| The interplay between cell signalling and the mevalonate pathway in cancer PJ Mullen, R Yu, J Longo, MC Archer, LZ Penn Nature Reviews Cancer 16 (11), 718-731, 2016 | 640 | 2016 |
| Antagonistic regulation of motility and transcriptome expression by RpoN and RpoS in Escherichia coli T Dong, R Yu, H Schellhorn Molecular microbiology 79 (2), 375-386, 2011 | 121 | 2011 |
| Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop A Pandyra, PJ Mullen, M Kalkat, R Yu, JT Pong, Z Li, S Trudel, KS Lang, ... Cancer research 74 (17), 4772-4782, 2014 | 86 | 2014 |
| An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer J Longo, PJ Mullen, R Yu, JE van Leeuwen, M Masoomian, DTS Woon, ... Molecular metabolism 25, 119-130, 2019 | 74 | 2019 |
| Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast R Yu, K Campbell, R Pereira, J Björkeroth, Q Qi, E Vorontsov, C Sihlbom, ... Nature communications 11 (1), 1881, 2020 | 73 | 2020 |
| Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death AA Pandyra, PJ Mullen, CA Goard, E Ericson, P Sharma, M Kalkat, R Yu, ... Oncotarget 6 (29), 26909, 2015 | 73 | 2015 |
| Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast C Malina, R Yu, J Björkeroth, EJ Kerkhoven, J Nielsen Proceedings of the National Academy of Sciences 118 (51), e2112836118, 2021 | 71 | 2021 |
| Statin-induced cancer cell death can be mechanistically uncoupled from prenylation of RAS family proteins R Yu, J Longo, JE van Leeuwen, PJ Mullen, W Ba-Alawi, B Haibe-Kains, ... Cancer research 78 (5), 1347-1357, 2018 | 70 | 2018 |
| Polymorphism and selection of rpoS in pathogenic Escherichia coli T Dong, SM Chiang, C Joyce, R Yu, HE Schellhorn BMC microbiology 9, 1-13, 2009 | 60 | 2009 |
| Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media J Björkeroth, K Campbell, C Malina, R Yu, F Di Bartolomeo, J Nielsen Proceedings of the National Academy of Sciences 117 (35), 21804-21812, 2020 | 57 | 2020 |
| Recent applications of engineered animal antioxidant deficiency models in human nutrition and chronic disease R Yu, HE Schellhorn The Journal of nutrition 143 (1), 1-11, 2013 | 37 | 2013 |
| Mevalonate Pathway Inhibition Slows Breast Cancer Metastasis via Reduced N-glycosylation Abundance and Branching R Yu, J Longo, JE van Leeuwen, C Zhang, E Branchard, M Elbaz, ... Cancer research 81 (10), 2625-2635, 2021 | 33 | 2021 |
| Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection H Lu, F Li, L Yuan, I Domenzain, R Yu, H Wang, G Li, Y Chen, B Ji, ... Molecular Systems Biology 17 (10), e10427, 2021 | 29 | 2021 |
| Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast R Yu, E Vorontsov, C Sihlbom, J Nielsen Elife 10, e65722, 2021 | 27 | 2021 |
| Big data in yeast systems biology R Yu, J Nielsen FEMS yeast research 19 (7), foz070, 2019 | 24 | 2019 |
| Different routes of protein folding contribute to improved protein production in Saccharomyces cerevisiae Q Qi, F Li, R Yu, MKM Engqvist, V Siewers, J Fuchs, J Nielsen Mbio 11 (6), 10.1128/mbio. 02743-20, 2020 | 22 | 2020 |
| Benchmarking accuracy and precision of intensity‐based absolute quantification of protein abundances in Saccharomyces cerevisiae BJ Sánchez, PJ Lahtvee, K Campbell, S Kasvandik, R Yu, I Domenzain, ... Proteomics 21 (6), 2000093, 2021 | 20 | 2021 |
| Yeast systems biology in understanding principles of physiology underlying complex human diseases R Yu, J Nielsen Current opinion in biotechnology 63, 63-69, 2020 | 11 | 2020 |
| A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance TW Doughty, R Yu, LFI Chao, Z Qin, V Siewers, J Nielsen BMC genomics 22, 1-12, 2021 | 4 | 2021 |
| Non-random organization of flux control mechanisms in yeast central metabolic pathways R Yu, E Vorontsov, C Sihlbom, J Nielsen bioRxiv, 2021.12. 15.472747, 2021 | 1 | 2021 |