A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans DK Bricker, EB Taylor, JC Schell, T Orsak, A Boutron, YC Chen, JE Cox, ... Science 337 (6090), 96-100, 2012 | 965 | 2012 |
Procedures for behavioral experiments in head-fixed mice ZV Guo, SA Hires, N Li, DH O'Connor, T Komiyama, E Ophir, D Huber, ... PloS one 9 (2), e88678, 2014 | 482 | 2014 |
Methods for studying metabolism in Drosophila JM Tennessen, WE Barry, J Cox, CS Thummel Methods 68 (1), 105-115, 2014 | 446 | 2014 |
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis B Chaurasia, TS Tippetts, R Mayoral Monibas, J Liu, Y Li, L Wang, ... Science 365 (6451), 386-392, 2019 | 417 | 2019 |
Gut microbes of mammalian herbivores facilitate intake of plant toxins KD Kohl, RB Weiss, J Cox, C Dale, M Denise Dearing Ecology letters 17 (10), 1238-1246, 2014 | 341 | 2014 |
T cell–mediated regulation of the microbiota protects against obesity C Petersen, R Bell, KA Klag, SH Lee, R Soto, A Ghazaryan, K Buhrke, ... Science 365 (6451), eaat9351, 2019 | 337 | 2019 |
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains PS Shen, J Park, Y Qin, X Li, K Parsawar, MH Larson, J Cox, Y Cheng, ... Science 347 (6217), 75-78, 2015 | 315 | 2015 |
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism JC Schell, DR Wisidagama, C Bensard, H Zhao, P Wei, J Tanner, A Flores, ... Nature cell biology 19 (9), 1027-1036, 2017 | 300 | 2017 |
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis B Coste, G Houge, MF Murray, N Stitziel, M Bandell, MA Giovanni, ... Proceedings of the National Academy of Sciences 110 (12), 4667-4672, 2013 | 252 | 2013 |
Global analysis of plasma lipids identifies liver-derived acylcarnitines as a fuel source for brown fat thermogenesis J Simcox, G Geoghegan, JA Maschek, CL Bensard, M Pasquali, R Miao, ... Cell metabolism 26 (3), 509-522. e6, 2017 | 246 | 2017 |
Energetic trade-offs and hypometabolic states promote disease tolerance K Ganeshan, J Nikkanen, K Man, YA Leong, Y Sogawa, JA Maschek, ... Cell 177 (2), 399-413. e12, 2019 | 245 | 2019 |
Hepatic mitochondrial pyruvate carrier 1 is required for efficient regulation of gluconeogenesis and whole-body glucose homeostasis LR Gray, MR Sultana, AJ Rauckhorst, L Oonthonpan, SC Tompkins, ... Cell metabolism 22 (4), 669-681, 2015 | 234 | 2015 |
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice TR Chiaro, R Soto, W Zac Stephens, JL Kubinak, C Petersen, L Gogokhia, ... Science translational medicine 9 (380), eaaf9044, 2017 | 224 | 2017 |
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure AA Cluntun, R Badolia, S Lettlova, KM Parnell, TS Shankar, NA Diakos, ... Cell metabolism 33 (3), 629-648. e10, 2021 | 216 | 2021 |
Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease AM Poss, JA Maschek, JE Cox, BJ Hauner, PN Hopkins, SC Hunt, ... The Journal of clinical investigation 130 (3), 1363-1376, 2020 | 202 | 2020 |
Metabolic response to iron deficiency in Saccharomyces cerevisiae M Shakoury-Elizeh, O Protchenko, A Berger, J Cox, K Gable, TM Dunn, ... Journal of Biological Chemistry 285 (19), 14823-14833, 2010 | 202 | 2010 |
Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis MS Donia, WF Fricke, F Partensky, J Cox, SI Elshahawi, JR White, ... Proceedings of the National Academy of Sciences 108 (51), E1423-E1432, 2011 | 184 | 2011 |
Zebrafish screen identifies novel compound with selective toxicity against leukemia S Ridges, WL Heaton, D Joshi, H Choi, A Eiring, L Batchelor, P Choudhry, ... Blood, The Journal of the American Society of Hematology 119 (24), 5621-5631, 2012 | 171 | 2012 |
Iron chaperone poly rC binding protein 1 protects mouse liver from lipid peroxidation and steatosis O Protchenko, E Baratz, S Jadhav, F Li, M Shakoury‐Elizeh, O Gavrilova, ... Hepatology 73 (3), 1176-1193, 2021 | 148* | 2021 |
Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis JM Tennessen, NM Bertagnolli, J Evans, MH Sieber, J Cox, CS Thummel G3: Genes, Genomes, Genetics 4 (5), 839-850, 2014 | 148 | 2014 |