| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13714* | 2021 |
| A guide to immunometabolism for immunologists LAJ O'Neill, RJ Kishton, J Rathmell Nature reviews immunology 16 (9), 553-565, 2016 | 2850 | 2016 |
| Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets RD Michalek, VA Gerriets, SR Jacobs, AN Macintyre, NJ MacIver, ... The Journal of immunology 186 (6), 3299-3303, 2011 | 2237 | 2011 |
| The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues T Lindsten, AJ Ross, A King, WX Zong, JC Rathmell, HA Shiels, E Ulrich, ... Molecular cell 6 (6), 1389-1399, 2000 | 1872 | 2000 |
| The CD28 signaling pathway regulates glucose metabolism KA Frauwirth, JL Riley, MH Harris, RV Parry, JC Rathmell, DR Plas, ... Immunity 16 (6), 769-777, 2002 | 1727 | 2002 |
| Metabolic regulation of T lymphocytes NJ MacIver, RD Michalek, JC Rathmell Annual review of immunology 31 (1), 259-283, 2013 | 1376 | 2013 |
| Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1371 | 2015 |
| The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function AN Macintyre, VA Gerriets, AG Nichols, RD Michalek, MC Rudolph, ... Cell metabolism 20 (1), 61-72, 2014 | 1178 | 2014 |
| Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways SR Jacobs, CE Herman, NJ MacIver, JA Wofford, HL Wieman, ... The Journal of Immunology 180 (7), 4476-4486, 2008 | 964 | 2008 |
| Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype AJ Freemerman, AR Johnson, GN Sacks, JJ Milner, EL Kirk, MA Troester, ... Journal of Biological Chemistry 289 (11), 7884-7896, 2014 | 962 | 2014 |
| Cell-programmed nutrient partitioning in the tumour microenvironment BI Reinfeld, MZ Madden, MM Wolf, A Chytil, JE Bader, AR Patterson, ... Nature 593 (7858), 282-288, 2021 | 772 | 2021 |
| Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 728 | 2015 |
| Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking HL Wieman, JA Wofford, JC Rathmell Molecular biology of the cell 18 (4), 1437-1446, 2007 | 720 | 2007 |
| Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival JC Rathmell, CJ Fox, DR Plas, PS Hammerman, RM Cinalli, ... Molecular and cellular biology, 2003 | 718 | 2003 |
| Targeting metabolism to improve the tumor microenvironment for cancer immunotherapy JE Bader, K Voss, JC Rathmell Molecular cell 78 (6), 1019-1033, 2020 | 711 | 2020 |
| Amino acids rather than glucose account for the majority of cell mass in proliferating mammalian cells AM Hosios, VC Hecht, LV Danai, MO Johnson, JC Rathmell, ... Developmental cell 36 (5), 540-549, 2016 | 683 | 2016 |
| Pathways of apoptosis in lymphocyte development, homeostasis, and disease JC Rathmell, CB Thompson Cell 109 (2), S97-S107, 2002 | 682 | 2002 |
| Growth factors can influence cell growth and survival through effects on glucose metabolism MG Vander Heiden, DR Plas, JC Rathmell, CJ Fox, MH Harris, ... Molecular and cellular biology 21 (17), 5899-5912, 2001 | 679 | 2001 |
| Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ... Cell 175 (7), 1780-1795. e19, 2018 | 608 | 2018 |
| Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival NJ MacIver, SR Jacobs, HL Wieman, JA Wofford, JL Coloff, JC Rathmell Journal of Leucocyte Biology 84 (4), 949-957, 2008 | 605 | 2008 |
