Structure of the Nav1. 4-β1 complex from electric eel Z Yan, Q Zhou, L Wang, J Wu, Y Zhao, G Huang, W Peng, H Shen, J Lei, ... Cell 170 (3), 470-482. e11, 2017 | 357 | 2017 |
Structure of a yeast activated spliceosome at 3.5 Å resolution C Yan, R Wan, R Bai, G Huang, Y Shi Science 353 (6302), 904-911, 2016 | 288 | 2016 |
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA X Pan, Z Li, X Huang, G Huang, S Gao, H Shen, L Liu, J Lei, N Yan Science 363 (6433), 1309-1313, 2019 | 241 | 2019 |
Molecular basis for ligand modulation of a mammalian voltage-gated Ca2+ channel Y Zhao, G Huang, J Wu, Q Wu, S Gao, Z Yan, J Lei, N Yan Cell 177 (6), 1495-1506. e12, 2019 | 233 | 2019 |
Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution R Wan, C Yan, R Bai, G Huang, Y Shi Science 353 (6302), 895-904, 2016 | 209 | 2016 |
Cryo-EM structures of apo and antagonist-bound human Cav3. 1 Y Zhao, G Huang, Q Wu, K Wu, R Li, J Lei, X Pan, N Yan Nature 576 (7787), 492-497, 2019 | 168 | 2019 |
Structure of a yeast step II catalytically activated spliceosome C Yan, R Wan, R Bai, G Huang, Y Shi Science 355 (6321), 149-155, 2017 | 160 | 2017 |
Modulation of cardiac ryanodine receptor 2 by calmodulin D Gong, X Chi, J Wei, G Zhou, G Huang, L Zhang, R Wang, J Lei, ... Nature 572 (7769), 347-351, 2019 | 154 | 2019 |
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin D Gong, X Chi, K Ren, G Huang, G Zhou, N Yan, J Lei, Q Zhou Nature communications 9 (1), 3623, 2018 | 98 | 2018 |
Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1.5 by the Antiarrhythmic Drug Quinidine** Z Li, X Jin, T Wu, G Huang, K Wu, J Lei, X Pan, N Yan Angewandte Chemie 133 (20), 11575-11581, 2021 | 95 | 2021 |
Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies X Pan, Z Li, X Jin, Y Zhao, G Huang, X Huang, Z Shen, Y Cao, M Dong, ... Proceedings of the National Academy of Sciences 118 (11), e2100066118, 2021 | 93 | 2021 |
Structural basis for high-voltage activation and subtype-specific inhibition of human Nav1.8 X Huang, X Jin, G Huang, J Huang, T Wu, Z Li, J Chen, F Kong, X Pan, ... Proceedings of the National Academy of Sciences 119 (30), e2208211119, 2022 | 77 | 2022 |
Cryo-EM structure of the human IgM B cell receptor Q Su, M Chen, Y Shi, X Zhang, G Huang, B Huang, D Liu, Z Liu, Y Shi Science 377 (6608), 875-880, 2022 | 70 | 2022 |
Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex Y Zhang, S Li, C Zeng, G Huang, X Zhu, Q Wang, K Wang, Q Zhou, C Yan, ... Cell research 30 (6), 532-540, 2020 | 69 | 2020 |
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex X Zhu, G Huang, C Zeng, X Zhan, K Liang, Q Xu, Y Zhao, P Wang, ... Science 376 (6598), eabl8280, 2022 | 68 | 2022 |
High-resolution structures of human Nav1. 7 reveal gating modulation through α-π helical transition of S6IV G Huang, D Liu, W Wang, Q Wu, J Chen, X Pan, H Shen, N Yan Cell Reports 39 (4), 2022 | 60 | 2022 |
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis G Huang, Y Zhang, X Zhu, C Zeng, Q Wang, Q Zhou, Q Tao, M Liu, J Lei, ... Cell research 30 (6), 520-531, 2020 | 60 | 2020 |
Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators X Chi, D Gong, K Ren, G Zhou, G Huang, J Lei, Q Zhou, N Yan Proceedings of the National Academy of Sciences 116 (51), 25575-25582, 2019 | 54 | 2019 |
Structural mapping of Nav1.7 antagonists Q Wu, J Huang, X Fan, K Wang, X Jin, G Huang, J Li, X Pan, N Yan Nature Communications 14 (1), 3224, 2023 | 43 | 2023 |
Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Nav1.7 G Huang, Q Wu, Z Li, X Jin, X Huang, T Wu, X Pan, N Yan Proceedings of the National Academy of Sciences 119 (33), e2209164119, 2022 | 42 | 2022 |