 2021 | 256 | 2021 |
Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers MR Parkhurst, PF Robbins, E Tran, TD Prickett, JJ Gartner, L Jia, G Ivey, ... Cancer discovery 9 (8), 1022-1035, 2019 | 246 | 2019 |
A novel chimeric antigen receptor against prostate stem cell antigen mediates tumor destruction in a humanized mouse model of pancreatic cancer D Abate-Daga, KH Lagisetty, E Tran, Z Zheng, L Gattinoni, Z Yu, ... Human gene therapy 25 (12), 1003-1012, 2014 | 225 | 2014 |
Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy R Yossef, E Tran, DC Deniger, A Gros, A Pasetto, MR Parkhurst, ... JCI insight 3 (19), e122467, 2018 | 218 | 2018 |
Targeting of HPV-16+ epithelial cancer cells by TCR gene engineered T cells directed against E6 LM Draper, MLM Kwong, A Gros, S Stevanović, E Tran, S Kerkar, ... Clinical Cancer Research 21 (19), 4431-4439, 2015 | 196 | 2015 |
Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes A Gros, E Tran, MR Parkhurst, S Ilyas, A Pasetto, EM Groh, PF Robbins, ... The Journal of clinical investigation 129 (11), 4992-5004, 2019 | 160 | 2019 |
Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells RE Beard, Z Zheng, KH Lagisetty, WR Burns, E Tran, SM Hewitt, ... Journal for immunotherapy of cancer 2, 1-11, 2014 | 156 | 2014 |
Immunologic recognition of a shared p53 mutated neoantigen in a patient with metastatic colorectal cancer W Lo, M Parkhurst, PF Robbins, E Tran, YC Lu, L Jia, JJ Gartner, ... Cancer immunology research 7 (4), 534-543, 2019 | 150 | 2019 |
Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells R Duhen, C Ballesteros-Merino, AK Frye, E Tran, V Rajamanickam, ... Nature communications 12 (1), 1047, 2021 | 137 | 2021 |
Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer AJ Gunderson, V Rajamanickam, C Bui, B Bernard, J Pucilowska, ... Oncoimmunology 10 (1), 1900635, 2021 | 129 | 2021 |