Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: Synthesis, biological evaluation, and molecular modeling … BK Srivastava, A Joharapurkar, S Raval, JZ Patel, R Soni, P Raval, A Gite, ... Journal of medicinal chemistry 50 (24), 5951-5966, 2007 | 82 | 2007 |
Chiral 1, 3, 4-oxadiazol-2-ones as highly selective FAAH inhibitors JZ Patel, T Parkkari, T Laitinen, AA Kaczor, SM Saario, JR Savinainen, ... Journal of medicinal chemistry 56 (21), 8484-8496, 2013 | 68 | 2013 |
Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A) JR Savinainen, JZ Patel, T Parkkari, D Navia-Paldanius, JJT Marjamaa, ... PLoS One 9 (10), e109869, 2014 | 56 | 2014 |
New in Vitro Tools to Study Human Constitutive Androstane Receptor (CAR) Biology: Discovery and Comparison of Human CAR Inverse Agonists J Küblbeck, J Jyrkkärinne, F Molnár, T Kuningas, J Patel, ... Molecular pharmaceutics 8 (6), 2424-2433, 2011 | 54 | 2011 |
Loratadine analogues as MAGL inhibitors JZ Patel, S Ahenkorah, M Vaara, M Staszewski, Y Adams, T Laitinen, ... Bioorganic & medicinal chemistry letters 25 (7), 1436-1442, 2015 | 49 | 2015 |
Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a CB1 receptor antagonist with in vivo antiobesity effect BK Srivastava, R Soni, JZ Patel, A Joharapurkar, N Sadhwani, ... Bioorganic & medicinal chemistry letters 19 (9), 2546-2550, 2009 | 41 | 2009 |
Optimization of 1, 2, 5‐thiadiazole carbamates as potent and selective ABHD6 inhibitors JZ Patel, TJ Nevalainen, JR Savinainen, Y Adams, T Laitinen, RS Runyon, ... ChemMedChem 10 (2), 253-265, 2015 | 39 | 2015 |
Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors AA Kaczor, KM Targowska-Duda, JZ Patel, T Laitinen, T Parkkari, ... Journal of molecular modeling 21, 1-16, 2015 | 33 | 2015 |
Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) J Korhonen, A Kuusisto, J van Bruchem, JZ Patel, T Laitinen, ... Bioorganic & Medicinal Chemistry 22 (23), 6694-6705, 2014 | 29 | 2014 |
Oxazolidinone antibacterials and our experience BK Srivastava, R Soni, JZ Patel, MR Jain, PR Patel Anti-Infective Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2008 | 27 | 2008 |
Synthesis and in vitro antibacterial activities of novel oxazolidinones BK Srivastava, MR Jain, M Solanki, R Soni, D Valani, S Gupta, B Mishra, ... European journal of medicinal chemistry 43 (4), 683-693, 2008 | 18 | 2008 |
1, 3, 4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity … H Käsnänen, A Minkkilä, S Taupila, JZ Patel, T Parkkari, ... European Journal of Pharmaceutical Sciences 49 (3), 423-433, 2013 | 17 | 2013 |
Docking-based 3D-QSAR studies for 1, 3, 4-oxadiazol-2-one derivatives as FAAH inhibitors A Zięba, T Laitinen, JZ Patel, A Poso, AA Kaczor International journal of molecular sciences 22 (11), 6108, 2021 | 15 | 2021 |
Chloroquine fumardiamides as novel quorum sensing inhibitors M Beus, K Savijoki, JZ Patel, J Yli-Kauhaluoma, A Fallarero, B Zorc Bioorganic & medicinal chemistry letters 30 (16), 127336, 2020 | 15 | 2020 |
Bioisosteric replacement of dihydropyrazole of 4S-(−)-3-(4-chlorophenyl)-N-methyl-N′-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4, 5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a … BK Srivastava, R Soni, A Joharapurkar, KVVM Sairam, JZ Patel, ... Bioorganic & medicinal chemistry letters 18 (3), 963-968, 2008 | 15 | 2008 |
Strategies to prevent biofilm infections on biomaterials: Effect of novel naturally-derived biofilm inhibitors on a competitive colonization model of titanium by Staphylococcus … I Reigada, R Pérez-Tanoira, JZ Patel, K Savijoki, J Yli-Kauhaluoma, ... Microorganisms 8 (3), 345, 2020 | 14 | 2020 |
Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11) D Navia-Paldanius, JZ Patel, ML Navarro, H Jakupović, S Goffart, ... European Journal of Pharmaceutical Sciences 93, 253-263, 2016 | 14 | 2016 |
Revisiting 1, 3, 4-oxadiazol-2-ones: utilization in the development of ABHD6 inhibitors JZ Patel, J van Bruchem, T Laitinen, AA Kaczor, D Navia-Paldanius, ... Bioorganic & Medicinal Chemistry 23 (19), 6335-6345, 2015 | 14 | 2015 |
Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxy lic acid piperidin-1 … B Kumar Srivastava, R Soni, JZ Patel, S Jha, S Shedage, N Gandhi, ... | 14* | 2008 |
Synthesis and in vitro antibacterial activity of novel methylamino piperidinyl oxazolidinones BK Srivastava, R Soni, JZ Patel, M Solanki, D Valani, S Gupta, B Mishra, ... Bioorganic & medicinal chemistry letters 17 (18), 5227-5232, 2007 | 13 | 2007 |