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Michael Rosen
Michael Rosen
UT Southwestern Medical Center
Verifierad e-postadress på utsouthwestern.edu - Startsida
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Biomolecular condensates: organizers of cellular biochemistry
SF Banani, HO Lee, AA Hyman, MK Rosen
Nature reviews Molecular cell biology 18 (5), 285-298, 2017
50952017
Phase transitions in the assembly of multivalent signalling proteins
P Li, S Banjade, HC Cheng, S Kim, B Chen, L Guo, M Llaguno, ...
Nature 483 (7389), 336-340, 2012
24462012
Formation and maturation of phase-separated liquid droplets by RNA-binding proteins
Y Lin, DSW Protter, MK Rosen, R Parker
Molecular cell 60 (2), 208-219, 2015
16332015
Compositional control of phase-separated cellular bodies
SF Banani, AM Rice, WB Peeples, Y Lin, S Jain, R Parker, MK Rosen
Cell 166 (3), 651-663, 2016
12312016
Phase separation of signaling molecules promotes T cell receptor signal transduction
X Su, JA Ditlev, E Hui, W Xing, S Banjade, J Okrut, DS King, J Taunton, ...
Science 352 (6285), 595-599, 2016
11592016
Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein
AS Kim, LT Kakalis, N Abdul-Manan, GA Liu, MK Rosen
Nature 404 (6774), 151-158, 2000
9822000
Organization of chromatin by intrinsic and regulated phase separation
BA Gibson, LK Doolittle, MWG Schneider, LE Jensen, N Gamarra, ...
Cell 179 (2), 470-484. e21, 2019
9462019
Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein
CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ...
Molecular cell 63 (1), 72-85, 2016
7622016
A framework for understanding the functions of biomolecular condensates across scales
AS Lyon, WB Peeples, MK Rosen
Nature Reviews Molecular Cell Biology 22 (3), 215-235, 2021
6682021
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
TS Harmon, AS Holehouse, MK Rosen, RV Pappu
elife 6, e30294, 2017
6242017
Phase transitions of multivalent proteins can promote clustering of membrane receptors
S Banjade, MK Rosen
elife 3, e04123, 2014
5882014
Structure and control of the actin regulatory WAVE complex
Z Chen, D Borek, SB Padrick, TS Gomez, Z Metlagel, AM Ismail, ...
Nature 468 (7323), 533-538, 2010
5752010
Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia
K Devriendt, AS Kim, G Mathijs, SGM Frints, M Schwartz, JJ Van den Oord, ...
Nature genetics 27 (3), 313-317, 2001
5142001
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
T Otomo, DR Tomchick, C Otomo, SC Panchal, M Machius, MK Rosen
Nature 433 (7025), 488-494, 2005
4992005
Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
B Aghazadeh, WE Lowry, XY Huang, MK Rosen
Cell 102 (5), 625-633, 2000
4812000
Solution structure of the SH3 domain of Src and identification of its ligand-binding site
H Yu, MK Rosen, TB Shin, C Seidel-Dugan, JS Brugge, SL Schreiber
Science 258 (5088), 1665-1668, 1992
4481992
Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’protein
N Abdul-Manan, B Aghazadeh, GA Liu, A Majumdar, O Ouerfelli, ...
Nature 399 (6734), 379-383, 1999
4391999
Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
LB Case, X Zhang, JA Ditlev, MK Rosen
Science 363 (6431), 1093-1097, 2019
4232019
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin
SW Michnick, MK Rosen, TJ Wandless, M Karplus, SL Schreiber
Science 252 (5007), 836-839, 1991
3861991
Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
Y Lin, SL Currie, MK Rosen
Journal of Biological Chemistry 292 (46), 19110-19120, 2017
3812017
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Artiklar 1–20