IL-1β drives inflammatory responses to propionibacterium acnes in vitro and in vivo M Kistowska, S Gehrke, D Jankovic, K Kerl, A Fettelschoss, L Feldmeyer, ... Journal of Investigative Dermatology 134 (3), 677-685, 2014 | 277 | 2014 |
Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages R Huber, B Meier, A Otsuka, G Fenini, T Satoh, S Gehrke, D Widmer, ... Scientific reports 6 (1), 29914, 2016 | 153 | 2016 |
Potential of IL-1, IL-18 and inflammasome inhibition for the treatment of inflammatory skin diseases G Fenini, E Contassot, LE French Frontiers in pharmacology 8, 278, 2017 | 151 | 2017 |
Genome editing of human primary keratinocytes by CRISPR/Cas9 reveals an essential role of the NLRP1 inflammasome in UVB sensing G Fenini, S Grossi, E Contassot, T Biedermann, E Reichmann, LE French, ... Journal of Investigative Dermatology 138 (12), 2644-2652, 2018 | 123 | 2018 |
Malassezia yeasts activate the NLRP3 inflammasome in antigen‐presenting cells via Syk‐kinase signalling M Kistowska, G Fenini, D Jankovic, L Feldmeyer, K Kerl, P Bosshard, ... Experimental dermatology 23 (12), 884-889, 2014 | 97 | 2014 |
The NLRP1 inflammasome in human skin and beyond G Fenini, T Karakaya, P Hennig, M Di Filippo, HD Beer International journal of molecular sciences 21 (13), 4788, 2020 | 93 | 2020 |
The pathways underlying the multiple roles of p62 in inflammation and cancer P Hennig, G Fenini, M Di Filippo, T Karakaya, HD Beer Biomedicines 9 (7), 707, 2021 | 71 | 2021 |
Opposing effects of Nrf2 and Nrf2‐activating compounds on the NLRP3 inflammasome independent of Nrf2‐mediated gene expression M Garstkiewicz, GE Strittmatter, S Grossi, J Sand, G Fenini, S Werner, ... European journal of immunology 47 (5), 806-817, 2017 | 60 | 2017 |
IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes TK Satoh, M Mellett, B Meier-Schiesser, G Fenini, A Otsuka, HD Beer, ... The Journal of clinical investigation 130 (3), 1417-1430, 2020 | 54 | 2020 |
Microcrystalline tyrosine and aluminum as adjuvants in allergen-specific immunotherapy protect from IgE-mediated reactivity in mouse models and act independently of … DS Leuthard, A Duda, SN Freiberger, S Weiss, I Dommann, G Fenini, ... The Journal of Immunology 200 (9), 3151-3159, 2018 | 50 | 2018 |
The p38 mitogen-activated protein kinase critically regulates human keratinocyte inflammasome activation G Fenini, S Grossi, S Gehrke, HD Beer, TK Satoh, E Contassot, LE French Journal of Investigative Dermatology 138 (6), 1380-1390, 2018 | 36 | 2018 |
Electrophiles against (skin) diseases: more than Nrf2 P Hennig, G Fenini, M Di Filippo, HD Beer Biomolecules 10 (2), 271, 2020 | 29 | 2020 |
The NLRP1 inflammasome pathway is silenced in cutaneous squamous cell carcinoma J Sand, G Fenini, S Grossi, P Hennig, M Di Filippo, M Levesque, S Werner, ... Journal of Investigative Dermatology 139 (8), 1788-1797. e6, 2019 | 28 | 2019 |
Inactivation of the cytoprotective major vault protein by caspase-1 and-9 in epithelial cells during apoptosis S Grossi, G Fenini, T Kockmann, P Hennig, M Di Filippo, HD Beer Journal of Investigative Dermatology 140 (7), 1335-1345. e10, 2020 | 25 | 2020 |
Metastatic melanoma cell lines do not secrete IL-1β but promote IL-1β production from macrophages S Gehrke, A Otsuka, R Huber, B Meier, M Kistowska, G Fenini, P Cheng, ... Journal of dermatological science 74 (2), 167-169, 2014 | 19 | 2014 |
NLRP1 inflammasome activation in keratinocytes: increasing evidence of important roles in inflammatory skin diseases and immunity G Fenini, T Karakaya, P Hennig, M Di Filippo, M Slaufova, HD Beer Journal of Investigative Dermatology 142 (9), 2313-2322, 2022 | 18 | 2022 |
Generation of knockout human primary keratinocytes by CRISPR/Cas9 S Grossi, G Fenini, P Hennig, M Di Filippo, HD Beer Epidermal Cells: Methods and Protocols, 125-145, 2020 | 9 | 2020 |
Phosphodiesterase-4 inhibition reduces cutaneous inflammation and IL-1β expression in a psoriasiform mouse model but does not inhibit inflammasome activation B Meier-Schiesser, M Mellett, MK Ramirez-Fort, JT Maul, A Klug, ... International Journal of Molecular Sciences 22 (23), 12878, 2021 | 5 | 2021 |
Efficient Generation of CRISPR/Cas9-Mediated Knockout Human Primary Keratinocytes by Electroporation T Karakaya, M Slaufova, M Di Filippo, P Hennig, G Fenini, T Kündig, ... Skin Stem Cells: Methods and Protocols, 73-86, 2024 | | 2024 |
Check for updates HPK by Electroporation, T Karakaya, M Slaufova, M Di Filippo, P Hennig, ... Skin Stem Cells: Methods and Protocols 2849, 73-86, 2024 | | 2024 |