| HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, JM Asara, ... Science 292 (5516), 464-468, 2001 | 6001 | 2001 |
| Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein M Ohh, CW Park, M Ivan, MA Hoffman, TY Kim, LE Huang, N Pavletich, ... Nature cell biology 2 (7), 423-427, 2000 | 2006 | 2000 |
| The updated biology of hypoxia‐inducible factor SN Greer, JL Metcalf, Y Wang, M Ohh The EMBO journal 31 (11), 2448-2460, 2012 | 694 | 2012 |
| The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix M Ohh, RL Yauch, KM Lonergan, JM Whaley, AO Stemmer-Rachamimov, ... Molecular cell 1 (7), 959-968, 1998 | 613 | 1998 |
| Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2 KM Lonergan, O Iliopoulos, M Ohh, T Kamura, RC Conaway, ... Molecular and cellular biology 18 (2), 732-741, 1998 | 528 | 1998 |
| von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF MA Hoffman, M Ohh, H Yang, JM Klco, M Ivan, WG Kaelin Jr Human molecular genetics 10 (10), 1019-1027, 2001 | 469 | 2001 |
| Multiple splice variants of the human HIF-3α locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex MA Maynard, H Qi, J Chung, EHL Lee, Y Kondo, S Hara, RC Conaway, ... Journal of Biological Chemistry 278 (13), 11032-11040, 2003 | 436 | 2003 |
| Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia CM Niemeyer, MW Kang, DH Shin, I Furlan, M Erlacher, NJ Bunin, ... Nature genetics 42 (9), 794-800, 2010 | 423 | 2010 |
| Differential dependence of hypoxia-inducible factors 1α and 2α on mTORC1 and mTORC2 A Toschi, E Lee, N Gadir, M Ohh, DA Foster Journal of Biological Chemistry 283 (50), 34495-34499, 2008 | 373 | 2008 |
| pVHL19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation O Iliopoulos, M Ohh, WG Kaelin Jr Proceedings of the National Academy of Sciences 95 (20), 11661-11666, 1998 | 347 | 1998 |
| VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail AJ Evans, RC Russell, O Roche, TN Burry, JE Fish, VWK Chow, WY Kim, ... Molecular and cellular biology 27 (1), 157-169, 2007 | 339 | 2007 |
| Human HIF‐3α4 is a dominant‐negative regulator of HIF‐1 and is down‐regulated in renal cell carcinoma MA Maynard, AJ Evans, T Hosomi, S Hara, MAS Jewett, M Ohh The FASEB journal 19 (11), 1396-1406, 2005 | 286 | 2005 |
| Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression RC O'Hagan, M Ohh, G David, IM De Alboran, FW Alt, WG Kaelin, ... Genes & development 14 (17), 2185-2191, 2000 | 270 | 2000 |
| Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis S Bunda, K Burrell, P Heir, L Zeng, A Alamsahebpour, Y Kano, B Raught, ... Nature communications 6 (1), 8859, 2015 | 264 | 2015 |
| pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development NH Stickle, J Chung, JM Klco, RP Hill, WG Kaelin Jr, M Ohh Molecular and cellular biology 24 (8), 3251-3261, 2004 | 242 | 2004 |
| Regulation of endocytosis via the oxygen-sensing pathway Y Wang, O Roche, MS Yan, G Finak, AJ Evans, JL Metcalf, BE Hast, ... Nature medicine 15 (3), 319-324, 2009 | 231 | 2009 |
| An intact NEDD8 pathway is required for Cullin‐dependent ubiquitylation in mammalian cells M Ohh, WY Kim, JJ Moslehi, Y Chen, V Chau, MA Read, WG KaelinJr EMBO reports, 2002 | 224 | 2002 |
| NEDD8 pathways in cancer, Sine Quibus Non IR Watson, MS Irwin, M Ohh Cancer cell 19 (2), 168-176, 2011 | 209 | 2011 |
| The role of hypoxia-inducible factors in cancer MA Maynard, M Ohh Cellular and molecular life sciences 64, 2170-2180, 2007 | 204 | 2007 |
| Nucleolar RNA polymerase II drives ribosome biogenesis KJ Abraham, N Khosraviani, JNY Chan, A Gorthi, A Samman, DY Zhao, ... Nature 585 (7824), 298-302, 2020 | 195 | 2020 |