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Gaoxingyu Huang
Gaoxingyu Huang
Westlake University
Verifierad e-postadress på westlake.edu.cn
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Structure of the Nav1. 4-β1 complex from electric eel
Z Yan, Q Zhou, L Wang, J Wu, Y Zhao, G Huang, W Peng, H Shen, J Lei, ...
Cell 170 (3), 470-482. e11, 2017
3572017
Structure of a yeast activated spliceosome at 3.5 Å resolution
C Yan, R Wan, R Bai, G Huang, Y Shi
Science 353 (6302), 904-911, 2016
2882016
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA
X Pan, Z Li, X Huang, G Huang, S Gao, H Shen, L Liu, J Lei, N Yan
Science 363 (6433), 1309-1313, 2019
2412019
Molecular basis for ligand modulation of a mammalian voltage-gated Ca2+ channel
Y Zhao, G Huang, J Wu, Q Wu, S Gao, Z Yan, J Lei, N Yan
Cell 177 (6), 1495-1506. e12, 2019
2332019
Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution
R Wan, C Yan, R Bai, G Huang, Y Shi
Science 353 (6302), 895-904, 2016
2092016
Cryo-EM structures of apo and antagonist-bound human Cav3. 1
Y Zhao, G Huang, Q Wu, K Wu, R Li, J Lei, X Pan, N Yan
Nature 576 (7787), 492-497, 2019
1682019
Structure of a yeast step II catalytically activated spliceosome
C Yan, R Wan, R Bai, G Huang, Y Shi
Science 355 (6321), 149-155, 2017
1602017
Modulation of cardiac ryanodine receptor 2 by calmodulin
D Gong, X Chi, J Wei, G Zhou, G Huang, L Zhang, R Wang, J Lei, ...
Nature 572 (7769), 347-351, 2019
1542019
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin
D Gong, X Chi, K Ren, G Huang, G Zhou, N Yan, J Lei, Q Zhou
Nature communications 9 (1), 3623, 2018
982018
Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1.5 by the Antiarrhythmic Drug Quinidine**
Z Li, X Jin, T Wu, G Huang, K Wu, J Lei, X Pan, N Yan
Angewandte Chemie 133 (20), 11575-11581, 2021
952021
Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies
X Pan, Z Li, X Jin, Y Zhao, G Huang, X Huang, Z Shen, Y Cao, M Dong, ...
Proceedings of the National Academy of Sciences 118 (11), e2100066118, 2021
932021
Structural basis for high-voltage activation and subtype-specific inhibition of human Nav1.8
X Huang, X Jin, G Huang, J Huang, T Wu, Z Li, J Chen, F Kong, X Pan, ...
Proceedings of the National Academy of Sciences 119 (30), e2208211119, 2022
772022
Cryo-EM structure of the human IgM B cell receptor
Q Su, M Chen, Y Shi, X Zhang, G Huang, B Huang, D Liu, Z Liu, Y Shi
Science 377 (6608), 875-880, 2022
702022
Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex
Y Zhang, S Li, C Zeng, G Huang, X Zhu, Q Wang, K Wang, Q Zhou, C Yan, ...
Cell research 30 (6), 532-540, 2020
692020
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex
X Zhu, G Huang, C Zeng, X Zhan, K Liang, Q Xu, Y Zhao, P Wang, ...
Science 376 (6598), eabl8280, 2022
682022
High-resolution structures of human Nav1. 7 reveal gating modulation through α-π helical transition of S6IV
G Huang, D Liu, W Wang, Q Wu, J Chen, X Pan, H Shen, N Yan
Cell Reports 39 (4), 2022
602022
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis
G Huang, Y Zhang, X Zhu, C Zeng, Q Wang, Q Zhou, Q Tao, M Liu, J Lei, ...
Cell research 30 (6), 520-531, 2020
602020
Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators
X Chi, D Gong, K Ren, G Zhou, G Huang, J Lei, Q Zhou, N Yan
Proceedings of the National Academy of Sciences 116 (51), 25575-25582, 2019
542019
Structural mapping of Nav1.7 antagonists
Q Wu, J Huang, X Fan, K Wang, X Jin, G Huang, J Li, X Pan, N Yan
Nature Communications 14 (1), 3224, 2023
432023
Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Nav1.7
G Huang, Q Wu, Z Li, X Jin, X Huang, T Wu, X Pan, N Yan
Proceedings of the National Academy of Sciences 119 (33), e2209164119, 2022
422022
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Artiklar 1–20