| Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis A Kinloch, K Lundberg, R Wait, N Wegner, NH Lim, AJW Zendman, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 360 | 2008 |
| Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4 C Gendron, M Kashiwagi, NH Lim, JJ Enghild, IB Thøgersen, C Hughes, ... Journal of Biological Chemistry 282 (25), 18294-18306, 2007 | 326 | 2007 |
| Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice B Seubert, B Grünwald, J Kobuch, H Cui, F Schelter, S Schaten, JT Siveke, ... Hepatology 61 (1), 238-248, 2015 | 225 | 2015 |
| X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding D Jozic, G Bourenkov, NH Lim, R Visse, H Nagase, W Bode, K Maskos Journal of biological chemistry 280 (10), 9578-9585, 2005 | 157 | 2005 |
| TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2 WM Wang, G Ge, NH Lim, H Nagase, DS Greenspan Biochemical journal 398 (3), 515-519, 2006 | 131 | 2006 |
| Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity K Fushimi, L Troeberg, H Nakamura, NH Lim, H Nagase Journal of biological chemistry 283 (11), 6706-6716, 2008 | 109 | 2008 |
| N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential … E Nuti, F Casalini, SI Avramova, S Santamaria, G Cercignani, L Marinelli, ... Journal of medicinal chemistry 52 (15), 4757-4773, 2009 | 83 | 2009 |
| Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications NH Lim, M Kashiwagi, R Visse, J Jones, JJ Enghild, K Brew, H Nagase Biochemical journal 431 (1), 113-122, 2010 | 76 | 2010 |
| DOTAM derivatives as active cartilage-targeting drug carriers for the treatment of osteoarthritis HY Hu, NH Lim, D Ding-Pfennigdorff, J Saas, KU Wendt, O Ritzeler, ... Bioconjugate chemistry 26 (3), 383-388, 2015 | 65 | 2015 |
| A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons A Ould-yahoui, E Tremblay, O Sbai, L Ferhat, A Bernard, E Charrat, ... PloS one 4 (12), e8289, 2009 | 65 | 2009 |
| In vivo optical imaging in arthritis—an enlightening future? LL Gompels, NH Lim, T Vincent, EM Paleolog Rheumatology 49 (8), 1436-1446, 2010 | 54 | 2010 |
| In vivo fluorescence imaging of E‐selectin: Quantitative detection of endothelial activation in a mouse model of arthritis LL Gompels, L Madden, NH Lim, JJ Inglis, E McConnell, TL Vincent, ... Arthritis & Rheumatism 63 (1), 107-117, 2011 | 53 | 2011 |
| Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation D Caglič, A Globisch, M Kindermann, NH Lim, V Jeske, HP Juretschke, ... Bioorganic & medicinal chemistry 19 (3), 1055-1061, 2011 | 51 | 2011 |
| Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity M Bekhouche, D Kronenberg, S Vadon-Le Goff, C Bijakowski, NH Lim, ... Journal of Biological Chemistry 285 (21), 15950-15959, 2010 | 45 | 2010 |
| Targeting of viral interleukin-10 with an antibody fragment specific to damaged arthritic cartilage improves its therapeutic potency C Hughes, A Sette, M Seed, F D’Acquisto, A Manzo, TL Vincent, NH Lim, ... Arthritis research & therapy 16, 1-11, 2014 | 43 | 2014 |
| In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis NH Lim, E Meinjohanns, M Meldal, G Bou-Gharios, H Nagase Osteoarthritis and cartilage 22 (6), 862-868, 2014 | 43 | 2014 |
| In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen‐induced arthritis NH Lim, E Meinjohanns, G Bou‐Gharios, LL Gompels, E Nuti, A Rossello, ... Arthritis & rheumatology 66 (3), 589-598, 2014 | 39 | 2014 |
| In vivo imaging of MMP‐13 activity using a specific polymer‐FRET peptide conjugate detects early osteoarthritis and inhibitor efficacy A Duro‐Castano, NH Lim, I Tranchant, M Amoura, F Beau, H Wieland, ... Advanced Functional Materials 28 (37), 1802738, 2018 | 35 | 2018 |
| In vivo visualization of osteoarthritic hypertrophic lesions HY Hu, NH Lim, HP Juretschke, D Ding-Pfennigdorff, P Florian, ... Chemical Science 6 (11), 6256-6261, 2015 | 27 | 2015 |
| Generation of a mouse line harboring a bi‐transgene expressing luciferase and tamoxifen‐activatable creERT2 recombinase in cartilage LL Cascio, K Liu, H Nakamura, G Chu, NH Lim, A Chanalaris, ... genesis 52 (2), 110-119, 2014 | 22 | 2014 |
