Прати
David Ochoa
David Ochoa
Platform Coordinator in OpenTargets (EMBL-EBI)
Верификована је имејл адреса на ebi.ac.uk - Почетна страница
Наслов
Навело
Навело
Година
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
M Ghoussaini, E Mountjoy, M Carmona, G Peat, EM Schmidt, A Hercules, ...
Nucleic acids research 49 (D1), D1311-D1320, 2021
4852021
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci
E Mountjoy, EM Schmidt, M Carmona, J Schwartzentruber, G Peat, ...
Nature genetics 53 (11), 1527-1533, 2021
4242021
The functional landscape of the human phosphoproteome
D Ochoa, AF Jarnuczak, C Viéitez, M Gehre, M Soucheray, A Mateus, ...
Nature biotechnology 38 (3), 365-373, 2020
4032020
Open Targets Platform: supporting systematic drug–target identification and prioritisation
D Ochoa, A Hercules, M Carmona, D Suveges, A Gonzalez-Uriarte, ...
Nucleic acids research 49 (D1), D1302-D1310, 2021
3722021
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
D Ochoa, A Hercules, M Carmona, D Suveges, J Baker, C Malangone, ...
Nucleic acids research 51 (D1), D1353-D1359, 2023
2522023
The protactable genome
M Schneider, CJ Radoux, A Hercules, D Ochoa, I Dunham, LP Zalmas, ...
Nature reviews Drug discovery 20 (10), 789-797, 2021
1822021
Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs
D Ochoa, M Karim, M Ghoussaini, DG Hulcoop, EM McDonagh, I Dunham
Nat Rev Drug Discov 21 (8), 551, 2022
1522022
An atlas of human kinase regulation
D Ochoa, M Jonikas, RT Lawrence, B El Debs, J Selkrig, A Typas, J Villén, ...
Molecular systems biology 12 (12), 888, 2016
1212016
Studying the co-evolution of protein families with the Mirrortree web server
D Ochoa, F Pazos
Bioinformatics 26 (10), 1370-1371, 2010
872010
Benchmarking substrate-based kinase activity inference using phosphoproteomic data
C Hernandez-Armenta, D Ochoa, E Gonçalves, J Saez-Rodriguez, ...
Bioinformatics 33 (12), 1845-1851, 2017
862017
Mondo: unifying diseases for the world, by the world
NA Vasilevsky, NA Matentzoglu, S Toro, JE Flack IV, H Hegde, DR Unni, ...
MedRxiv, 2022.04. 13.22273750, 2022
842022
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
N Del-Toro, M Duesbury, M Koch, L Perfetto, A Shrivastava, D Ochoa, ...
Nature communications 10 (1), 10, 2019
652019
Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs
D Juan, J Perner, EC de Santa Pau, S Marsili, D Ochoa, HR Chung, ...
Cell reports 14 (5), 1246-1257, 2016
612016
Network expansion of genetic associations defines a pleiotropy map of human cell biology
I Barrio-Hernandez, J Schwartzentruber, A Shrivastava, N Del-Toro, ...
Nature genetics 55 (3), 389-398, 2023
592023
Conserved phosphorylation hotspots in eukaryotic protein domain families
MJ Strumillo, M Oplová, C Viéitez, D Ochoa, M Shahraz, BP Busby, ...
Nature communications 10 (1), 1977, 2019
542019
High-throughput functional characterization of protein phosphorylation sites in yeast
C Viéitez, BP Busby, D Ochoa, A Mateus, D Memon, M Galardini, U Yildiz, ...
Nature Biotechnology 40 (3), 382-390, 2022
48*2022
Democratizing knowledge representation with BioCypher
S Lobentanzer, P Aloy, J Baumbach, B Bohar, VJ Carey, P Charoentong, ...
Nature Biotechnology 41 (8), 1056-1059, 2023
472023
Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast
E Gonçalves, Z Raguz Nakic, M Zampieri, O Wagih, D Ochoa, U Sauer, ...
PLoS computational biology 13 (1), e1005297, 2017
462017
Practical aspects of protein co-evolution
D Ochoa, F Pazos
Frontiers in cell and developmental biology 2, 14, 2014
402014
Detection of significant protein coevolution
D Ochoa, D Juan, A Valencia, F Pazos
Bioinformatics 31 (13), 2166-2173, 2015
342015
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Чланци 1–20