Biocatalytic ketone reduction—a powerful tool for the production of chiral alcohols—part I: processes with isolated enzymes K Goldberg, K Schroer, S Lütz, A Liese Applied microbiology and biotechnology 76, 237-248, 2007 | 404 | 2007 |
Metabolomics: current state and evolving methodologies and tools M Oldiges, S Lütz, S Pflug, K Schroer, N Stein, C Wiendahl Applied microbiology and biotechnology 76, 495-511, 2007 | 305 | 2007 |
Biocatalytic ketone reduction—a powerful tool for the production of chiral alcohols—part II: whole-cell reductions K Goldberg, K Schroer, S Lütz, A Liese Applied Microbiology and Biotechnology 76, 249-255, 2007 | 285 | 2007 |
Recombinant human cytochrome P450 monooxygenases for drug metabolite synthesis K Schroer, M Kittelmann, S Lütz Biotechnology and bioengineering 106 (5), 699-706, 2010 | 137 | 2010 |
High cell density cultivation of recombinant yeasts and bacteria under non-pressurized and pressurized conditions in stirred tank bioreactors A Knoll, S Bartsch, B Husemann, P Engel, K Schroer, B Ribeiro, ... Journal of biotechnology 132 (2), 167-179, 2007 | 112 | 2007 |
Continuous asymmetric ketone reduction processes with recombinant Escherichia coli K Schroer, U Mackfeld, IAW Tan, C Wandrey, F Heuser, S Bringer-Meyer, ... Journal of biotechnology 132 (4), 438-444, 2007 | 82 | 2007 |
Engineering the Pichia pastoris methanol oxidation pathway for improved NADH regeneration during whole-cell biotransformation K Schroer, KP Luef, FS Hartner, A Glieder, B Pscheidt Metabolic Engineering 12 (1), 8-17, 2010 | 81 | 2010 |
Evolved aliphatic halogenases enable regiocomplementary C− H functionalization of a pharmaceutically relevant compound T Hayashi, M Ligibel, E Sager, M Voss, J Hunziker, K Schroer, ... Angewandte Chemie International Edition 58 (51), 18535-18539, 2019 | 74 | 2019 |
Metabolism and disposition of siponimod, a novel selective S1P1/S1P5 agonist, in healthy volunteers and in vitro identification of human cytochrome P450 enzymes involved in its … U Glaenzel, Y Jin, R Nufer, W Li, K Schroer, S Adam-Stitah, SP van Marle, ... Drug metabolism and disposition 46 (7), 1001-1013, 2018 | 68 | 2018 |
Enhancement of the NAD(P)(H) Pool in Escherichia coli for Biotransformation F Heuser, K Schroer, S Lütz, S Bringer‐Meyer, H Sahm Engineering in Life Sciences 7 (4), 343-353, 2007 | 65 | 2007 |
Process intensification for substrate-coupled whole cell ketone reduction by in situ acetone removal K Schroer, E Tacha, S Lütz Organic process research & development 11 (5), 836-841, 2007 | 57 | 2007 |
Metabolomics for biotransformations: intracellular redox cofactor analysis and enzyme kinetics offer insight into whole cell processes K Schroer, B Zelic, M Oldiges, S Lütz Biotechnology and bioengineering 104 (2), 251-260, 2009 | 39 | 2009 |
Absorption, distribution, metabolism, and excretion of capmatinib (INC280) in healthy male volunteers and in vitro aldehyde oxidase phenotyping of the major metabolite U Glaenzel, Y Jin, R Hansen, K Schroer, G Rahmanzadeh, U Pfaar, ... Drug Metabolism and Disposition 48 (10), 873-885, 2020 | 35 | 2020 |
Modulating chemoselectivity in a Fe (II)/α-ketoglutarate-dependent dioxygenase for the oxidative modification of a nonproteinogenic amino acid F Meyer, R Frey, M Ligibel, E Sager, K Schroer, R Snajdrova, R Buller ACS Catalysis 11 (10), 6261-6269, 2021 | 28 | 2021 |
A Continuously Operated Bimembrane Reactor Process for the Biocatalytic Production of (2R,5R)-Hexanediol K Schroer, S Lütz Organic Process Research & Development 13 (6), 1202-1205, 2009 | 24 | 2009 |
Cladosporin derivatives obtained by biotransformation provide guidance for the focused derivatization of this antimalarial lead compound A Fredenhagen, K Schroer, H Schröder, D Hoepfner, M Ligibel, ... ChemBioChem 20 (5), 650-654, 2019 | 15 | 2019 |
Evolvierte aliphatische Halogenasen ermöglichen die regiokomplementäre C‐H‐Funktionalisierung einer hochwertigen Chemikalie T Hayashi, M Ligibel, E Sager, M Voss, J Hunziker, K Schroer, ... Angewandte Chemie 131 (51), 18706-18711, 2019 | 12 | 2019 |
Definition of culture conditions for Arxula adeninivorans, a rational basis for studying heterologous gene expression in this dimorphic yeast C Stöckmann, TG Palmen, K Schroer, G Kunze, G Gellissen, J Büchs Journal of Industrial Microbiology and Biotechnology 41 (6), 965-976, 2014 | 11 | 2014 |
Enzyme engineering enables inversion of substrate stereopreference of the halogenase WelO5 M Voss, S Hüppi, D Schaub, T Hayashi, M Ligibel, E Sager, K Schroer, ... ChemCatChem 14 (24), e202201115, 2022 | 6 | 2022 |
Biocatalytic assembly of chemically modified oligonucleotides G Mann, FV Stanger, T Peschke, K Schroer, NQN Trung, N Burrer, ... Tetrahedron letters 93, 153696, 2022 | 6 | 2022 |