| Coumaric acid derivatives as tyrosinase inhibitors: Efficacy studies through in silico, in vitro and ex vivo approaches MT Varela, M Ferrarini, VG Mercaldi, B da Silva Sufi, G Padovani, ... Bioorganic Chemistry 103, 104108, 2020 | 47 | 2020 |
| Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified … TR Morais, GAA Conserva, MT Varela, TA Costa-Silva, F Thevenard, ... Scientific Reports 10 (1), 5467, 2020 | 31 | 2020 |
| Gibbilimbol analogues as antiparasitic agents—Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum MT Varela, RZ Dias, LF Martins, DD Ferreira, AG Tempone, AK Ueno, ... Bioorganic & medicinal chemistry letters 26 (4), 1180-1183, 2016 | 29 | 2016 |
| New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum MT Varela, ML Lima, MK Galuppo, AG Tempone, A de Oliveira, JHG Lago, ... Chemical Biology & Drug Design 90 (5), 1007-1011, 2017 | 22 | 2017 |
| Natural products: Key prototypes to drug discovery against neglected diseases caused by trypanosomatids MT Varela, JPS Fernandes Current medicinal chemistry 27 (13), 2133-2146, 2020 | 18 | 2020 |
| Coumaric acid analogues inhibit growth and melanin biosynthesis in Cryptococcus neoformans and potentialize amphotericin B antifungal activity L Oliveira, M Ferrarini, AP Dos Santos, MT Varela, ITS Corrêa, ... European Journal of Pharmaceutical Sciences 153, 105473, 2020 | 16 | 2020 |
| Antiparasitic activity of new gibbilimbol analogues and SAR analysis through efficiency and statistical methods MT Varela, MM Romaneli, ML Lima, SET Borborema, AG Tempone, ... European Journal of Pharmaceutical Sciences 122, 31-41, 2018 | 15 | 2018 |
| 1‐[(2,3‐Dihydro‐1‐benzofuran‐2‐yl) methyl]piperazines as novel anti‐inflammatory compounds: Synthesis and evaluation on H3R/H4R MF Corrêa, MT Varela, AM Balbino, AC Torrecilhas, RG Landgraf, ... Chemical Biology & Drug Design 90 (2), 317-322, 2017 | 14 | 2017 |
| Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives MT Varela, TA Costa-Silva, JHG Lago, AG Tempone, JPS Fernandes Bioorganic Chemistry 89, 102996, 2019 | 13 | 2019 |
| Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi MT Varela, M Amaral, MM Romanelli, EV de Castro Levatti, AG Tempone, ... European Journal of Pharmaceutical Sciences 171, 106114, 2022 | 7 | 2022 |
| Novel potent (dihydro) benzofuranyl piperazines as human histamine receptor ligands–Functional characterization and modeling studies on H3 and H4 receptors MF Corrêa, AL Balico-Silva, DJ Kiss, GAB Fernandes, JC Maraschin, ... Bioorganic & Medicinal Chemistry 30, 115924, 2021 | 6 | 2021 |
| Profiling of LINS01 compounds at human dopamine D2 and D3 receptors MF Corrêa, D Reiner, GAB Fernandes, MT Varela, CMSQ Aranha, H Stark, ... Journal of Chemical Sciences 132, 1-6, 2020 | 6 | 2020 |
| Investigation of Structure–Activity Relationships for Benzoyl and Cinnamoyl Piperazine/Piperidine Amides as Tyrosinase Inhibitors MT Varela, EV de Castro Levatti, AG Tempone, JPS Fernandes ACS omega 8 (46), 44265-44275, 2023 | 5 | 2023 |
| Piperazine amides with desirable solubility, physicochemical and drug-like properties: Synthesis and evaluation of the anti-Trypanosoma cruzi activity MT Varela, M Romanelli, M Amaral, AG Tempone, JPS Fernandes Saudi Pharmaceutical Journal 31 (7), 1265-1273, 2023 | 5 | 2023 |
| Bioisosteric modification on benzylidene‐carbonyl compounds improved the drug‐likeness and maintained the antifungal activity against Sporothrix brasiliensis SB Waller, MB Cleff, MK Ripoll, MCA Meireles, M Ferrarini, MT Varela, ... Chemical Biology & Drug Design 99 (3), 391-397, 2022 | 4 | 2022 |
| Esterification of p-Coumaric Acid Improves the Control over Melanoma Cell Growth JI Carmo-Martins, MB Gonzatti, MT Varela, MEP Sousa, LVS Costa, ... Biomedicines 11 (1), 196, 2023 | 2 | 2023 |
| Benzylidene-carbonyl compounds are active against itraconazole-susceptible and itraconazole-resistant Sporothrix brasiliensis SB Waller, MB Cleff, MK Ripoll, MCA Meireles, MT Varela, JPS Fernandes Folia Microbiologica 65, 1033-1038, 2020 | 2 | 2020 |
| Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi M Amaral, MT Varela, R Kant, M Christodoulides, JPS Fernandes, ... Life 13 (3), 663, 2023 | 1 | 2023 |
| Pyrazinoates as antiparasitic agents against Trypanosoma cruzi CI Vasconcelos, MT Varela, AC Torrecilhas, JPS Fernandes Archiv der Pharmazie 351 (11), 1800190, 2018 | 1 | 2018 |
| Spirocyclic compounds as innovative tools in drug discovery for medicinal chemists MT Varela, GG Dias, LFN de Oliveira, RG de Oliveira, FD Aguiar, ... European Journal of Medicinal Chemistry, 117368, 2025 | | 2025 |
João Paulo dos Santos FernandesUniversidade Federal de São PauloVerifierad e-postadress på unifesp.br